Flow cytometry data - Computationally Engineered CRISPR-SpyCas9 High-Fidelity Variants with Improved Specificity and Reduced Non-specific DNA Damage by Roy Rabinowitz (16908351)

“…<p>EGFP-PEST stable cells were co-transfected with one of the sgRNA plasmids and one of the Cas plasmids, together with a reporter plasmid. Five days post transfection cells were trypsinized, incubated 5 min at 37 °C, and neutralized by 150ul FBS-enriched FACS buffer (PBS; 5% FBS; 25mM HEPES Biological industries (Israel) 03-025; 5mM EDTA, Biological industries (Israel) 01-862). …”

Table_1_Correlation analysis between 18F-fluorodeoxyglucose positron emission tomography and cognitive function in first diagnosed Parkinson’s disease patients.docx by Sun Zhihui (16320159)

“…Further regression analysis showed that for every one-point decrease in the memory score, the glucose metabolism in the right precuneus would decrease by 0.3 (B = 0.30, p = 0.005), the glucose metabolism in the left primary visual cortex would decrease by 0.25 (B = 0.25, p = 0.040), the glucose metabolism in the right lateral occipital cortex would decrease by 0.38 (B = 0.38, p = 0.012), and the glucose metabolism in the left lateral occipital cortex would decrease by 0.32 (B = 0.32, p = 0.045).…”

Table_2_Correlation analysis between 18F-fluorodeoxyglucose positron emission tomography and cognitive function in first diagnosed Parkinson’s disease patients.docx by Sun Zhihui (16320159)

“…Further regression analysis showed that for every one-point decrease in the memory score, the glucose metabolism in the right precuneus would decrease by 0.3 (B = 0.30, p = 0.005), the glucose metabolism in the left primary visual cortex would decrease by 0.25 (B = 0.25, p = 0.040), the glucose metabolism in the right lateral occipital cortex would decrease by 0.38 (B = 0.38, p = 0.012), and the glucose metabolism in the left lateral occipital cortex would decrease by 0.32 (B = 0.32, p = 0.045).…”

Data_Sheet_2_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Animals were monitored for PK following single dose and 17-day repeat dosing, and by clinical observations, hematology, serum biochemistry, coagulation studies and urinalyses. A single trametinib dose (0.025 mg/kg), sulfated as dimethyl sulfoxide which enhanced its absorption, reached mean maximum concentration (C_max) 0.64 ng/mL [18% coefficient of variation (CV)] at a median time to maximum concentration (T_max) of 1.5 h (hr), and mean area under the concentration-time curve (AUC) 16.8 hr^*ng/mL (14%CV), which were similar when given alone or in combination with sapanisertib. …”

Data_Sheet_1_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Animals were monitored for PK following single dose and 17-day repeat dosing, and by clinical observations, hematology, serum biochemistry, coagulation studies and urinalyses. A single trametinib dose (0.025 mg/kg), sulfated as dimethyl sulfoxide which enhanced its absorption, reached mean maximum concentration (C_max) 0.64 ng/mL [18% coefficient of variation (CV)] at a median time to maximum concentration (T_max) of 1.5 h (hr), and mean area under the concentration-time curve (AUC) 16.8 hr^*ng/mL (14%CV), which were similar when given alone or in combination with sapanisertib. …”

DataSheet1_Electrokinetic properties of healthy and β-thalassemia erythrocyte membranes under in vitro exposure to static magnetic field.pdf by Virjinia Doltchinkova (17203663)

“…</p><p>Results: The electrokinetic potential of erythrocytes in norm is increased after SMF intensities due to enhanced negatively exposed charges on the outer surface of the membrane accompanied by an increase in light scattering where changes in cell morphology are observed. Conversely, a decrease in the zeta potential of β-thalassemia erythrocytes upon SMF-treatment was determined because of the reduction in the surface electrical charge of the membranes, where a significant decrease in light scattering at 1.5 T and 2.0 T was recorded. …”

Dris norms for ‘Keitt’ mango in the Brazilian Semiarid Region:Diagnosis and validation by Leonardo Tullio (6015071)

