Data_Sheet_1_Identification of novel small molecule inhibitors of twin arginine translocation (Tat) pathway and their effect on the control of Campylobacter jejuni in chickens.pdf by Loïc Deblais (5620073)

“…</p>Results<p>Furthermore, we evaluated 177 SM hits (2.5 μg/mL and above) that increased the susceptibility to CuSO₄ for the inhibition of formate dehydrogenase (Fdh) activity, a Tat-dependent substrate. …”

Mutations at p53 binding sites augment PIK3CA promoter activity. by Snehal M. Gaikwad (279479)

“…Representative bioluminescent images of the mice bearing tumors of A2780-MPFT3 cells. Mouse from control and treated group exhibited specific [Fig. 5e3 (pre-treatment)] signals which did not decrease even after two treatments of cisplatin [Fig. 5e3 (post-treatment)].…”

Modulating the excitability gradient changes domino speed. by Jennifer Creaser (9427932)

“…Scale bar: 500 <i>μ</i>V, 5s. Panel <b>c</b> shows the mean recruitment time of model simulations of the network with different values of excitability gradient <i>δν</i>. …”

Schematic of experimental paradigms. by Shiva Farashahi (5018381)

“…A central yellow bar represented the probability of reward (between 0.5 and 1.0), while the peripheral arc indicated the amount of reward. …”

Study on the properties of oil-water interface after the interaction between ionized water and naphthenic acid by Qin Guowei (22155073)

“…The results show that after the action, the interfacial tension of oil and water continues to decrease, and 1/3 ionized water (salinity diluted to 1/3 of the prepared ionized water, 1253 ppm) decreases to a maximum of 50.89%, while 1/5 ionized water (752 ppm) only decreases 14.40%; the thickness of the oil-water interface film decreases with the salinity of ionized water, but the decrease increases after 1/3 ionized water. …”

RSK2 regulates cell cycle progression in response to genotoxic stress. by Han Chi Lim (439624)

“…RSK2 WT (A) and KO (B) MEFs were treated with 0.5 µM AD at various time points, and the cells were fixed and stained with propidium iodide, followed by flow cytometry analysis. …”

IL6/STAT3 modulates estrogen-induced GREB1 transcriptional activity in breast cancer cells. by Mingli Liu (304361)

“…The samples were treated with E2 as indicated before assaying for luciferase activity. As shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046410#pone-0046410-g005" target="_blank">Figure 5G</a>, STAT3-C decreases GREB1 transcription by approximately 39%. …”

MCF-DCIS clusters co-cultured with 3D HMF and with 2D HMF. by Kyung Eun Sung (467005)

“…<p>(A) MCF-DCIS clusters (red and outlines) co-cultured with 3D HMF and neutralizing HGF antibody at 0.5 μg/ml (3D HMF-HGF). …”

Actin polymerization lead to YAP de-phosphorylation and nuclear localization. by Pradeep Reddy (371909)

“…<p>A. The levels of pYAP are decreased after treatment with jasplakinolide. …”

Figure 6 by Chris Murgatroyd (373352)

“…<p>A, DZNep treatment inhibited Suz12 occupancy and Mecp2 recruitment at the <i>Avp</i> enhancer during hypothalamic-like differentiation of EB5 cells. …”

Empagliflozin Reduces Liver Fat in Diabetic and Nondiabetic Subjects by Siham Abdelgani (17756772)

Agmatine treatment reduced the gliosis activation following SCI. by Yu Mi Park (275600)

“…</b> The GFAP expressions were substantially decreased after SCI in the Agm treated group (<i>n</i> = 5) compared with the EC group (<i>n</i> = 5). …”

Table_1_Altered Urinary Amino Acids in Children With Autism Spectrum Disorders.XLSX by Aiping Liu (149453)

“…Using support vector machine modeling and receiver operating characteristic curve analysis, we identified a panel of 7 UAA indicators that discriminated between the samples from ASD and TD children (lysine, 2-aminoisobutyric acid, 5-hydroxytryptamine, proline, aspartate, arginine/ornithine, and 4-hydroxyproline). …”

Image_1_Altered Urinary Amino Acids in Children With Autism Spectrum Disorders.PNG by Aiping Liu (149453)

“…Using support vector machine modeling and receiver operating characteristic curve analysis, we identified a panel of 7 UAA indicators that discriminated between the samples from ASD and TD children (lysine, 2-aminoisobutyric acid, 5-hydroxytryptamine, proline, aspartate, arginine/ornithine, and 4-hydroxyproline). …”

Steroidogenic programme is differently regulated in the XX and XY gonads of <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> mice. by Alejo Torres-Cano (12878169)

“…<p>(A) Immunostaining for NR5A1 (red) and nuclear DAPI staining (blue), using sections of gonads from XY and XX control and <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> E14.5 mice. …”

SB-216763 inhibits the GSK-3 pathway. by Pramod K. Dash (246530)

“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”

Effects of cannabinoid receptor antagonism on pancreatic stellate cells. by Christoph W. Michalski (85727)

“…<p>(A) MTT assays after 48 hours' incubation of PSC with graded concentrations of CB1- and CB2-receptor antagonists AM251 and AM630 (p = n.s. for concentrations of 1.25, 2.5 and 5 µM). …”

PIAS1 inhibits the ability of TGFβto suppress E-cadherin promoter activity. by Stuart J. Netherton (152258)

“…Aii) Each column is the mean (± SEM, n = 5) of the percent repression of luciferase activity by TGFβ relative to that of the basal (− TGFβ) of the corresponding transfection as shown in Ai (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013971#s4" target="_blank">MATERIALS and METHODS</a>). …”

Longitudinal MRI study of changes in BTB permeability and rCBV of brain metastases. by Heling Zhou (368949)

“…All the tumors except one (yellow arrowhead) still kept BTB intact at week 4. rCBV maps were created and rCBV values of the tumors were presented in the table (<b>B</b>). <b>C.</b> A total of 32 lesions in 5 animals were seen on both scans of weeks 3 and 4. rCBV of brain metastases (solid) was initially similar to that of contralateral normal brain (open; mean  = 1.05±0.05 (se) vs. 0.96±0.04), but decreased significantly (p<0.05) and became significantly lower as compared to their contralateral normal brain in the late scan (mean  = 0.88±0.06 vs. 1.00±0.06; p<0.05).…”

Table_1_The Isolate Caproiciproducens sp. 7D4C2 Produces n-Caproate at Mildly Acidic Conditions From Hexoses: Genome and rBOX Comparison With Related Strains and Chain-Elongating B... by Sofia Esquivel-Elizondo (4438618)

“…However, this was considerably higher at 83.1 ± 0.44% when both fructose and n-butyrate (electron acceptor) were combined as a substrate. A comparison of 7D4C2 cultures with fructose and n-butyrate with an increasing pH value from 4.5 to 9.0 showed a decreasing n-caproate specificity from ∼92% at mildly acidic pH (pH 4.5-5.0) to ∼24% at alkaline pH (pH 9.0). …”