Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

“…K562 and K562-R cells were treated with 9nM bortezomib and 8nM BI 2536 for 60h, followed by the detection of Bcr-Abl and phosphorylated STAT5. The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”

Decreased neutrophil levels in HIF^C mice correlates to decreased production of CXCL1 and not migration defects. by Kelly M. Shepardson (404375)

(R+S) and (R)-albuterol decrease NF-κB activity by Marcela A Ferrada (41716)

“…After transfection, (R)-albuterol (R), (S)-albuterol (S), or racemic albuterol (R+ S) were added to cells pre-activated with (ConA, 5 μg/ml) and (PMA, 100 ng/ml) (CP) and then treated with (R)-, (S)-, or (R+S)-albuterol (Fig. 6). …”

Treatment of serine protease inhibitor (AEBSF) in the uterus decreases the number of sperm in the oviduct. by Shuai Li (65944)

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

“…Endogenous Beclin 1 ubiquitination level is decreased in Nedd4 siRNA-transfected rats (t_1,6 = 5.78, <i>p</i> = 0.001). …”

The GmNN1/FT2a-GmNFYA-C-GmENOD40 module regulates soybean nodulation. by Xinxin Li (281237)

Tumor volume decreases with increasing <i>Salmonella</i> dosage. by Robert A. Kazmierczak (3140379)

Effect of decreased endogenous betaglycan expression on metanephric development and glomerulogenesis. by Kenneth A. Walker (280683)

5-HT supplementation inhibits mitophagy. by Li Gao (131516)

Identification of metabolites with cell type-specific-dynamics reveals the amino acid class as highly conserved in hiPSC and hNSC and that most of the cell type-specific amino acid... by João Vasconcelos e Sá (8721594)

PEITC activates leptin signaling in differentiated SH-SY5Y cells. by Miho Yagi (5921252)

Decrease of p38 MAPK phosphorylation in HL60 and KG1a cells exposed to 5-Fluorouridine (FUrd) after cell pretreatment with p38 MAPK pathway inhibitor SB202190. by Sabine Matou-Nasri (2938941)

ABCC3 overexpression decreases the retention of anti-cancer agents. by Sai A. Balaji (1452556)

(R)-albuterol decreases cytokine protein levels in activated T cells by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”

(R)-albuterol decreases cytokine levels in activated murine splenocytes by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol (R), (S)-albuterol (S) or racemic albuterol (R + S) at a dose (10M) were added to murine splenocytes pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP), (Fig 3 A, B). …”

Establishment of PANC-1 clone cells. by Noriko Kawai (6694010)

Dexamethasone decreases PGC-1α protein expression and transcription. by Jill A. Rahnert (2872766)

“…<p>(A) Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased PGC-1α protein expression (p = 0.01). n = 3/treatment from 3 experiments. …”

Dexamethasone decreases CRTC1 and CRTC2 nuclear localization. by Jill A. Rahnert (2872766)

“…<p>Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased (A) total CRTC1 (p = 0.004 and CRTC2 protein (p = 0.0007). n = 9/treatment from 3 experiments. …”

Knockdown of ABCG2 in PANC-1 clone cells increases 5-ALA staining. by Noriko Kawai (6694010)

Expression of ABC transporter genes. by Noriko Kawai (6694010)