DataSheet2_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet5_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet4_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet1_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

Clustered heat maps of genes involved in significant pathways identified for each major group of clustered gene expression profiles. by Joel K. Wise (240576)

“…<p>Cluster 3.0 was used to cluster the log base 2 fold-change expression values (vs. day 0 time point) of genes associated with certain significant biological pathways of interest from the three major temporal expression groupings (increased, decreased, and variable expression). …”

DataSheet_1_Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia.pdf by Xue Yi (12115359)

“…Single agent exposure induced some apoptosis but combination of 100 nM venetoclax and 100 or 300 nM of AMG-176 resulted in 40–100% cell death in baseline samples. …”

DataSheet_2_Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia.pdf by Xue Yi (12115359)

“…Single agent exposure induced some apoptosis but combination of 100 nM venetoclax and 100 or 300 nM of AMG-176 resulted in 40–100% cell death in baseline samples. …”

The strategic persistence of users. by Lingfei Wu (453300)

“…This means that a majority of users contribute to only one community. …”

Chile’s 2014 sugar-sweetened beverage tax and changes in prices and purchases of sugar-sweetened beverages: An observational study in an urban environment by Juan Carlos Caro (4707607)

“…<div><p>Background</p><p>On October 1, 2014, the Chilean government modified its previous sugar-sweetened beverage (SSB) tax, increasing the tax rate from 13% to 18% on industrialized beverages with high levels of sugar (H-SSBs) (greater than 6.25 grams [g] sugar/100 milliliters [mL]) and decreasing the tax rate from 13% to 10% on industrialized beverages with low or no sugar (L-SSBs) (less than 6.25 g sugar/100 mL). …”

Table 6_Global burden of chronic kidney disease due to hypertension attributable to dietary risks in adults aged 25 years and older: findings from the global burden of disease stud... by Lianjie Huang (21775979)

“…Background<p>Suboptimal diet remains a major threat to chronic kidney diseases (CKD) and hypertension, however, the burden of diet-attributable CKD due to hypertension (HCKD) has been poorly quantified and reported. …”

Data_Sheet_1_Dynamic electrophysiological mechanism in patients with long-standing persistent atrial fibrillation.docx by Emilio Osorio-Jaramillo (13877585)

“…However, individual zones showed a high number of quantitative changes (increase/decrease) of driver activity. …”

Data Sheet 1_Global burden of chronic kidney disease due to hypertension attributable to dietary risks in adults aged 25 years and older: findings from the global burden of disease... by Lianjie Huang (21775979)

“…Background<p>Suboptimal diet remains a major threat to chronic kidney diseases (CKD) and hypertension, however, the burden of diet-attributable CKD due to hypertension (HCKD) has been poorly quantified and reported. …”

<i>Ras</i> cells show elevated checkpoint activity in response to treatment with cytarabine, daunorubicine or etoposide. by Mona Meyer (257592)

“…<p>(A) Phosphorylation of Chk1 in response to cytarabine treatment is dose-dependent and elevated in <i>Ras</i> cells. …”

Peripheral LPS administration leads to microglial cell changes in the ONH and retina. by Konstantin Astafurov (624754)

“…“V” denotes location of the vitreous body. Arrows point to the junction between the optic nerve tissue and the sclera. …”

Characteristics of stroke patients. by Yeo Hyung Kim (10338764)

“…Higher nonhemiplegic calf circumference (OR, 0.80; 95% CI, 0.67–0.96; p = 0.02) was associated with a lower likelihood of possible sarcopenia. We conclude that tube feeding, high stroke severity, decreased nonhemiplegic calf circumference, and older age are independent risk factors for possible sarcopenia in patients with subacute stroke.…”

Combined Blockade of costimulation and adhesion pathways overcomes heterologous alloimmunity. by Jonathan M. Beus (441623)

“…Following discontinuation of therapy, all grafts failed with a median time of 34 d. (E) Mice treated with combined costimulation and adhesion blockade demonstrated a decreased frequency of KLRG1+/CD127+ CD8+ T cells relative to mice treated with costimulation blockade alone. …”

Conventional approach in programming the static nonlinearity artificially constrained the dynamic range of prostheses to an unnaturally narrow band. by Kantapon Pum Wiboonsaksakul (13794446)

“…<p>(<b>A</b>) Schematic of the VOR generation in a monkey implanted with the prosthesis. …”

Early nicotinamide administration halts proliferation of <i>Sox1</i>GFP derived neural progenitor cells. by Síle M. Griffin (4373056)

“…Nicotinamide treatment significantly reduced the percentage of GFP-expressing cells, concomitant with a decrease in the percent of EdU-labelled cells in the <i>Sox1</i>GFP-positive population (E, F). …”

Induction of ssDNA at human telomeres. by Remco P. Crefcoeur (3611735)

“…Untransfected, sgControl-, and sgTelomere-transfected cells showed, respectively, 5%, 4%, and 50% colocalization. A total number of 100 cells were counted (p<0.00001).…”

Angiogenesis <i>in vitro</i> of ECs of HD2. by Christina Herre (12475755)

“…The knockdown group showed a persistent decrease in cell density (h, i). Control group showed positive eGFP control during the investigation period (d_GFP, e_GFP, f_GFP), whereas sh₂ displayed a reduction in fluorescent signals (g_GFP, h_GFP, i_GFP). …”