Image_3_Evidence of Neutralizing and Non-Neutralizing Anti-Glucosaminidase Antibodies in Patients With S. Aureus Osteomyelitis and Their Association With Clinical Outcome Following... by Shardulendra Prasad Sherchand (13108779)

“…Therefore, we first optimized an in vitro assay that quantifies recombinant Gmd lysis of the M. luteus cell wall and used it to demonstrate the 50% neutralizing concentration (NC₅₀) of a humanized anti-Gmd mAb (TPH-101) to be ~15.6 μg/ml. …”

Image_2_Evidence of Neutralizing and Non-Neutralizing Anti-Glucosaminidase Antibodies in Patients With S. Aureus Osteomyelitis and Their Association With Clinical Outcome Following... by Shardulendra Prasad Sherchand (13108779)

“…Therefore, we first optimized an in vitro assay that quantifies recombinant Gmd lysis of the M. luteus cell wall and used it to demonstrate the 50% neutralizing concentration (NC₅₀) of a humanized anti-Gmd mAb (TPH-101) to be ~15.6 μg/ml. …”

lncRNA ZFPM2-AS1 promotes retinoblastoma progression by targeting microRNA miR-511-3p/paired box protein 6 (PAX6) axis by Wenchang Ni (7907711)

“…We also found that ZFPM2-AS1 targets miR-511-3p to upregulate PAX6 in Y79 and SO-RB50 cells. …”

ATF4 knockdown in the ADRP retinas reduces overall ER stress response (N = 4). by Yogesh Bhootada (408443)

“…The T17M ATF4^+/- retinas were the only group with a significant decrease in peIF2a (P<0.01 as compared to T17M retinas) and increased GADD34 protein levels (<i>P</i><0.05 for all groups). …”

UTX-1 is required for VPA action in <i>C. elegans</i> embryos and in human cells. by Rakel Brendsdal Forthun (121022)

“…<p><b>A</b>) Two <i>UTX</i> wild type cell lines (MV4-11 and NB4) as well as the <i>UTX</i> mutant cell line THP-1 were treated with 1 mM VPA for 48 hours and analyzed for H3K27me3 and H2BK120ac expression. The mean intensity on one representative Western blot was calculated and normalized to beta-actin. …”

Influence of mentalis muscle relaxation on oronasal breathing by Mara Letícia Gobbis (10445129)

“…The mentalis muscle, in its turn, had in the pre- and post-phase, respectively, a mean (standard deviation) of 199.31 (279.77) µV and 114.58 (253.56) µV. …”

Impacts of Human Disturbance on Large Prey Species: Do Behavioral Reactions Translate to Fitness Consequences? by Mathieu Leblond (457233)

“…We hypothesized that human activities and infrastructure cause a decrease in the individual performance of preys because of anthropogenically enhanced predation risk. …”

M-cells are depleted with αRANKL antibody treatment. by Aimee L. Cunningham (650204)

“…<p>BALB/c mice (n = 3 per group) were treated i.p. with 250 μg of either rat Ig (a-b) or αRANKL antibody IK22-5 (c-d) on days 0, 2, 4, and 6. …”

Brazilian Women’s Health after 65 Years of Age by Angela Maggio da Fonseca (4717704)

“…Results The age of the patients on their first clinic visit ranged from65 to 98 years, with a mean age of 68.56 ± 4.47 years; their mean age at the time of natural menopause was 48.76 ± 5.07 years. …”

Igf signaling is required for contribution of<i>gata4:EGFP</i> positive cardiomyocytes to the regenerating area. by Ying Huang (53474)

“…<p><i>gata4:EGFP</i> fish were treated with the Igf1r inhibitor NVP-AEW541 from 2–14 dpa (n = 12) (B, D) and 7–10 dpa (n = 5) (F, H). DMSO was used as a control (14dpa: n = 10; 10 dpa: n = 6) (A, C, E, G). …”

N-acetylcysteine Protects against Apoptosis through Modulation of Group I Metabotropic Glutamate Receptor Activity by Lili Sun (162122)

“…In this study, we investigated the effects of N-acetylcysteine (NAC), a precursor of the antioxidant glutathione, on group I mGlus activation in apoptosis of glial C6 and MN9D cell lines, and a rat model of Parkinson's disease (PD). …”

Regulation of autophagy, mitochondrial dynamics, and cellular bioenergetics by 4-hydroxynonenal in primary neurons by Matthew Dodson (4388749)

“…Finally, inhibition of autophagy initiation using 3-methyladenine (3MA) also results in a significant decrease in mitochondrial function and network length. …”

Heatmap comparing the metabolites extracted from feces of NOD mice at different times point pre- and post-vaccination using GC-MS. by Jacob Cobb (6400340)

“…The statistical significance was calculated using multiple paired <i>t</i> test with Benjamini, Kreiger, and Yekutiele corrected significance level indicated asterisks (*p < 0.05, **p<0.01, ***p<0.005, ****p<0.001). Red asterisks mean a significant increase and black asterisks mean a significant decrease in comparison to the pre-treated group. …”

Evaluation of Pelleting Mealworm (Tenebrio Molitor) Powder with Chokeberry By-product Meal To improve Duck Production and Meat Quality Traits by IH Choi (5838176)

“…<div><p>ABSTRACT This study aimed to evaluate the effects of dietary supplementation pelleted Tenebrio molitor (TM) powder with chokeberry by-product (CBP) meal on duck production and meat quality traits. A total of 180 0-day-old Pekin ducks were allocated randomly between three dietary groups viz., control, Treatment 1, and Treatment 2, with three pens per group and twenty birds per pen, characterized by increasing levels of pelleted TM powder with CBP meal in concentration of 0%, 1.5%, and 3%, respectively, and reared until 42 days of age in a completely randomized design. …”

Supplementary Material for: Evidence of an Acinar Response following Treatment for Exacerbation in Adult Patients with Cystic Fibrosis by Vanderhelst E. (4145263)

“…<b><i>Conclusions:</i></b> In CF patients in whom an improvement in LCI was obtained after treatment for an acute infectious exacerbation, this was paralleled by a decrease in acinar ventilation heterogeneity.…”

Induction of VE-cadherin proteolytic cleavage by <i>P. aeruginosa</i> T2SS. by Guillaume Golovkine (534765)

“…Protein extracts were analyzed by Western blotting with VE-cadherin (BV9) and ß-tubulin antibodies. Data show a decrease in VE-cadherin levels, occurring in infected cells even in absence of the T3 effectors. …”

Regional ventilation distribution. by Günther Zick (20626)

“…No obvious difference between ventilation with 10 ml/kg V_T and inactive interventional lung assist (ILA) (high V_T, no ILA) and ventilation with 5 ml/kg V_T and active ILA (low V_T, ILA) was detected. …”

Geochemistry and zircon U-Pb geochronology of Miocene plutons in the Urumieh-Dokhtar magmatic arc, east Tafresh, Central Iran by Davood Raeisi (6586937)

“…Geochemical signatures of Tafresh plutonic rocks, such as a wide range of Y/Nb (2.7–8.4) and low Zr/Nb (19.5–35.) ratios, Nb/Ta (11.46–18.15), argue for mantle–crust interaction during generation of Tafresh magmas. …”

Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces by Nusret Celik (6033221)

“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10⁵-fold decrease in the attachment of bacteria from urine. …”

Dual-Mode Ultrasensitive Quantification of MicroRNA in Living Cells by Chiroplasmonic Nanopyramids Self-Assembled from Gold and Upconversion Nanoparticles by Si Li (375535)