Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Astrocytes increase contact with vessels and expression of AQP4 following Mtb infection, which is decreased in cytosis⁺ animals. by Amanda S. Latham (12093638)

“…Representative images of the frontal cortex (A–D), cerebral nuclei (G–J), brain stem (M–P), thalamus (S–V), and hippocampus (Y–BB) 15 days post-infection are shown. …”

Multivariable Logistic Regression Model of the Burnout^a. by Yaotian Fan (5917766)

Subjects:

Excel file of Raw Data for Figures 2–5. by Daniel R. Ambruso (12042605)

Effect of MA-5 on sIBM myoblasts. by Yoshitsugu Oikawa (9721356)

Table_1_High Anal Canal Pressure and Rectal Washouts Contribute to the Decrease of Anal Basal Pressure After Botulinum Toxin Injections in Paediatric Patients With Chronic Constipa... by Ge Sun (332789)

“…Their median age was 20.5 (7.75–53.25) months. Anal basal pressure decreased after injection in 20 cases. …”

Image_1_High Anal Canal Pressure and Rectal Washouts Contribute to the Decrease of Anal Basal Pressure After Botulinum Toxin Injections in Paediatric Patients With Chronic Constipa... by Ge Sun (332789)

“…Their median age was 20.5 (7.75–53.25) months. Anal basal pressure decreased after injection in 20 cases. …”

Image_2_High Anal Canal Pressure and Rectal Washouts Contribute to the Decrease of Anal Basal Pressure After Botulinum Toxin Injections in Paediatric Patients With Chronic Constipa... by Ge Sun (332789)

“…Their median age was 20.5 (7.75–53.25) months. Anal basal pressure decreased after injection in 20 cases. …”

MiR-132-3p was downregulated in TGF-<i>β</i>1 stimulated Met-5A cells and miR-132-3p mimics and miR-132-3p inhibitor transfected Met-5A cells. by Yangyang Yin (14323701)

Subjects:

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

S1 Dataset - by Nelmo Jordão Manjate (16324619)

“…Our sensitivity analysis suggests that focussing on reducing medical supplies costs would be the most cost-saving strategy for governments in LMICs, particularly as international prices decrease. The cost of SARS-CoV-2 diagnosis using Ag-RDTs was three times lower than RT-PCR testing. …”

Histograms of model vertex von Mises stress values exceeding 5 MPa. by Nathan L. Wright (18389458)

Data_Sheet_5_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI study and machine-learning analysis.ZIP by Zhaoshun Jiang (7478243)

“…The algorithm performance was evaluated by a permutation test.</p>Results<p>We found significantly decreased DMN connectivity with the brain regions involved in visual processing in DNR patients than in non-DNR patients. …”

MVEC microvessel formation is restricted in hydrogels exhibiting increased stiffness or decreased concentration of adhesive peptides. by Rebecca A. Scott (488956)

“…An unpaired student’s t-test detect statistical significance, *p<0.05 for 7.5 wt% hydrogels containing 3 mM RGD relative to either (<b>A, C-F</b>) 15wt% hydrogels containing 3 mM RGD or (<b>G, I-L</b>) 7.5wt% hydrogels containing 1 mM RGD.…”

Activation, inactivation, and deactivation kinetics differ between Ca_V3.3 WT and variants as well as among the variants. by Yousra El Ghaleb (22075892)

Subjects:

GSK343 decreased viability and proliferation in human neuroblastoma PDX cells. by Laura V. Bownes (10276762)

“…Treatment with GSK343 resulted in significantly decreased migration. (D) After 24 hours of treatment with increasing concentrations of GSK343 (0, 5, 10 μM), COA3 and COA6 cells (4.0 × 10⁴) were plated in Transwell^® inserts and allowed to invade for 1 week through a Matrigel^™ layer. …”

Fig 5 - by Rajnish Prakash Singh (2847608)

Fig 5 - by Rashida Nayeem (11851764)

Scientists’ likelihood of using terminology sorted by overall decreasing likelihood ranking. by Jackie M. Getson (13190175)