Basal LAT-diacylglycerol-RasGRP1 Signals in T Cells Maintain TCRα Gene Expression by Evan Markegard (203863)

Table_1_Cardiac and vascular effects of low-dose steroids during the early phase of septic shock: An echocardiographic study.DOCX by François Bagate (9217849)

“…We also observed an increase in LV contractility with improved cardiovascular efficiency (less uncoupling with decreased VAC).…”

Pyrosequencing Reveals Changes in Soil Bacterial Communities after Conversion of Yungas Forests to Agriculture by Marcela S. Montecchia (707075)

Table 1_Dynamic retinal vessel analysis: flickering a light into the brain.docx by Anna Peterfi (16748403)

Image_1_Integrated Transcriptomic and Proteomic Analysis Reveals Up-Regulation of Apoptosis and Small Heat Shock Proteins in Lens of Rats Under Low Temperature.TIF by Jiayue Zhou (10984131)

DataSheet2_Tanreqing Inhibits LPS-Induced Acute Lung Injury In Vivo and In Vitro Through Downregulating STING Signaling Pathway.DOCX by Yu-Qiong He (5568263)

How the size of the to-be-learned material influences the encoding and later retrieval of associative memories: A pupillometric assessment by Péter Pajkossy (335966)

Datasheet1_Fracture rates by medication type in attention-deficit/hyperactive disorder.docx by Jason P. Sidrak (14619125)

Image6_Optogenetic modulation of guanine nucleotide exchange factors of Ras superfamily proteins directly controls cell shape and movement.TIF by Dhiman Sankar Pal (16516836)

Meta data of <i>In vitro</i> and <i>In vivo</i> experiments. by Mohammad Abdullah Taher (18691717)

“…In antidiarrheal testing, 400 mg/kg dose reduced diarrheal episodes by 58.06% compared to control, while in analgesic assay it decreased writhing by 59.18%. …”

Data_Sheet_1_Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers.XLSX by Helen He (345966)

“…Using criteria of fold-change>1.5 and FDR < 0.05, 136 proteins significantly decreased after dupilumab treatment, corresponding to an overall mean improvement of 66.2% in the lesional vs. non-lesional AD proteome. …”

SAP regulates the stability of KIX8 and KIX9. by Na Li (6550)

“…<p><b>(A-B)</b> The proteasome inhibitor MG132 stabilizes KIX8 (<b>A</b>) and KIX9 (<b>B</b>). …”

Table_1_Thalidomide Combined With Azathioprine as Induction and Maintenance Therapy for Azathioprine-Refractory Crohn's Disease Patients.DOCX by Tong Li (206968)

“…During induction, 80.3% (98/122) patients achieved clinical response within a median duration of 6.5 weeks, (interquartile range, 4.3–8.1 weeks). …”

DataSheet1_The Impact of Age on Propofol Requirement for Inducing Loss of Consciousness in Elderly Surgical Patients.pdf by Hua Yang (120668)

“…Compared with group A, the propofol requirement for LOC in Group B, C and D decreased by 14.8, 25.2 and 38.5%, respectively. …”

Fig 1 - by Simone Bach (9339740)

“…The genome harbors 7 protein genes whose mRNA expression levels (schematically shown below the genome, terminal dots indicating the 5’-cap) decrease from the first (NP) to the last (L) mRNA. …”

Modulation of Notch signaling affects axon outgrowth. by Ming Shi (78991)

“…(B–B'') Mis-expression of NICD results in a drastic decrease in the number of commissural axons crossing the midline. …”

Error-threshold exists in fitness landscapes with lethal mutants-0 by Nobuto Takeuchi (24907)

“…The notation and parameters are as follows (unless stated otherwise): The broken line is for = 0.05; the solid line is for = 0.5; the dotted line is for = 1.0; /= 0.99. Points (circles and plus signs) are calculated through the comparison of the first and second greatest eigen values of the model with back mutation [see "How high must lethality be to introduce an error-threshold" and Fig. 4(A) for details]. = 0.05 (the same as in Fig. 3) and = 0.99, unless stated otherwise. …”

Data_Sheet_2_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Animals were monitored for PK following single dose and 17-day repeat dosing, and by clinical observations, hematology, serum biochemistry, coagulation studies and urinalyses. A single trametinib dose (0.025 mg/kg), sulfated as dimethyl sulfoxide which enhanced its absorption, reached mean maximum concentration (C_max) 0.64 ng/mL [18% coefficient of variation (CV)] at a median time to maximum concentration (T_max) of 1.5 h (hr), and mean area under the concentration-time curve (AUC) 16.8 hr^*ng/mL (14%CV), which were similar when given alone or in combination with sapanisertib. …”

Secondary structure in the conserved C-terminal region is responsible for the CAHS filament formation and gelation. by Akihiro Tanaka (342394)

“…By adding TFE (final 20%), CAHS3 protein solutions (4.0 mg/mL) became turbid and transited into a gel-like state. …”

Data_Sheet_1_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Animals were monitored for PK following single dose and 17-day repeat dosing, and by clinical observations, hematology, serum biochemistry, coagulation studies and urinalyses. A single trametinib dose (0.025 mg/kg), sulfated as dimethyl sulfoxide which enhanced its absorption, reached mean maximum concentration (C_max) 0.64 ng/mL [18% coefficient of variation (CV)] at a median time to maximum concentration (T_max) of 1.5 h (hr), and mean area under the concentration-time curve (AUC) 16.8 hr^*ng/mL (14%CV), which were similar when given alone or in combination with sapanisertib. …”