Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …”

The radial water maze latency [s (mean ± SEM)] and number of errors (mean ± SEM) of proton irradiated and control rats on Day 1 and Day 2. by Michael T. Williams (357796)

Mean productivity change in all 5 countries. by Wasi Ul Hassan Shah (8605236)

Characteristics of study participants. by Uzair Abbas (18517982)

Subjects:

Treatment with low doses of GI254023X causes a mild decrease in ADAM10 surface expression that correlates with a marked impairment of HCV infectivity. by Belén Carriquí-Madroñal (17396512)

Cumulative distribution of EQ-5D-3L utilities decreasingly ordered before and after the onset of cutaneous leishmaniasis symptoms. by Janaína de Pina Carvalho (12152812)

Exploration of the connected interface (S100A1/MDM2) section in MDM2. by Deepu Dowarha (5673440)

Subjects:

Dynamic viscosity of AWOE (control, 100% dispersant, and as a function of dispersant additive fraction). by Gerald F. John (7387964)

Generalized estimating equation (GEE) model results on the influence of weekly weather conditions and air quality on weekly visitation to federal parks and protected areas (PPA), i... by Kira Minehart (21029571)

The energy, the total number of proteins, fat, and carbohydrates of the diets per 100 g. by Fatima Dikhanbayeva (11501962)

DataSheet_1_Accelerating Decreases in the Incidences of Hepatocellular Carcinoma at a Younger Age in Shanghai Are Associated With Hepatitis B Virus Vaccination.docx by Shunzhang Yu (12340927)

“…Sero-epidemiological data from the sampling surveys during 20 years of follow-up showed that less than 1% of people undergoing HBV vaccination have a positive serum HBsAg. Consistently, the annual adjusted standardization rates (ASR) of HCC steadily fell from 33.38 and 11.65 per 100,000 for males and females in 1973 to 17.34 (-49.2%) and 5.60 (-51.9%) per 100,000 in 2014, respectively. …”

DataSheet_1_Accelerating Decreases in the Incidences of Hepatocellular Carcinoma at a Younger Age in Shanghai Are Associated With Hepatitis B Virus Vaccination.docx by Shunzhang Yu (12340927)

“…Sero-epidemiological data from the sampling surveys during 20 years of follow-up showed that less than 1% of people undergoing HBV vaccination have a positive serum HBsAg. Consistently, the annual adjusted standardization rates (ASR) of HCC steadily fell from 33.38 and 11.65 per 100,000 for males and females in 1973 to 17.34 (-49.2%) and 5.60 (-51.9%) per 100,000 in 2014, respectively. …”

ALS Variants of Annexin A11’s Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution by Aman Shihora (16529668)

“…These findings indicate a slower fibril-to-monomer exchange for these ALS variants, resulting in a decreased level of S100A6-mediated fibril dissolution. …”

Minimum, maximum, and mean horizontal and diagonal FID for the different species. Upper 95% confidence intervals were calculated from the mean. The minimum and maximum distances fo... by Estefania Velilla (22566709)

Mitigation (decreasing) scenario. by Fabio Correddu (12501799)

Hazard Ratios (HRs) and 95% CI for cancer per tertile decrease in DII, and tertile increase in MDS, at baseline in all participants (n = 100,881), men (n = 49,880), and women (n =... by Stina Bodén (3905218)

Plot of mean simulated power with 95 percentile (2.5 & 97.5%) for select DNAm differences. by Jacquelyn Y. Taylor (6386456)

S100A1 can interfere with the interaction between p53 and MDM2/MDMX. by Deepu Dowarha (5673440)

Subjects:

Animation displaying S100A1−MDM2 complex generated via the HADDOCK program. by Deepu Dowarha (5673440)

Subjects: