DataSheet4_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Dataset for: Bronchial microdialysis monitoring of inflammatory response in open abdominal aortic aneurysm repair, an observational study by Stig Tyvold (4116607)

“…Measurements and Main Results: Samples were collected before and during cross-clamping of the aorta as well as from 0-60 min and from 60-120 min of reperfusion. The ELF levels of IL-5, IL-6, IL-13, GM-CSF, IL-2, IL-4 and TNF-α increased, whereas IL-7 decreased during reperfusion. …”

Data_Sheet_1_Graphene Oxide, a Novel Nanomaterial as Soil Water Retention Agent, Dramatically Enhances Drought Stress Tolerance in Soybean Plants.docx by Lin Zhao (92451)

“…In this study, the physiological and molecular responses to drought stress with GO treatment were examined. We discovered that the relative water content (RWC) of stems and leaves treated with GO was 127 and 128% higher than that of the WT plants, respectively. …”

Data_Sheet_1_A pharmacokinetic study on red ginseng with furosemide in equine.docx by Young Beom Kwak (17445099)

“…The C_max, AUC_0−t, and AUC_0−∞ of furosemide was significantly increased in the experimental group (p < 0.05), while the CL, V_z, and V_ss was decreased (p < 0.05, p < 0.01). …”

Protective effect of brain-derived neurotrophic factor and neurotrophin-3 overexpression by adipose-derived stem cells combined with silk fibroin/chitosan scaffold in spinal cord i... by Wen-Chen Ji (8549952)

Tailoring Ionic Conductivity of Polymeric Ionic Liquid Block Copolymers through Morphology Control by Samuel K. J. Adotey (22425591)

Image_1_Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy.pdf by Fátima Cano-Cano (10322534)

“…A hallmark of DR is the presence of retinal reactive gliosis. Here we report the beneficial effect of (S_S,1R)-1-docecylsulfiny-5N,6O-oxomethylidenenojirimycin ((Ss)-DS-ONJ), a member of the sp²-iminosugar glycolipid (sp²-IGL) family, by decreasing iNOS and inflammasome activation in Bv.2 microglial cells exposed to pro-inflammatory stimuli. …”

Presentation_1_Drebrin Isoforms Critically Regulate NMDAR- and mGluR-Dependent LTD Induction.pdf by Hiroki Yasuda (3027765)

“…In parallel, NMDA receptor (NMDAR)-dependent long-term depression (LTD) of synaptic transmission, induced by low-frequency stimulation (LFS), is dominant in the immature brain and decreases during development. Here, we report that drebrin regulates NMDAR-dependent and group 1 metabotropic glutamate receptor (mGluR)-dependent LTD induction in the hippocampus. …”

Table_2_Genome-Wide CRISPR/Cas9 Screen Identifies New Genes Critical for Defense Against Oxidant Stress in Toxoplasma gondii.docx by Yun Chen (279569)

“…In addition, several previously uncharacterized genes were identified, among which five hypothetical protein-coding genes, namely, HP1–HP5, were selected for further functional characterization. …”

Combined Effects of Ocean Warming and Acidification on Copepod Abundance, Body Size and Fatty Acid Content by Jessica Garzke (2805697)

“…Copepodite (developmental stages 1–5) and nauplii abundance were antagonistically affected by warming and acidification. …”

Longitudinal Changes in the Physical Activity of Adolescents with Anorexia Nervosa and Their Influence on Body Composition and Leptin Serum Levels after Recovery by Elzbieta Kostrzewa (474720)

“…Physical activity levels during therapy decreased for the group with initially HLPA and increased for the group with low levels of physical activity (to comparable levels). …”

DataSheet1_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Comparison of cell clustering behavior in simulations with experiments. by Rajesh Balagam (135557)

“…Probability, <i>p</i>(<i>m</i>), of finding a cell in a cluster is plotted as a function of the cluster size <i>m</i>. We use different sets of slime-trail-following mechanism parameters for non-reversing (<i>L</i>_<i>s</i> = 0.6 <i>μm</i>, <i>ε</i>_<i>s</i> = 0.5) and reversing (<i>L</i>_<i>s</i> = 11 μ<i>m</i>, <i>ε</i>_<i>s</i> = 0.2) agents. …”

<b>Glucose</b><b>-6-Phosphatase Catalytic Subunit 3 Enhances Host Resistance to Porcine Epidemic Diarrhea Virus Through Regulating </b><b>Glycolysis/Gluconeogenesis</b> by Huihui Li (22299664)

“…Transcriptomic analysis of jejunal tissues identified 5,422 differentially expressed (DE) protein-coding genes (PCGs) and 1,999 DE long non-coding RNAs (lncRNAs) between the two pig breeds. …”

Dec2 attenuates autophagy in inflamed periodontal tissues by Xiaoyan Li (9528899)

“…The expression of phosphorylated ERK was increased and levels of phosphorylated mammalian target of rapamycin (mTOR) were decreased after exposure to LPS in Dec2 siRNA transfected human PDLFs. …”

Table_4_Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring.XLSX by Lisa J. Martin (228675)

“…The LP/HC diet group also showed reduced birth and weanling weights, whereas the HP/LC offspring displayed increased weanling weight with increased adiposity beyond 5 months of age. Gene expression profiling of hypothalamus and liver revealed alterations in diverse molecular pathways by both diets. …”

Image_2_A New Enantiornithine (Aves) Preserved in Mid-Cretaceous Burmese Amber Contributes to Growing Diversity of Cretaceous Plumage Patterns.PDF by Lida Xing (309643)

“…Here, we describe a new specimen that consists of the distal extremities of both forelimbs and hindlimbs. …”

Table_6_Transcriptome in Combination Proteome Unveils the Phenylpropane Pathway Involved in Garlic (Allium sativum) Greening.XLSX by Jinxiang Wu (475283)

“…To study the mechanism of garlic greening, comprehensive full-length transcript sets were constructed. We detected the differences in greening between Pizhou (PZ) garlic and Laiwu (LW) garlic that were both stored at −2.5°C and protected from light at the same time. …”

Leveraging Vulnerabilities in Copper Trafficking for Synergistic Antifungal Activity by Catherine A. Denning-Jannace (22449392)

Presentation_1_Assessing the importance of kelp forests for small-scale fisheries under a global change scenario.pdf by Cristina Piñeiro-Corbeira (10021615)

“…Yet, even though they often support wildlife populations of high socioeconomic value, the consequences of kelp forest decline for small-scale fisheries (SSFs) have received surprisingly little attention. Here, we take the first step to fill this gap through the local ecological knowledge (LEK) of SSF fishers whose fisheries are associated with this habitat in NW Spain. …”