Supplementary Material for: Developing Brain Glucose Transporters, Serotonin, Serotonin Transporter, and Oxytocin Receptor Expression in Response to Early-Life Hypocaloric and Hype... by Ye X. (3610448)

“…In addition, a ∼50% (<i>p</i> = 0.005) decrease in 5-HT and SERT concentrations was displayed in fetal IUGR brains. …”

Laboratory changes inherent to acute kidney injury induced by aminoglycosides in wistar rats by Ana Carolina Queiroz Lima (12817512)

Means of difference in T3 levels according to quintiles of different inflammatory markers between health status and emergency disease status. by Rock Bum Kim (3158643)

Yearly number of individual turtle exports (y-axis) from the United States as reported by Telecky (2001) [17], Reed and Gibbons (2003) [15], and what we reported for purposes of th... by Ivana Mali (515385)

SOIL PHYSICAL ATTRIBUTES BEFORE AND AFTER MANAGEMENT UNDER SOWING FORWARD SPEED by Jorge W. Cortez (5312624)

“…The medium harrowing operation has higher sD and the ideal forward sowing speed range to mitigate this effect would be 5.0 to 7.0 km h−1. Moreover, it also presents a higher amount of macropores in the 0.20–0.30 m layer. …”

ONH and macular OCTA results. by Agne Markeviciute (16426018)

“…</p><p>Practical recommendations</p><p>The observed decrease in peripapillary RNFL thickness of the temporal quadrant, macular RNFL thickness, the decrease of macular VD at the inferior quadrant and decrease in VD of the ONH temporal quadrant in deep capillary plexus could be beneficial for diagnosing glaucoma in high myopia.…”

Clinical characteristics in OAG, M, OAG-M groups. by Agne Markeviciute (16426018)

“…</p><p>Practical recommendations</p><p>The observed decrease in peripapillary RNFL thickness of the temporal quadrant, macular RNFL thickness, the decrease of macular VD at the inferior quadrant and decrease in VD of the ONH temporal quadrant in deep capillary plexus could be beneficial for diagnosing glaucoma in high myopia.…”

S1 Data - by Agne Markeviciute (16426018)

“…</p><p>Practical recommendations</p><p>The observed decrease in peripapillary RNFL thickness of the temporal quadrant, macular RNFL thickness, the decrease of macular VD at the inferior quadrant and decrease in VD of the ONH temporal quadrant in deep capillary plexus could be beneficial for diagnosing glaucoma in high myopia.…”

Demographic characteristics of study subjects. by Agne Markeviciute (16426018)

“…</p><p>Practical recommendations</p><p>The observed decrease in peripapillary RNFL thickness of the temporal quadrant, macular RNFL thickness, the decrease of macular VD at the inferior quadrant and decrease in VD of the ONH temporal quadrant in deep capillary plexus could be beneficial for diagnosing glaucoma in high myopia.…”

Peripapillary RNFL and macular RNFL, GCL+, GCC. by Agne Markeviciute (16426018)

“…</p><p>Practical recommendations</p><p>The observed decrease in peripapillary RNFL thickness of the temporal quadrant, macular RNFL thickness, the decrease of macular VD at the inferior quadrant and decrease in VD of the ONH temporal quadrant in deep capillary plexus could be beneficial for diagnosing glaucoma in high myopia.…”

Table_1_Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in the Conventional Pig as Potential Pediatric Animal Model.DOCX by Joske Millecam (5214191)

“…The present study determined the PK parameters, gastro-intestinal and renal safety of 5 mg/kg BW ibuprofen after single intravenous, single oral and multiple oral administration to each time eight pigs (four males, four females) aging 1, 4, 8 weeks and 6–7 months. …”

<i>In-vitro</i> antioxidant and <i>in-vivo</i> anti-aging with stress resistance on <i>Caenorhabditis elegans</i> of herbaceous peony stamen tea by Jiasong Meng (775090)

Quantification of the damage caused by Meloidogyne enterolobii in okra by Edgard Henrique Costa Silva (5255708)

“…The pathogen showed a parasitism pattern similar to that of M. incognita, causing a significant decrease in morphological and agronomic traits. …”