Use of Fixed Dose Combination (FDC) Drugs in India: Central Regulatory Approval and Sales of FDCs Containing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Metformin, or Psychotro... by Patricia McGettigan (203640)

“…Data from the CDSCO on approved FDC formulations were compared with sales data from PharmaTrac, a database of national drug sales. We determined the proportions of FDC sales volumes (2011–2012) arising from centrally approved and unapproved formulations and from formulations including drugs banned/restricted internationally. …”

Short-term creatine supplementation changes protein metabolism signaling in hindlimb suspension by G.N. Marzuca-Nassr (7475690)

“…However, creatine supplementation only slightly attenuated the mass loss of both muscles and did not prevent the CSA reduction and muscle strength decrease induced by HS for 5 days.</p></div>…”

Age-Specific Malaria Mortality Rates in the KEMRI/CDC Health and Demographic Surveillance System in Western Kenya, 2003–2010 by Meghna Desai (422151)

“…We collected data from 148,000 persons in a health and demographic surveillance system from 2003–2010. …”

Data_Sheet_1_Identification of the Methanogenesis Inhibition Mechanism Using Comparative Analysis of Mathematical Models.pdf by Magela Odriozola (6677918)

“…We compared models a (M1a to M5a), which consider the inhibition by the concentration of polymer in the bulk liquid, with models b (M1b to M5b) considering the inhibition being caused by the total concentration of polymer in the reactor. …”

Voluntary ethanol consumption during intermittent access. by Andrew K. Haack (546183)

“…Symbols indicate mean ethanol intake ± SEM. In this figure and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092701#pone-0092701-g002" target="_blank">Figures 2</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092701#pone-0092701-g005" target="_blank">5</a>, filled symbols indicate lesioned animals, open symbols indicate sham animals, and asterisks indicate significant differences (p<0.05). …”

Development of the number of required stimuli during training experiments. by Joost le Feber (137427)

“…<p><b>A</b> shows a typical example of an individual ‘learning curve’, as observed in 5 of 10 experiments. …”

AMPK activation by AICAR attenuated the TSH-mediated increase in SREBP-2. by Shudong Liu (733425)

“…<p>(A) TSH decreased AMPK activity. HepG2 cells were synchronized overnight in serum-free EMEM and then treated with AICAR (0.5 mM) or TSH (4 μmol/L) for 24 h. …”

DataSheet_1_Genetically Predicted Circulating Levels of Cytokines and the Risk of Cancer.docx by Jie Song (60883)

“…</p>Results<p>224 genetic variants associated with 27 circulating cytokines achieving genome-wide significance (P<5×10^-8) were used as IVs. After Bonferroni correction, genetically predicted high levels of interleukin-18 (IL-18) were associated with a decreased risk of acute myeloid leukemia (odds ratio (OR) per 1 standard deviation (SD) increase = 0.55, 95% confidence interval (CI):0.43-0.69, P=5.39×10^-7), and circulating levels of IL-17 were associated with altered stomach cancer risk (OR per 1 SD increase = 0.15, 95% CI: 0.07-0.36, P=1.25×10^-5) by IVW. …”

Image_3_Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion.tif by Shan Jiang (121292)

“…The glucose-stimulated insulin secretion level of β-TC6 cells decreased after the upregulation of Cdc42 in MPC5 cells. …”

Image_2_Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion.tif by Shan Jiang (121292)

“…The glucose-stimulated insulin secretion level of β-TC6 cells decreased after the upregulation of Cdc42 in MPC5 cells. …”

Image_1_Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion.tif by Shan Jiang (121292)

“…The glucose-stimulated insulin secretion level of β-TC6 cells decreased after the upregulation of Cdc42 in MPC5 cells. …”

Increased contribution of ultra-processed food products in the Brazilian diet (1987-2009) by Ana Paula Bortoletto Martins (10434155)

DataSheet1_Processing of RNA Containing 8-Oxo-7,8-Dihydroguanosine (8-oxoG) by the Exoribonuclease Xrn-1.PDF by Cheyenne N. Phillips (11702090)

“…To gain a better understanding of the decreased nuclease efficiency, we probed: 1) H-bonding and spatial constraints; 2) anti-syn conformational changes; 3) concentration of divalent cation; and 4) secondary structure. …”

Data_Sheet_1.pdf by Xinyu Wang (341591)

“…The PNP degradation efficiency of a biocathode BES with 0.5 V (Bioc-0.5) reached 99.5 ± 0.8%, which was higher than the degradation efficiency of the BES with 0 V (Bioc-0) (62.4 ± 4.5%) and the OC-BES (59.2 ± 12.5%). …”

Associations between air pollution and cardio-respiratory physiological measures in older adults exercising outdoors by David Stieb (3547763)

“…In the control group, an interquartile range increase in fine particulate matter (PM_2.5) was associated with increases of 1.4% in heart rate (standard error (SE) = 0.7%) and 5.6% (SE = 2.6%) in malondialdehyde, and decreases of 5.6% (SE = 2.5%) to 16.5% (SE = 7.5%) in heart rate variability measures. …”

The application of nano-enrichment in CTC detection and the clinical significance of CTCs in non-small cell lung cancer (NSCLC) treatment by Tengteng Wei (7041785)

“…During six chemotherapy cycles, the average CTC number decreased from 5.8/7.5 ml in cycle #1 to 2.4/7.5 ml in cycle #4 and remained at almost the same level from 4 to 6 cycles. …”

Importance of vegetation variables among bird species with different habitat preferences. by Maria Triviño (190728)

“…For BRT model species number for V1 = 44, V2 = 63 and V3 = 69 whereas for RF model (Mean Decrease Gini measure) the species number for V1 = 21, V2 = 33 and V3 = 31.…”

Supplementary Material for: Microfluidic Assays for Probing Neutrophil-<b><i>Borrelia</i></b> Interactions in Blood During Lyme Disease by Muldur S. (10324079)

“…Preventing complement factor 5 cleavage decreased spontaneous neutrophil motility in Bb-spiked blood. …”

Intrinsic discriminability is determined by the interplay of the dynamic encoding and the free evolution. by Fabiano Baroni (234173)

“…<p>Probability distributions of the difference in the dynamical variables immediately after the last spike of the input train for different values of the average input ISI, which increases along the rows (0.1, 0.2, 0.5, 1, 2, 3, 5). The isolines of the cumulative discriminability as a function of are represented as white lines. …”

Identification of Novel Single Nucleotide Polymorphisms in Inflammatory Genes as Risk Factors Associated with Trachomatous Trichiasis by Berna Atik (270071)

“…TT risk decreased 5 times [odds ratio = 0.2 (95% confidence interval 0.11.–0.33), <em>p</em> = 0.001] with the combination of TNFA (-308A), LTA (252A), VCAM1 (-1594C), SCYA 11 (23T) minor allele, and the combination of TNFA (-308A), IL9 (113M), IL1B (5′UTR-T), and VCAM1 (-1594C). …”