AKT inhibition-mediated dephosphorylation of TFE3 promotes overactive autophagy independent of MTORC1 in cadmium-exposed bone mesenchymal stem cells by Huifeng Pi (638350)

Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity by Kota Ishikawa (689922)

“…However, the underlying mechanism remains unclear. We aimed to investigate insulin promoter DNA methylation in an over-nutrition state. …”

USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination by Arishya Sharma (397795)

Characterization of CD8⁺ T Cell Differentiation following SIVΔnef Vaccination by Transcription Factor Expression Profiling by James M. Billingsley (701555)

Data_Sheet_1_Improved Overall Survival, Relapse-Free-Survival, and Less Graft-vs.-Host-Disease in Patients With High Immune Reconstitution of TCR Gamma Delta Cells 2 Months After A... by Lia Minculescu (7299164)

“…-host disease (GVHD) in the setting of hematopoietic allogeneic stem cell transplantation (HSCT). We conducted a prospective study to assess the clinical impact of TCR γδ cell immune reconstitution on overall survival, relapse-free-survival, relapse and GVHD. …”

Differential regulation of <i>FasL</i> promoter activities in human T cells and in human colon cancer cells. by Jianming Wu (312135)

“…Data represent means ± SEM from four independent experiments. <b>B.…”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…The RT‒PCR data are presented as the means ± SDs (n = 3). Statistical significance: ns, p ≥ 0.05. …”

Cellular network estimation and characterisation of cell pairs by two distance measures. by Hiroshi Momiji (3254958)

“…A red + symbol is an outlier found above the whisker, which is defined to be q3 ± 1.5 (q3—q1), where q1 and q3 are the respective 25th and 75th percentiles. …”

Table_1_ASMT Regulates Tumor Metastasis Through the Circadian Clock System in Triple-Negative Breast Cancer.docx by FenFen Xie (9544523)

“…Emerging evidence has demonstrated that the circadian clock system regulates cell-signaling pathways critical to cancer cell proliferation, survival and metastasis, meaning that it could be a good candidate for TNBC treatment. …”

Nutrition levels regulate the activity of AMPK-TBC1D1- Rab2A axis and the subsequent the protein level of PPARγ. by Zi-Yue Chen (11986539)

“…Male mice were fed western diet for 3 months, and liver samples were then collected and analyzed by Q-PCR (random feed, <i>n</i> = 5 per group). <b>(B)</b> Immunoblot analysis of liver samples. …”

IFNγ and CXCL10 has a key role in CD20-TCB T cell recruitment. by Floriana Cremasco (5580266)

“…<p>a-b) Top: Representative histological staining of WSU DLCL2 tumors 24h post second treatment (0.5 mg/kg CD20-TCB or suitable vehicle i.v.). Bottom: Quantification of total signal intensity/mm² from histological images of vehicle <i>vs</i> CD20-TCB treatment. …”

Sirt1 expression, deletion, and testing FAA in mice lacking Sirt1 in Pomc neurons. by Dina R. Assali (5447489)

“…(H) Total high activity (walking, hanging, jumping, and rearing) observed during the duration of the 23.5h to 24h video across the duration of the experiment. …”

Data_Sheet_1_Accounting for Genetic Differences Among Unknown Parents in Bubalus bubalis: A Case Study From the Italian Mediterranean Buffalo.docx by Mayra Gómez (3239019)

“…<p>The use of genetic evaluations in the Water Buffalo by means of a Best Linear Unbiased Prediction (BLUP) animal model has been increased over the last two-decades across several countries. …”

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 <i>In Vitro</i> by Daniel M. DeLaughter (3140697)

Data_Sheet_6_P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.docx by Jiawen Zhou (2323381)

“…We found Bmi-1 deficiency destructed barrier structure, barrier function, and tight junction (TJ) in intestinal epithelium; decreased the TJ proteins; increased tumor necrosis factor α (TNF-α)–dependent barrier permeability; and up-regulated proinflammatory level of macrophages induced by intestinal microbial dysbiosis. …”

Data_Sheet_4_P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.docx by Jiawen Zhou (2323381)

“…We found Bmi-1 deficiency destructed barrier structure, barrier function, and tight junction (TJ) in intestinal epithelium; decreased the TJ proteins; increased tumor necrosis factor α (TNF-α)–dependent barrier permeability; and up-regulated proinflammatory level of macrophages induced by intestinal microbial dysbiosis. …”

Data_Sheet_1_P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.pdf by Jiawen Zhou (2323381)

“…We found Bmi-1 deficiency destructed barrier structure, barrier function, and tight junction (TJ) in intestinal epithelium; decreased the TJ proteins; increased tumor necrosis factor α (TNF-α)–dependent barrier permeability; and up-regulated proinflammatory level of macrophages induced by intestinal microbial dysbiosis. …”

Data_Sheet_2_P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.docx by Jiawen Zhou (2323381)

“…We found Bmi-1 deficiency destructed barrier structure, barrier function, and tight junction (TJ) in intestinal epithelium; decreased the TJ proteins; increased tumor necrosis factor α (TNF-α)–dependent barrier permeability; and up-regulated proinflammatory level of macrophages induced by intestinal microbial dysbiosis. …”

Data_Sheet_3_P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.docx by Jiawen Zhou (2323381)

“…We found Bmi-1 deficiency destructed barrier structure, barrier function, and tight junction (TJ) in intestinal epithelium; decreased the TJ proteins; increased tumor necrosis factor α (TNF-α)–dependent barrier permeability; and up-regulated proinflammatory level of macrophages induced by intestinal microbial dysbiosis. …”

DataSheet_1_State of the California Current Ecosystem in 2021: Winter is coming?.pdf by Andrew R. Thompson (9582461)

“…Off Oregon, similar to past La Niñas, larval abundances of three of six coastal species rose, while five of six southern/offshore taxa decreased in 2021. …”