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we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
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37581
Data_Sheet_1_Inhibition of Nitric Oxide Production in Activated Macrophages Caused by Toxoplasma gondii Infection Occurs by Distinct Mechanisms in Different Mouse Macrophage Cell L...
Published 2018“…Deletion of a number of previously defined virulence factors including ROP kinases that disrupt innate immune factors, TgIST which blocks STAT1 activation, as well as the secretory trafficking proteins ASP5 and MYR1, did not alter the phenotype of decreased NO production. …”
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37582
Data_Sheet_1_Biochemical, Metabolomic, and Genetic Analyses of Dephospho Coenzyme A Kinase Involved in Coenzyme A Biosynthesis in the Human Enteric Parasite Entamoeba histolytica.P...
Published 2018“…However, the metabolic and physiological roles of E. histolytica DPCK remain elusive. In this study, we took biochemical, reverse genetic, and metabolomic approaches to elucidate role of DPCK in E. histolytica. …”
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37583
Spiroacetals in the Colonization Behaviour of the Coffee Berry Borer: A ‘Push-Pull’ System
Published 2014“…Elucidating the effects of other spiroacetals released by coffee berries is critical to understanding their chemo-ecological roles in the host discrimination and colonization process of the coffee berry borer, and also for their potential use in the management of this pest. Here, we show that the coffee berry spiroacetals frontalin and 1,6-dioxaspiro [4.5] decane (referred thereafter as brocain), are also used as semiochemicals by the coffee berry borer for host colonization. …”
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37584
Table_1_A Pilot Study on Serial Nerve Ultrasound in Miller Fisher Syndrome.DOCX
Published 2020“…</p><p>Methods: All MFS patients (n = 5) and healthy controls (n = 18), underwent a standardized sonographic protocol that evaluated nerve sizes of facial, large arm and leg nerves, and spinal nerve roots. …”
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37585
Supplementary Material for: Role of melatonin in intestinal mucosal injury induced by chronic restraint stress in mice
Published 2025“…Results: Mice subjected to restraint stress presented elevated CORT and NE levels of 141.41% and 151.24%, respectively, and a decreased plasma MT content of 37.12%. Consistent with the decrease in MT levels, we observed a reduction in antioxidant ability and autophagic proteins and increased apoptotic protein levels in the gut, resulting in injury to the intestinal mucosa, which manifested as reductions in the villus height and the V/C ratio; the number of goblets; the number of mast and PCNA-positive cells; and the expression of tight junction proteins (ZO-1, occludin and claudin-1). …”
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37586
Depletion of White Adipose Tissue in Cancer Cachexia Syndrome Is Associated with Inflammatory Signaling and Disrupted Circadian Regulation
Published 2014“…Mice bearing the C26 tumour exhibited reduced adipose mass, elevated adipose tissue lipolysis and a 5-fold increase in plasma levels of free fatty acids. …”
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37587
Table_1_Cyclophosphamide Regulates N6-Methyladenosine and m6A RNA Enzyme Levels in Human Granulosa Cells and in Ovaries of a Premature Ovarian Aging Mouse Model.DOC
Published 2019“…CTX significantly inhibited the expression levels of RNA demethylase FTO in a time- and concentration-dependent manner but not ALKBH5. The expression levels of RNA effectors were reduced by CTX in a time- and concentration-dependent manner. …”
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37588
Table 1_Antimicrobial susceptibility profiles of commensal Clostridium perfringens isolates from chickens in Hungarian poultry farms between 2022 and 2023.docx
Published 2025“…</p>Methods<p>In this study, we aimed to assess the antibiotic susceptibility of commensal Clostridium perfringens (C. perfringens) strains (n = 146) isolated from largescale poultry farms in Hungary, using minimum inhibitory concentration (MIC) determinations. …”
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37589
siRNA Silencing of Proteasome Maturation Protein (<em>POMP</em>) Activates the Unfolded Protein Response and Constitutes a Model for KLICK Genodermatosis
Published 2012“…<div><p>Keratosis linearis with ichthyosis congenita and keratoderma (KLICK) is an autosomal recessive skin disorder associated with a single-nucleotide deletion in the 5′untranslated region of the proteasome maturation protein (<em>POMP</em>) gene. …”
