The effect of glibenclamide on channel activity at +20, 0 and -20 mV. by Sajjad Salari (736104)

“…Histogram bars show current amplitudes and P_o of reconstituted channels in absence or presence of glibenclamide. The addition of 50 μM glibenclamide resulted in a decreased current jump amplitude and a reduction in P_o. 100 μM glibenclamide caused a total channel inhibition at +20 and 0 mV (n = 5), but was ineffective at -20 mV. …”

Fli-1 directly activates miR-17-92 promoter and contributes to miR-17 and miR-20a expression in NN10#5 cells. by Samer Kayali (133888)

“…Histogram shows the relative decreases of pri-miRNA-17-92 transcript and mature miRNA levels in treated versus untreated cells (means and standard deviations from 3 independent experiments) with significant (p<0.01) decreases indicated by asteriks. …”

Effects of protein-bound uremic solutes on total glutathione level. by Takeo Edamatsu (4885138)

Measurement of leg length discrepancy (LLD) on a standard anteroposterior bilateral hip radiograph. LLD = 33.68mm – 26.31mm = 7.37mm. by Yang Lu (59885)

Subjects:

Schematic representation of the effects of stepwise bromination of the benzene ring of benzotriazole (Bt), including interdependence of the molecular volume (A) and pK_a (B) of the products with their IC₅₀ for inhibition of protein kinase CK2α: (a) Green arrows follow sequential bromination of the central vicinal C(5)/C(6) atoms, leading to a moderate decrease of pK_a and a large decrease in IC₅₀; (b) Red arrows illustrate the lesser effects of bromination of the peripheral C(4)/C(7) atoms, resulting in a significant decrease of pK_a, with virtually no gain in inhibitory activity; (c) Black lines link products with the same number of bromine atoms, but substantially differing in pK_a and IC₅₀, culminating in the di- and tri-brominated derivatives with inhibitory activities comparable to that of TBBt. by Romualda Wąsik (119538)

Fenretinide decreases levels of PAX3/FOXO1 and its target genes in aRMS cell lines. by David Herrero Martín (286820)

“…D) Fenretinide did not decrease mRNA levels of FOXO1 in aRMS cells. qRT–PCR was carried out after treatment with an IC₅₀ concentration of fenretinide during different time points (24–48–72 hours). …”

Decreased IFNγ production by Ly49H⁺ NK cells in A/J mice. by Nassima Fodil (669326)

Decreased remyelination initiation is observed in Scribble cKO mice following focal demyelination in corpus callosum. by Andrew A. Jarjour (343100)

“…<i>n</i> = 3 mice per genotype. * <i>p</i> < 0.05, ** <i>p</i> < 0.01, *** <i>p</i> < 0.001 versus Scrib WT CL. Scale bars: A,B,D,E: 2 μm. J,K: 50 μm.</p>…”

Detailed meta–analyses in untreated hypothyroid patients compared with controls for each HRV parameters: RR intervals, SDNN, RMSSD, pNN50, TP, LF, HF, LF/HF. by Valentin Brusseau (12769704)

Decrease in the absorbance of PEG₄₀-CONH-(CH₂)₅-CONH-(CH₂)₆-NHCO-MTX with time during dialysis against 1mM HCl. by Itzik Cooper (2873291)

TG6-44 treatment leads to a decrease in NP-positive cells and altered expression patterns of NP in A/X31 infected THP-1 cells. by Juan A. De La Cruz (11154187)

TBEV infection results in decrease of <i>de novo</i> synthesised 45-47S pre-rRNA. by Martin Selinger (3195987)

Cell growth and viability decrease confirmed by growth inhibition in HepG3. by Arlet Hernandez (12289155)

Decreased CCL2 levels protect A20^AEC-KO mice against influenza A infection by Jonathan Maelfait (181048)

Unaltered energy expenditure and decreased physical activity in chow-fed mice with adult-onset hypothalamus-specific Y1Y5 receptor deletion. by Amy D. Nguyen (153830)

Six weeks of voluntary wheel running decreases 5-HT_2C mRNA expression in the medial dorsal striatum. by Benjamin N. Greenwood (295216)

BBS treatment leads to decrease in p53 levels and astrogliosis marker GFAP. by Polina Rabinovich-Toidman (830206)

Akt inhibition by DEBC decreases membrane lipid rafts defined by density floatation. by Fumin Dong (664375)

Decrease in Vitamin D Status in the Greenlandic Adult Population from 1987–2010 by Nina O. Nielsen (490187)

“…In all age-groups it decreased from 1987 to 2005–2010 (32%–58%). Low 25(OH)D3 concentrations (<50 nmol/L) were present in 77% of the 18–29 year old and decreased with age. …”

AtCaM4 decreases GSNOR activity in response to salt stress. by Shuo Zhou (1320660)