A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

“…To date, several autotaxin/ENPP2 inhibitors have been reported; however, none were able to completely and continuously inhibit autotaxin/ENPP2 <i>in vivo</i>. In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”

ISA27 induces the stabilisation of p53 protein levels by decreasing the interaction of p53 with MDM2 in GBM cells. by Barbara Costa (447711)

The percent of students who, if a science instructor were to tell a joke about a specific subject, might find the joke funny and might find the joke offensive. by Katelyn M. Cooper (5634851)

Pharmacokinetic analysis of LY5 in mice and normal dogs. by Peter Y. Yu (4281448)

Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ul... by Othmar Moser (789838)

“…</p><p>Results</p><p>BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. …”

IC₅₀ of indole alkaloid against lipase [23]. by Atikarn Janthongkaw (17020498)

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

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Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia by Mary E. Irwin (293687)

“…In two human Ph+ALL cell lines, inhibition of ErbB kinase activity with canertinib resulted in a dose-dependent decrease in the phosphorylation of an ErbB kinase signaling target p70S6-kinase T389 (by 60% in Z119 and 39% in Z181 cells at 3 µM). …”

Cardiac-specific p38γ/δ^act overexpression decreases cardiac glycogen storage and lipid accumulation. by Ayelén M. Santamans (5487941)

Fig 5 - by Elizabeth A. Moore (18083377)

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Chemical Analysis and Antidiabetic Potential of a Decoction from <i>Stevia serrata</i> Roots by Sofía Padilla-Mayne (17027483)

“…Glycoside <b>2</b> (5 and 50 mg/kg) decreased blood glucose levels and the postprandial peak during oral glucose and insulin tolerance tests in STZ-hyperglycemic mice. …”

Table_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.DOCX by Kai Yang (73590)

Image_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.TIF by Kai Yang (73590)

T310A mutation decreases TSP50’s ability to interact with NF-κB:IκBα complex and to promote NF-κB signaling. by Yu-Yin Li (323887)

Decrease in IE expression by HCMV-targeting CRISPR/Cas9 systems. by Janina Gergen (4856863)

Preconditioning anti-VEGF antibody decreased IR-induced pulmonary edema and microvascular hyper-permeability. by Chou-Chin Lan (2938674)

“…The Kf2 was significantly increased in the IR group and decreased in the B5-IR group (5 mg/kg) (p<0.05). There was a significant difference from the * CTRL (<i>p</i><0.05) and ^#IR (<i>p</i><0.05) groups. …”

Preconditioning anti-VEGF antibody decreased total protein concentration and pro-inflammatory cytokines in BALF. by Chou-Chin Lan (2938674)

“…Preconditioning anti-VEGF antibody (5 mg/kg) decreased IR-induced total protein concentration and TNF-α in BALF (both <i>p</i><0.05). …”

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

Flux Growth and Magnetoresistance Behavior of Rare Earth Zintl Phase EuMgSn by Xiaowei Ma (113432)

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