Time courses of voluntary running activity and causes of death in DCM mice. by Masami Sugihara (171797)

“…LD: mice with activity of <1 km/day before death (<i>n</i> = 12). Bars are mean±SD. *P<0.05, **P<0.01, ***P<0.001. <b><i>F.</i></b> Typical ventricular arrhythmia recorded with telemetry ECG system from a 2.5-month-old mouse with high wheel running activity. …”

Data_Sheet_1_Sulforaphane Alleviates Particulate Matter-Induced Oxidative Stress in Human Retinal Pigment Epithelial Cells.pdf by Hyunchae Sim (10984419)

“…SFN treatment increased ARPE-19 cell viability and decreased PM_2.5-induced oxidative stress in a dose-dependent manner. …”

Glucose-dependent insulinotropic peptide in the high normal range is associated with increased carotid intima-media thickness by Amra Jujić (524347)

“…</p> <p><b>Conclusion </b>In a Swedish elderly population, physiologically elevated levels of fasting GIP are associated with increased IMT_meanCCA, while GLP-1 is associated with decreased IMT_maxBulb, further emphasizing diverging cardiovascular effects of these two incretin hormones.…”

<i>Mtb</i> inside hypoxic macrophages loses acid fastness and accumulates lipid droplets. by Jaiyanth Daniel (111037)

“…Human macrophages were infected at MOI 0.1 and were incubated at 1% O₂, 5% CO₂ at 37°C. <i>Mtb</i> cells were recovered from human macrophages after 4 h infection (<b>A</b>), at 3 days (<b>B</b>) and 5 days (<b>C</b>) and stained with Auramine-O and Nile Red; <b>D</b>, Quantitation of acid-fast and neutral lipid staining <i>Mtb</i> recovered from hypoxic human macrophages (shown in <b>A</b>–<b>C</b>) indicates a decrease in acid-fastness and increase in lipid droplet staining with time. …”

Augmentation of autophagy with rapamycin protects against tumor metastasis. by Jun Yan (28467)

“…Data are presented as the mean ± S.E. of 5 mice per group. (C) Rapamycin treatment decreases p62 accumulation in the lung tissue. …”

ACh signals measured in rat mPFC by Howe et al. during the SAT. by Sahiti Chebolu (14035041)

“…(D) Left: consecutive correct reports of no signal are not expected to be associated with attentional change. Right: if a signal (and detection) means that the <i>strong</i> attentional state is occupied at the end of trial <i>t</i>−1, it may persist into trial <i>t</i>; however, if there is no signal in this next trial, then there may be a reversion back to the <i>weak</i> attentional state (i.e., a relative decrease).…”

Autism and Sensory Processing Disorders: Shared White Matter Disruption in Sensory Pathways but Divergent Connectivity in Social-Emotional Pathways by Yi-Shin Chang (606213)

“…We define white matter tracts using probabilistic streamline tractography and assess the strength of tract connectivity using mean fractional anisotropy. …”

N-Glycomic Changes in Serum Proteins in Type 2 Diabetes Mellitus Correlate with Complications and with Metabolic Syndrome Parameters by Roberto Testa (218036)

“…</p><p>Methods</p><p>We enrolled in the study 562 patients with Type 2 Diabetes Mellitus (T2DM) (mean age 65.6±8.2 years) and 599 healthy control subjects (CTRs) (mean age, 58.5±12.4 years). …”

Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing by Joshua N. Farr (799622)

“…High-throughput RNA sequencing (RNAseq), on the other hand, offers an unbiased approach to examine the entire transcriptome. Here we present an RNAseq analysis of human bone samples, obtained from iliac crest needle biopsies, to yield the first <i>in vivo</i> interrogation of all genes and pathways that may be altered in bone with aging and E therapy in humans. 58 healthy women were studied, including 19 young women (mean age ± SD, 30.3 ± 5.4 years), 19 old women (73.1 ± 6.6 years), and 20 old women treated with 3 weeks of E therapy (70.5 ± 5.2 years). …”

Including cell content predictions in the analysis of microarray data improves model fit and enhances the detection of previously-identified diagnosis-related genes in some dataset... by Megan Hastings Hagenauer (5523191)

“…<b>B:</b> We examined a series of differential expression models of increasing complexity, including a base model (M1), a standard model (M2), and three models that included cell type co-variates (M3-M5). …”

Effect of <i>OPA1</i> or <i>Mfn1</i> silencing on mitochondrial Ca²⁺ uptake in permeabilized HeLa cells. by László Fülöp (203208)

“…<p>For the transfection protocol and measurement of fluorescence see legend of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0025199#pone-0025199-g005" target="_blank">Figure 5</a>. …”

Focal Ischemic Injury with Complex Middle Cerebral Artery in Stroke-Prone Spontaneously Hypertensive Rats with Loss-Of-Function in NADPH Oxidases by Hiroshi Yao (562206)

“…<div><p>By means of introgressing a loss-of-function mutation in the <i>p22phox</i> gene from the Matsumoto Eosinophilia Shinshu (MES) rat to stroke-prone spontaneously hypertensive rats (SHRSP), we constructed the SHRSP-based congenic strain lacking the P22PHOX expression (i.e., lacking NADPH oxidases [NOX] activities) (SHRSP.MES-<i>Cyba</i>^<i>mes</i>/Izm; hereafter referred to as SP.MES). …”

Lovastatin treatment inhibits VEGFR-2 internalization. by Tong T. Zhao (361937)

“…Lovastatin treatments of 0.5, 1 and 5 µM inhibited VEGFR degradation in a dose dependant manner. …”

Table1_Retrospective Recall of Psychological Distress Experienced During the First COVID-19 Lockdown in Italy: Results From the ALT RISCOVID-19 Survey.doc by Francesca Bracone (12014342)

“…</p><p>Methods: Cross-sectional analysis on 1,880 adults (mean age 48.9 ± 14.5 years) from the web-based ALT RISCOVID-19 survey. …”

Timing of drug response by continuous volume data. by Andrea K. Bryan (188581)

“…For example, not only does a volume decrease occur following STS treatment, but there is a decrease in the population's variation. …”

Expression levels of miR199b in human cerebellum and in tumors, and the correlation with prognosis. by Livia Garzia (266719)

“…D) MiR-199b-5p expression by real-time PCR in a panel of five MB cell lines untreated or treated with 5-Aza-C (DAC−/+); the de-methylation induced miR-199b-5p transcription in two cell lines: Med8a and UW228. …”

Supplementary Material for: Randomized Control Study on Hemoperfusion Combined with Hemodialysis versus Standard Hemodialysis: Effects on Middle-Molecular-Weight Toxins and Uremic... by Zhao D. (3071592)

MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1 by Jianran Hu (427397)

“…<div><p>We have observed low expression levels of MARVELD1, a novel tumor repressor, in multiple tumors; however, its function in normal cells has not been explored. …”

BPTES and 968 attenuated CD4⁺ T cell proliferation and activation under normoxia and hypoxia. by Zeynep Sener (3146064)

“…Under hypoxia, only 968 decreased the PI significantly (Mean ± SD, n = 4). …”

Indirect Effects of COVID-19 on Maternal, Neonatal, Child, Sexual and Reproductive Health Services in Kampala, Uganda by Kirsty Le Doare (10716090)

“…We found a rise in adverse pregnancy outcomes for Caesarean sections (5%), haemorrhages related to pregnancy (51%), stillbirths (31%) and low-birth-weight (162%) and premature infant births (400%). …”