Rigidity−Stability Relationship in Interlocked Model Complexes Containing Phenylene-Ethynylene-Based Disubstituted Naphthalene and Benzene by Il Yoon (1862800)

“…We conclude that the reduced binding abilities are a consequence of electronic and not steric factors, originating from the extended delocalization of the aromatic system.…”

Rigidity−Stability Relationship in Interlocked Model Complexes Containing Phenylene-Ethynylene-Based Disubstituted Naphthalene and Benzene by Il Yoon (1862800)

“…We conclude that the reduced binding abilities are a consequence of electronic and not steric factors, originating from the extended delocalization of the aromatic system.…”

Dual transfection of <i>gp70</i> and <i>Mcm2</i> enhances DNA-damage-induced apoptosis in 3T3 cells. by Shinya Abe (154673)

“…Cell survival is significantly different between control cells “<i>gp70</i> (−), <i>Mcm2</i> (−)” and <i>gp70/Mcm2</i>-transfected cells “<i>gp70</i> (+), <i>Mcm2</i> (+)” (#<i>p</i><0.01). Data represent the mean and 95% CI of 3 independent experiments. (<b>C</b>) Apoptotic cell ratios in <i>gp70</i> and/or <i>Mcm2</i>-transfected 3T3 cells were determined with annexin V-staining after treatment with 1 µM doxorubicin for 24 h. …”

Loss of BIG1 causes accumulation of excitatory neurons before destination layers. by Jia-Jie Teoh (3929852)

“…<p>(A) The layering order of UL neurons (Cux1⁺) and DL neurons (Tbr1⁺) was maintained in <i>Arfgef1</i>^{<i>geo/geo</i>} but the IZ thickness reduced at E17.5. Scale bars, 200 μm. n = 3 per group. (B) At E17.5, the numbers of Tbr1⁺, Cux1⁺ and DAPI⁺ cells within a 200 μm cortical width starting from the edge of the lateral ventricle were counted. …”

Table_1_Essential oils for treating anxiety: a systematic review of randomized controlled trials and network meta-analysis.doc by Ling Tan (167819)

“…Additionally, EOs could decrease systolic blood pressure (SBP) [WMD = −6.83, (95% CI −10.53, −3.12), P < 0.001] and heart rate (HR) [WMD = −3.43, (95% CI −5.51, −1.36), P < 0.001]. …”

Presentation1_Differential lipid signaling from CD4+ and CD8+ T cells contributes to type 1 diabetes development.pptx by Tayleur D. White (19690648)

“…Introduction<p>We reported that Ca²⁺-independent phospholipase A₂β (iPLA₂β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. …”

PDIM production and export is required for induction of the macrophage type I IFN response. by Amy K. Barczak (525258)

“…<p>(A) Measurement of macrophage CCL5 production after infection with <i>Mtb</i> strains. …”

Reproducibility of the CO rebreathing technique with a lower CO dose and a shorter rebreathing duration at sea level and at 2320 m of altitude by Laura Oberholzer (9401512)

“…Its clinical application is often hindered due to the consequent rise in carboxyhemoglobin (%HbCO) and the concern of CO toxicity. We tested the reproducibility of the CO rebreathing with a CO dose of 0.5 mL/kg body mass (CO_0.5) compared to 1.5 mL/kg (CO_1.5) and when shortening the CO rebreathing protocol. …”

Physiological risk of falls, physical and aerobic capacity in community-dwelling elderly by Lygia Paccini Lustosa (4650658)

“…Results: Participated 59 elderly (71.8±5.0 ys). The mean performance in PPA was 0.4±0.4; SPPB was 10.4±1.7 and ISWT was 281±111.7 meters. …”

Changes in the four most discriminating parameters characterizing the LDF responses following the injections of increasing concentrations of ADP. by Tomasz Przygodzki (4277908)

“…<p>Each dose of ADP was injected in two consecutive boluses to the same mouse (with intervals). The values represent means ± standard deviations for normally-distributed data (AUC, A_max, T_c) and medians with interquartile ranges for the data which significantly deviated from normal distribution (V_0r); (n = 7). …”

Glucose-dependent insulinotropic peptide in the high normal range is associated with increased carotid intima-media thickness by Amra Jujić (524347)

“…</p> <p><b>Conclusion </b>In a Swedish elderly population, physiologically elevated levels of fasting GIP are associated with increased IMT_meanCCA, while GLP-1 is associated with decreased IMT_maxBulb, further emphasizing diverging cardiovascular effects of these two incretin hormones.…”

Disturbances in sleep quality in parkinsonian marmosets. by Gourav R. Choudhury (5680574)

“…(H) The total amount of time animal spent moving at night was significantly increased at 1 month. (I) The mean nocturnal activity was significantly higher at 1 month in the marmosets. …”

Closed-loop insulin therapy for people with type 2 diabetes treated with an insulin pump: a 12-week multicenter, open-label randomized controlled crossover trial by Anne-Laure Borel (444715)

Roles of varying protein and choline nutrient contents in very high fat, low protein, very low carbohydrate diet-induced hepatic steatosis. by Rebecca C. Schugar (452038)

“…Data are presented as means±SEM. <i>a</i>, significant difference compared to chow; <i>b</i>, significant difference attributable to decrease in protein content (from 10% kcal to 5% kcal) at a fixed choline content; <i>c</i>, significant difference attributable to restriction in choline content (from 5.3 g/kg to 0.3 g/kg) at a fixed protein content; by 1-way ANOVA with Tukey’s post hoc testing.…”

Effects of tPA and cilostazol on endothelial cells at 18 h after reperfusion. by Mitsunori Ishiguro (359127)

“…Western blot analysis measured the levels of claudin-5. tPA alone at 6 h decreased claudin-5 levels. …”

Metabolic parameters of mice maintained on very high fat, low protein, very low carbohydrate diets. by Rebecca C. Schugar (452038)

“…For all panels, data are presented as means±SEM. <i>a</i>, significantly different compared to chow; <i>b</i>, significant difference attributable to decrease in protein content (from 10% kcal to 5% kcal) at a fixed choline content; <i>c</i>, significant difference attributable to restriction in choline content (from 5.3 g/kg to 0.3 g/kg) at a fixed protein content; by 1-way ANOVA with Tukey’s post hoc testing.…”

Supplementary file 1_Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study.do... by Nian Jiang (1338381)

“…Additionally, we executed a battery of sensitivity and subgroup analyses to validate the robustness of our findings.…”

Evaluation of the Prevalence and Production of <i>Escherichia coli</i> Common Pilus among Avian Pathogenic <i>E. coli</i> and Its Role in Virulence by Alyssa K. Stacy (513962)

“…Avian colibacillosis is responsible for significant economic losses to the poultry industry due to disease treatment, decrease in growth rate and egg production, and mortality. …”

Table_1_Delayed Diagnosis and Treatment of Cancer Patients During the COVID-19 Pandemic in Henan, China: An Interrupted Time Series Analysis.DOCX by Changpeng Liu (1489699)

“…</p>Results<p>The observed overall monthly number of inpatient admissions decreased by 20.2% [95% confidence interval (CI), 11.7–27.2%], 78.9% (95% CI, 77.3–80.4%), and 40.9% (95% CI, 35.6–45.5%) in January, February, and March 2020, respectively, as compared with those predicted using the ARIMA model. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”