Video_2_Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish.MP4 by Lise Heylen (11561266)

ARHGAP15 protects GC cells from oxidative stress-induced cell death. by Fei-fei Zhang (10167371)

ARHGAP15 promotes ECM-detached tumor cell survival and colony formation under oxidative stress. by Fei-fei Zhang (10167371)

p75^NTR small molecule ligands protect neurons from Aβ-induced death. by Tao Yang (184280)

“…<p>6–7 DIV hippocampal, cortical and septal neurons were exposed to: culture medium alone (CM); CM containing 10 µM Aβ(S), a control peptide containing Aβ(1-42) residues in a scrambled sequence; 10 µM Aβ alone or with NGF (100 ng/ml , ∼4 nM), LM11A-24, -31, or -36 (100 nM). …”

VER-155008 caused a significant reduction in viral transcripts in HEK-293T rKSHV.219 cells. by Belinda Baquero-Pérez (706834)

“…(C) At 4 h AcD treatment <i>SRAG</i> mRNA levels were reduced by 50% showing a relatively short stability. (D) <i>H2A</i>.…”

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition by Naping Hu (2614399)

“…The aim of this study was to investigate whether Hydroxysafflor yellow A (HSYA) can preserve renal function by inhibiting the progression of renal fibrosis and the potential mechanisms.…”

Supplementary Material for: Association between Hypouricemia and Reduced Kidney Function: A Cross-Sectional Population-Based Study in Japan by Wakasugi M. (4152238)

“…Hypouricemia was associated with reduced kidney function in men (odds ratio, 1.83; 95% confidence interval, 1.23-2.74), but not in women (0.61; 0.43-0.86), relative to the reference category (i.e., serum uric acid levels of 4.1-5.0 mg/dl) after adjusting for age, drinking, smoking, diabetes, hypertension, hypercholesterolemia, obesity, and history of renal failure. …”

Table_1_Evolving a New Efficient Mode of Fructose Utilization for Improved Bioproduction in Corynebacterium glutamicum.DOCX by Irene Krahn (10888566)

“…This is known to result in a significantly reduced oxidative pentose phosphate pathway (oxPPP) flux on fructose (∼10%) compared to glucose (∼60%). …”

Table_1_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.xlsx by Jun Tang (32983)

“…The family Rikenellaceae id.967 was associated with a reduced risk of both AS (OR = 0.66 (95% CI: 0.47–0.93); p = 1.81E−02) and psoriatic arthritis (OR = 0.70 (95% CI: 0.50–0.97); p = 3.00E−02). …”

Table_3_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.xlsx by Jun Tang (32983)

“…The family Rikenellaceae id.967 was associated with a reduced risk of both AS (OR = 0.66 (95% CI: 0.47–0.93); p = 1.81E−02) and psoriatic arthritis (OR = 0.70 (95% CI: 0.50–0.97); p = 3.00E−02). …”

Data_Sheet_1_Biocontrol Potential of a Novel Endophytic Bacterium From Mulberry (Morus) Tree.docx by Sen Xie (8349420)

“…Moreover, when applied to the generalist herbivore Spodoptera litura, ZJU1 was sufficient to reduce the pest survival rate below 50%. A previously undiscovered crystal toxin (Cry10Aa) could contribute to this insecticidal effect against notorious lepidopteran pests. …”

<i>Toxoplasma gondii</i> serine-protease inhibitor-1: A new adjuvant candidate for asthma therapy by Ariadna S. Soto (4538035)

“…This effect was accompanied by a lung resistance reduction of 26.3% and 50.3% respectively. …”

<i>fahd-1(tm5005) C</i>. <i>elegans</i> have a locomotion deficit. by Andrea Taferner (782532)

“…(B) 4-day old wild type and <i>fahd-1(tm5005)</i> worms were put in the center of an NGM plate seeded with <i>E</i>. <i>coli</i> OP50. The radial dispersal rate (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134161#sec002" target="_blank">Materials and Methods</a>) was determined for three different time points (30 sec, 1 min, 2 min). …”

Substrate-Dependent Inhibition of the Human Organic Cation Transporter OCT2: A Comparison of Metformin with Experimental Substrates by Kristina Hacker (773425)

“…<div><p>The importance of the organic cation transporter OCT2 in the renal excretion of cationic drugs raises the possibility of drug-drug interactions (DDIs) in which an inhibitor (perpetrator) drug decreases OCT2-dependent renal clearance of a victim (substrate) drug. …”

Table 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.xlsx by Yi Kang (387134)

“…</p>Result<p>MR analysis indicated that glucosamine was associated with increased cognitive performance (p = 8.46E-04), FIS (p = 7.50E-04), ALM (p = 6.45E-08), WBFM (p = 1.97E-03), usual walking pace (p = 2.55E-07), and moderate to vigorous physical activity levels (p = 3.29E-03), but associated with decreased FA risk (p = 3.77E-05) and DNA methylation GrimAge acceleration (p = 0.001). …”

Table_2_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.xlsx by Jun Tang (32983)

“…The family Rikenellaceae id.967 was associated with a reduced risk of both AS (OR = 0.66 (95% CI: 0.47–0.93); p = 1.81E−02) and psoriatic arthritis (OR = 0.70 (95% CI: 0.50–0.97); p = 3.00E−02). …”

Acute Febrile Illness and Influenza Disease Burden in a Rural Cohort Dedicated to Malaria in Senegal, 2012–2013 by Fatoumata Diene Sarr (2836526)

“…</p><p>Results</p><p>In Dielmo and Ndiop, the incidence of malaria has decreased, but fever syndromes remain frequent. Among the 1036 inhabitants included in the cohort, a total of 1,129 episodes of fever were reported. …”

Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx by Yang Guo (399435)

“…The results of alpha diversity revealed a reduction in the Chao1 index (SMD = −0.40, 95% CI = −0.76 to −0.05), Observed species (SMD = −0.50, 95% CI = −0.89 to −0.12) and Shannon index (SMD = −0.27, 95% CI = −0.47 to −0.08) of the gut microbiota in patients with OSA. …”

Policy attention to climate change impacts, adaptation and vulnerability: a global assessment of National Communications (1994–2019) by Robbert Biesbroek (5906696)

“…Based on 612 documents, we find impact topics dominate policy attention (>50% of the topics), but this has decreased in recent periods. …”

Aβ-induced dispersal of Homer1b and Shank1 clusters does not depend upon protein degradation. by Francesco Roselli (211670)

“…CHX+Aβ and CHX alone). For each condition, 8–12 neurons from 3–4 replicate experiments were considered (N = 8–12), and at least 50 synapses on each neuron were evaluated (average, n = 500 puncta/condition). …”