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37781
Data Sheet 1_Association of SGLT2 inhibitors with post-ablation atrial fibrillation recurrence in individuals with heart failure or type 2 diabetes mellitus: a systematic review an...
Published 2025“…</p>Methods<p>We carried out a structured search of PubMed, Embase, and the Cochrane Library from database launch through August 17, 2025. …”
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37782
Image_6_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.TIF
Published 2021“…Also, hsa-miR-4278 and hsa-miR-324-5p, two potential miRNA targets of CLEC4s, were uncovered. …”
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37783
Image_1_Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.TIF
Published 2021“…Empagliflozin has emerged as an agent with weight-loss potential in clinical and in vivo studies, but the mechanisms underlying its effect are not fully understood. Here, we investigated whether empagliflozin could induce WAT browning and mitochondrial alterations in KK Cg-Ay/J (KKAy) mice, and explored the mechanisms of its effects.…”
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37784
Data Sheet 1_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv
Published 2025“…Gene expression was associated with immune cell infiltration: HCM samples showed increased CD4+ T cells and M0 macrophages but decreased M2 macrophages and neutrophils. The ceRNA network comprised 5 mRNAs, 40 miRNAs, and 152 lncRNAs. …”
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37785
Table_1_Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells.XLSX
Published 2021“…</p>Results<p>A total of 3,963 differentially expressed genes (DEGs) related to doxorubicin resistance were identified, including dramatically up-regulated MT1E, GSTP1, LDHB, significantly down-regulated TFF1, UBB, DSCAM-AS1, and histone-modifying enzyme coding genes HDAC2, EZH2, PRMT5, etc. By integrating with transcriptomic datasets, we identified 18,228 DARs in MCF7-DR cells compared to control, which were positively correlated with their nearest DEGs (r = 0.6). …”
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37786
DataSheet_2_A Mendelian analysis of the relationships between immune cells and breast cancer.pdf
Published 2024“…Utilizing publicly accessible genetic data, we investigated causal connections between 731 immune cells and the occurrence of breast cancer. …”
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37787
Table_3_Preoperative Fasting C-Peptide Acts as a Promising Predictor of Improved Glucose Tolerance in Patients With Acromegaly After Transsphenoidal Surgery: A Retrospective Study...
Published 2019“…</p><p>Methods: We retrospectively reviewed 64 patients who received transsphenoidal surgery for acromegaly. …”
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37788
Data_Sheet_1_Duchenne Muscular Dystrophy With Low Acidic α-Glucosidase Activity: Two Case Reports and Literature Review.ZIP
Published 2022“…Background<p>Pompe disease is usually considered in children with elevated creatine kinase (CK) levels and decreased acidic α-glucosidase (GAA) enzyme activity. …”
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37789
Image_1_The Effect of Abnormal Reproductive Tract Discharge on the Calving to Conception Interval of Dairy Cows.TIFF
Published 2019“…<p>Prolonged calving-to-conception interval (CCI) can increase economic loss in cattle. We investigated the effect of post-calving abnormal reproductive tract discharge (ARTD) on CCI in dairy cows and quantified the relationship of ARTD and associated risk factors with CCI. …”
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37790
Image_8_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.TIF
Published 2021“…Also, hsa-miR-4278 and hsa-miR-324-5p, two potential miRNA targets of CLEC4s, were uncovered. …”
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37791
Image_2_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.TIF
Published 2021“…Also, hsa-miR-4278 and hsa-miR-324-5p, two potential miRNA targets of CLEC4s, were uncovered. …”
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37792
Table1_A Mendelian randomization study for drug repurposing reveals bezafibrate and fenofibric acid as potential osteoporosis treatments.docx
Published 2023“…</p><p>Results: The first step MR analysis found that the higher expression of four genes (HMGCR, NPC1L1, PCSK9 and PPARG) was significantly associated with a lower LDL-C level. The genetically decreased LDL-C level mediated by the PPARG was significantly associated with increased FN-BMD (BETA = −1.38, p = 0.001) and LS-BMD (BETA = −2.07, p = 3.35 × 10<sup>−5</sup>) and was marginally significantly associated with FA-BMD (BETA = −2.36, p = 0.008) and reduced fracture risk (OR = 3.47, p = 0.008). …”
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37793
Data_Sheet_1_Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells.docx
Published 2021“…</p>Results<p>A total of 3,963 differentially expressed genes (DEGs) related to doxorubicin resistance were identified, including dramatically up-regulated MT1E, GSTP1, LDHB, significantly down-regulated TFF1, UBB, DSCAM-AS1, and histone-modifying enzyme coding genes HDAC2, EZH2, PRMT5, etc. By integrating with transcriptomic datasets, we identified 18,228 DARs in MCF7-DR cells compared to control, which were positively correlated with their nearest DEGs (r = 0.6). …”
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37794
Table_1_Preoperative Fasting C-Peptide Acts as a Promising Predictor of Improved Glucose Tolerance in Patients With Acromegaly After Transsphenoidal Surgery: A Retrospective Study...
Published 2019“…</p><p>Methods: We retrospectively reviewed 64 patients who received transsphenoidal surgery for acromegaly. …”
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37795
Image_4_CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment.TIF
Published 2021“…Also, hsa-miR-4278 and hsa-miR-324-5p, two potential miRNA targets of CLEC4s, were uncovered. …”
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37796
Data Sheet 3_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv
Published 2025“…Gene expression was associated with immune cell infiltration: HCM samples showed increased CD4+ T cells and M0 macrophages but decreased M2 macrophages and neutrophils. The ceRNA network comprised 5 mRNAs, 40 miRNAs, and 152 lncRNAs. …”
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37797
'Plan-B': Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes
Published 2025“…</p><p dir="ltr"><b>Methods:</b> We solicited feedback from individuals with lived experience and/or professionals in the HBV field, reaching out through social media, conferences, professional networks. …”
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37798
Ototopical drops containing a novel antibacterial synthetic peptide: Safety and efficacy in adults with chronic suppurative otitis media
Published 2020“…We considered the synthetic antimicrobial and anti-biofilm peptide P60.4Ac to be an interesting candidate because it also displays anti-inflammatory activities including lipopolysaccharide-neutralizing activity. …”
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37799
Table_3_Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells.XLSX
Published 2021“…</p>Results<p>A total of 3,963 differentially expressed genes (DEGs) related to doxorubicin resistance were identified, including dramatically up-regulated MT1E, GSTP1, LDHB, significantly down-regulated TFF1, UBB, DSCAM-AS1, and histone-modifying enzyme coding genes HDAC2, EZH2, PRMT5, etc. By integrating with transcriptomic datasets, we identified 18,228 DARs in MCF7-DR cells compared to control, which were positively correlated with their nearest DEGs (r = 0.6). …”
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37800
Data_Sheet_1_The Spring Festival Is Associated With Increased Mortality Risk in China: A Study Based on 285 Chinese Locations.docx
Published 2022“…Pre-Spring Festival was significantly associated with decreased mortality risk (ER: −1.58%, 95%CI: −3.09% to −0.05%), and mid-Spring Festival was unrelated to mortality risks, while post-Spring Festival was significantly associated with increased mortality risk (ER: 3.63%, 95%CI: 2.15–5.12%). …”