Frailty in Old Age Is Associated with Decreased Interleukin-12/23 Production in Response to Toll-Like Receptor Ligation by Nathalie Compté (418458)

“…In contrast, poor nutritional status and frailty in subjects >75 years were associated with decreased IL-12p70 and IL-23 production. By intracytoplasmic staining, we confirmed that production of IL-12/23p40 by conventional dendritic cells (DCs) upon TLR ligation was decreased in frail patients. …”

Adiposity is increased and osteoblast-occupied bone surface is decreased within the external fracture callus during late stage healing in HFD-fed mice. by Matthew L. Brown (431187)

Multivariable Linear Regression Model of the Residents P-V Fit score^a. by Yaotian Fan (5917766)

Subjects:

miR-100 decreases tumor size. by Bahauddeen M. Alrfaei (484859)

RA increases S100β+ and decreases peripherin+ cell prevalence while EDN3 decreases S100β+ cell prevalence. by Jonathan M. Gisser (456149)

“…(A) The proportion of S100β+ cells was enriched by RA and decreased in response to EDN3 (B) RA increased, and EDN3 decreased the fraction of proliferating S100β+ cells. …”

Decreased striatal Drd1 mRNA expression during the early, but not late, phase of motor skill learning. by Yu Qian (153240)

GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

The fraction of predicted heterozygotes that are set to “No Call” by RHA decreases as the size of the heterozygote cluster increases. by Orna Mizrahi-Man (42539)

FoxO3a-dependent mechanism of miR-150-5p in regulating pyroptosis in ox-LDL-stimulated RAW264.7 macrophages. (A-E) FoxO3a and ARC expression analyzed by (A-C) RT-qPCR and (D-E) Wes... by Ping-yu Cai (12389929)

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

(R)-albuterol decreases cytokine mRNA levels in activated T cells by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”

Five-hours-old clots were subjected to scanning electron microscopy. by Jan Víteček (11434774)

Fibrosis markers. by Dwight D. Harris (14484648)

Immunoblotting for TGF-beta, alpha-actinin, MMP-13, and mTOR. by Dwight D. Harris (14484648)

Immunoblotting for JAK, STAT, and SMAD. by Dwight D. Harris (14484648)

Immunoblotting for insulin sensitivity markers. by Dwight D. Harris (14484648)

Immunoblotting FOXO1 and insulin receptors. by Dwight D. Harris (14484648)