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37590
Atmospheric Mercury Outflow from China and Interprovincial Trade
Published 2018“…Chinese interprovincial trade promotes the transfer of atmospheric outflow from the eastern terrestrial boundary (−6.4 Mg year<sup>–1</sup>) to the western terrestrial boundary (+4.5 Mg year<sup>–1</sup>) and a net decrease in the atmospheric outflow for the whole boundary, reducing the chance of risks to foreign countries derived from transboundary Hg pollution from China. …”
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37591
Facile Fabrication of Superhydrophobic and Magnetic Poly(lactic acid) Nonwoven Fabric for Oil–Water Separation
Published 2020“…The fabrication of an eco-friendly superhydrophobic material for oil–water separation is of important theoretical and practical significance. Herein, we proposed a facile method to fabricate a superhydrophobic and magnetic poly(lactic acid) (SMPLA) nonwoven fabric. …”
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37592
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37593
Image_8_Improved Chloride Ion Sensing Performance of Flexible Ag-NPs/AgCl Electrode Sensor Using Cu-BTC as an Effective Adsorption Layer.jpeg
Published 2019“…<p>We designed the flexible chloride ion selective sensor that directly monitors electrochemical reactions of chloride ions without using a reference electrode. …”
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37594
Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)<sup>†</sup>
Published 2003“…We have investigated conformational transitions in the Klenow fragment polymerase reaction by stopped-flow fluorescence using DNA substrates containing the fluorescent reporter 2-aminopurine (2-AP) on the template strand, either at the templating position opposite the incoming nucleotide (designated the 0 position) or 5‘ to the templating base (the +1 position). …”
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37595
Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)<sup>†</sup>
Published 2003“…We have investigated conformational transitions in the Klenow fragment polymerase reaction by stopped-flow fluorescence using DNA substrates containing the fluorescent reporter 2-aminopurine (2-AP) on the template strand, either at the templating position opposite the incoming nucleotide (designated the 0 position) or 5‘ to the templating base (the +1 position). …”
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37596
Polyheteroaryl Oxazole/Pyridine-Based Compounds Selected in Vitro as G‑Quadruplex Ligands Inhibit Rock Kinase and Exhibit Antiproliferative Activity
Published 2018“…Heptaheteroaryl compounds comprised of oxazole and pyridine units (TOxaPy) are quadruplex DNA (G4)-interactive compounds. Herein, we report on the synthesis of parent compounds bearing either amino side chains (TOxaPy-1–5) or featuring an isomeric oxazole-pyridine central connectivity (iso-TOxapy, iso-TOxapy 1–3) or a bipyridine core (iso-TOxabiPy). …”
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37597
Table_2_Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling.docx
Published 2023“…Furthermore, we identified the elevation of two sterols (Lan and Chol), and the reduction of one corticoid (11-DeoxyF) and two progestins (5α-DHP and 11β-OH-Prog) in patients.…”
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37598
Image_1_The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction.PDF
Published 2018“…It is generally believed that Aβ oligomers are the neurotoxic species and their levels in the AD brain correlate with the severity of dementia suggesting that they play a critical role in the pathogenesis of the disease. Here, we show that the incubation of differentiated human neuroblastoma cells (SHSY5Y) with freshly prepared Aβ42 oligomers initially resulted in oxidative stress and subtle nucleolar stress in the absence of DNA damage or cell death. …”
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37599
Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces
Published 2023“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10<sup>5</sup>-fold decrease in the attachment of bacteria from urine. …”
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37600
Putative Effect of Aquifer Recharge on the Abundance and Taxonomic Composition of Endemic Microbial Communities
Published 2015“…Bacterial abundance ranged from 5.0 × 10<sup>4</sup> to 1.4 × 10<sup>7</sup> cells ml<sup>-1</sup> before the addition of synthetic wastewater. …”