shRNA-mediated knockdown of <i>Tsc2</i> expression in 3T3-L1 preadipocytes leads to enhanced mTORC1-dependent adipocyte differentiation. by Hui H. Zhang (262186)

“…<p>(A) 3T3-L1 preadipocytes with stable shRNA-mediated knockdown of <i>Tsc2</i> expression display elevated basal mTORC1 signaling and attenuation of insulin-stimulated Akt phosphorylation. 3T3-L1 preadipocytes stably expressing shRNAs targeting <i>Tsc2</i> (shTsc2), or firefly luciferase (shLuc) as a control, were serum-starved for 16 h and, where indicated, were pretreated with rapamycin for 15 min prior to stimulation with 100-nM insulin for 15 min. …”

Figure 4 from P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids by Bernat Navarro-Serer (21450536)

“…<p>Knockdown of P4HA1 decreases invasion in PDAC PDOs in hypoxia. <b>A,</b> Expression level of P4HA1 measured by qRT-PCR. …”

Muscle oxygenation in vastus lateralis and gastrocnemius during incremental running exercise: effect of exercise intensity, VO2max, sex and age by Hugo Kerhervé (618369)

“…The aim of this study was to describe the effect of exercise intensity, maximum oxygen utilisation (V ̇O_2MAX), sex and age on vastus lateralis (VL) and gastrocnemius (Gn) muscle oxygenation measured using near-infrared spectroscopy (NIRS) during incremental running exercise to exhaustion, in a participant group having a large range of V ̇O_2MAX.…”

Image11_Alpiniae oxyphylla fructus extract promotes longevity and stress resistance of C. elegans via DAF-16 and SKN-1.TIFF by Man Xiao (556153)

“…<p>Background:Alpiniae Oxyphylla Fructus (AOF) is Traditional Chinese medicine and a dietary supplements for centuries, which posseses cardiotonic, neuroprotective, antioxidant, warming the kidney and nourish the spleen, these biological fuction is related to potential anti-aging properties. …”

Image14_Alpiniae oxyphylla fructus extract promotes longevity and stress resistance of C. elegans via DAF-16 and SKN-1.TIFF by Man Xiao (556153)

“…<p>Background:Alpiniae Oxyphylla Fructus (AOF) is Traditional Chinese medicine and a dietary supplements for centuries, which posseses cardiotonic, neuroprotective, antioxidant, warming the kidney and nourish the spleen, these biological fuction is related to potential anti-aging properties. …”

Image2_Alpiniae oxyphylla fructus extract promotes longevity and stress resistance of C. elegans via DAF-16 and SKN-1.TIF by Man Xiao (556153)

“…<p>Background:Alpiniae Oxyphylla Fructus (AOF) is Traditional Chinese medicine and a dietary supplements for centuries, which posseses cardiotonic, neuroprotective, antioxidant, warming the kidney and nourish the spleen, these biological fuction is related to potential anti-aging properties. …”

Data_Sheet_2_Neck Chamber Technique Revisited: Low-Noise Device Delivering Negative and Positive Pressure and Enabling Concomitant Carotid Artery Imaging With Ultrasonography.zip by Rafał Seredyński (11522512)

“…Second, we used small, 3D-printed cups positioned over the carotid sinuses instead of cumbersome neck collar to improve subject comfort and to test feasibility of tracking the pressure-induced changes in carotid artery with ultrasonography.</p><p>Methods: Five healthy, non-smoking, normal-weight subjects aged 29 ± 3 years (mean ± SD) volunteered for the study. …”

Data_Sheet_1_Neck Chamber Technique Revisited: Low-Noise Device Delivering Negative and Positive Pressure and Enabling Concomitant Carotid Artery Imaging With Ultrasonography.PDF by Rafał Seredyński (11522512)

“…Second, we used small, 3D-printed cups positioned over the carotid sinuses instead of cumbersome neck collar to improve subject comfort and to test feasibility of tracking the pressure-induced changes in carotid artery with ultrasonography.</p><p>Methods: Five healthy, non-smoking, normal-weight subjects aged 29 ± 3 years (mean ± SD) volunteered for the study. …”

Video_1_Neck Chamber Technique Revisited: Low-Noise Device Delivering Negative and Positive Pressure and Enabling Concomitant Carotid Artery Imaging With Ultrasonography.MOV by Rafał Seredyński (11522512)

“…Second, we used small, 3D-printed cups positioned over the carotid sinuses instead of cumbersome neck collar to improve subject comfort and to test feasibility of tracking the pressure-induced changes in carotid artery with ultrasonography.</p><p>Methods: Five healthy, non-smoking, normal-weight subjects aged 29 ± 3 years (mean ± SD) volunteered for the study. …”

Video_2_Neck Chamber Technique Revisited: Low-Noise Device Delivering Negative and Positive Pressure and Enabling Concomitant Carotid Artery Imaging With Ultrasonography.MOV by Rafał Seredyński (11522512)

“…Second, we used small, 3D-printed cups positioned over the carotid sinuses instead of cumbersome neck collar to improve subject comfort and to test feasibility of tracking the pressure-induced changes in carotid artery with ultrasonography.</p><p>Methods: Five healthy, non-smoking, normal-weight subjects aged 29 ± 3 years (mean ± SD) volunteered for the study. …”

EDA-FN diminishes liver fibrosis. by Stephanie Rossnagl (553093)

“…<p>(A–B) Fibrosis was increased in cKO animals, as evidenced by enhanced matrix accumulation, shown using picro-sirius red staining of the matrix (A, middle), collagen I staining in red (A, right) (Bars represent 100 μm), and quantification of collagen biochemically (B, left), as well as by impaired liver function (alanine transaminase [ALT] is shown in B, right), <i>n</i> = 13/10/15/14 for collagen and 17/16/15/12 for ALT in three experiments. …”

Image_2_The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma.jpg by Erik Ladomersky (6517835)

“…<p>Background: Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and is associated with a median overall survival (mOS) of 16–21 months. …”

Effect of hematopoietic S1P lyase deficiency on T-cell proliferation and migration. by Martine Bot (585909)

“…<p>(A) The mitotic response of T cells isolated from <i>Sgpl1^−/−</i> chimeras to αCD3/αCD28 (2 µg/mL) or ConA (2 µg/mL) challenge is markedly decreased compared to <i>Sgpl1^+/+</i> transplanted mice (n = 8 per group). …”

Image_1_The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma.jpg by Erik Ladomersky (6517835)

“…<p>Background: Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and is associated with a median overall survival (mOS) of 16–21 months. …”

Image_8_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”

Image_2_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”

Image_9_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”

Image_6_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”

Image_3_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”

Image_4_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”