P-TEFb and the Super Elongation Complex (SEC) display similar phenotypes. by Olle Dahlberg (645665)

“…Columns show average values in 2–4h embryos with S.E.M. (n = 5–6) and control values were set to 100%. Relative expression was normalized to a mean of four reference genes (<i>beta-tubulin</i>, <i>GAPDH</i>, <i>RpL32</i>, and <i>28SrRNA</i>). …”

Molecular analyses of the C-terminal CRAF variants associated with cardiomyopathy reveal their opposing impacts on the active conformation of the kinase domain by Saeideh Nakhaei-Rad (3390110)

“…However, the underlying mechanistic details by which these mutations increase or decrease kinase activity remain elusive. Therefore, we applied molecular dynamic simulation to investigate the impacts of these point mutations on the conformation of the CRAF kinase domain. …”

DataSheet1_SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds.xlsx by Nirmal Vadgama (3474668)

“…We identified a splice site variant (rs2285666) associated with increased ACE2 expression with an overrepresentation in SARS-CoV-2 positive patients relative to 100KGP controls (p = 0.015), and in hospitalised European patients relative to outpatients in intra-ethnic comparisons (p = 0.029). …”

Table 1_Dupilumab relieves pruritus both in uremic pruritus and in atopic dermatitis with chronic kidney disease: a retrospective real-world study.docx by Qian Wang (32718)

“…The percentages of UP patients who achieved PP-NRS ≥ 4-point improvement and 5D-IS ≤ 10-point at week 4, 12, and 16 did not significantly differ from those of AD patients with CKD (p > 0.05). …”

Data_Sheet_1_Prognosis and Risk Factors of Radiation-Induced Lymphopenia in Early-Stage Lung Cancer Treated With Stereotactic Body Radiation Therapy.zip by Qianqian Zhao (712029)

“…Stepwise multivariate linear regression, which incorporated all of the significantly clinical variables and SBRT-related parameters in univariate analysis, revealed that lower pre -SBRT TLC (P < 0.001), higher heart V5 (P = 0.002), and longer total beam-on time (TBT) (P = 0.001) were the independent risk factors for decrease in post-SBRT TLC. …”

Image_1_Prognosis and Risk Factors of Radiation-Induced Lymphopenia in Early-Stage Lung Cancer Treated With Stereotactic Body Radiation Therapy.tif by Qianqian Zhao (712029)

“…Stepwise multivariate linear regression, which incorporated all of the significantly clinical variables and SBRT-related parameters in univariate analysis, revealed that lower pre -SBRT TLC (P < 0.001), higher heart V5 (P = 0.002), and longer total beam-on time (TBT) (P = 0.001) were the independent risk factors for decrease in post-SBRT TLC. …”

High Intensity Exercise in Multiple Sclerosis: Effects on Muscle Contractile Characteristics and Exercise Capacity, a Randomised Controlled Trial by Inez Wens (635807)

“…</p><p>Results</p><p>Compared to SED, 12 weeks of high intensity exercise increased mean fiber CSA (H_ITR: +21±7%, H_CTR: +23±5%). …”

Table 1_Imeglimin may affect hemoglobin A1c accuracy via prolongation of erythrocyte lifespan in patients with type 2 diabetes mellitus: insights from the INFINITY clinical trial.d... by Takeshi Osonoi (1951555)

“…</p>Results<p>The change in hemoglobin concentration at 6 months was not statistically significant (mean ± SD: −0.2 ± 0.9 g/dL; p = 0.23). While HbA1c and GA decreased and 1,5-AG increased one month after imeglimin initiation, GA and 1,5-AG showed rapid changes compared to the gradual decrease in HbA1c. …”

Identification of host factors required for HCV RNA replication or IRES-mediated translation. by Qisheng Li (522711)

“…B–H) All values were normalized to siNT (as 1), and represent the mean ± SD, n = 5 (B, C, F–H) or 3 (D, E). The asterisks indicate statistically significant differences (*p<0.05; **p<0.01); NS, not significant.…”

Effect of the two mind-sets induction on the nociceptive S2-ER% oscillatory activity at Cz. by Elia Valentini (658405)

“…The difference peaked at 262 ms (range: 239–290 ms) and 5 Hz (3.3–6.8 Hz).</p>…”

Evaporative cooling system for gestating and lactating sows: a systematic review by Melissa Fabíola dos Santos Alves Mendes (10441260)

“…It can be concluded that the use of evaporative cooling system promotes increase in feed intake per lactating sow, decrease in weight loss in lactation, increase of weight of piglets at weaning, temperature reduction of the barns and decrease of the respiratory rate of the sows. …”

Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden... by Matej Stuhec (5643284)

“…</p>Results<p>The study included 100 inpatients with a mean age of 78.1 years (SD = 6.78). …”

Changing demographics of visceral leishmaniasis in northeast Brazil: Lessons for the future by Iraci Duarte Lima (4915387)

“…Over time the annual incidence of VL decreased in the 0–4 years (<i>p</i><0.0001) and 5–9 (p <0.0001) age groups, but increased in ages 20–39 (p<0.001) and >40 years (p<0.0001). …”

Dynamics and Collapse in a Power System Model with Voltage Variation: The Damping Effect - Fig 4 by Jinpeng Ma (3342755)

“…Hence with the increase of <i>M</i>, the coexistence region increases gradually and the dominant stable fixed point region decreases correspondingly. This indicates that smaller <i>M</i> favors the occurrence of stable fixed point.…”

Data_Sheet_1_Frequency-Specific Effects of Galvanic Vestibular Stimulation on Response-Time Performance in Parkinson's Disease.DOCX by Soojin Lee (399089)

“…We hypothesized GVS motor effects were a function of stimulation frequency, and specifically, that band-limited ms-GVS would result in better motor performance than conventionally used broadband RN-GVS.…”

Supplementary Material for: Ventilated Infants Have Increased Dead Space and Lower Alveolar Tidal Volumes during the Early versus Recovery Phase of Respiratory Distress by Zuiki M. (8114360)

“…There were significant differences between the early and recovery phases for V_d,an (mean difference in V_d,an/kg = 0.57 mL/kg; 95% confidence interval [CI], 0.38–0.77; mean difference in V_d,an/V_T = 0.10; 95% CI, 0.07–0.14) and V_A (mean difference in V_A/kg = –0.60 mL/kg; 95% CI, –0.94 to –0.27; mean difference in V_A/V_T = –0.12; 95% CI, –0.15 to –0.09), despite no difference in V_T. …”

iGP-1 is cell-permeant and inhibits mGPDH in intact presynaptic terminals. by Adam L. Orr (526725)

“…(<b>B</b>) Fluorescence of 100 µM iGP-1 in a live STHdhQ7 cell labeled with LysoTracker Red. …”

Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. by Wang, Yue

“…Logistic regression was used to examine the association. The mean age of the study population was 50·9 (sd 15·1) years. …”
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The Effects of Statin Treatment on Serum Ferritin Levels: A Systematic Review and Meta-Analysis by Jamialahmadi, Tannaz

“…The effect size was determined using weighted mean differences (WMDs) and the corresponding 95% confidence intervals (CIs). …”
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Climatology and variability of wind speeds along the southwest coast of India derived from Climate Forecast System Reanalysis winds by Abdulla, Cheriyeri Poyil

“…The study reveals significant decreasing trends in annual mean wind speeds, of the order of −2.0 to −2.5 cm·s−1·year−1, for the period 1979–2019. …”
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