Image_6_Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.JPEG by Hong Meng (82691)

“…The receiver operating characteristic curve analysis showed that the optimal cut-off values of early diastolic SR <0.8 s⁻¹ and indexed RA area > 8.8 cm²/BSA had the best accuracy in identifying patients with RV diastolic dysfunction, with 87% sensitivity and 82% specificity. During a mean follow-up of 25.2 months after pulmonary endarterectomy, the preoperative indexed RA area was shown as an independent risk factor of the decreased 6MWT distance.…”

Image_3_Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.JPEG by Hong Meng (82691)

“…The receiver operating characteristic curve analysis showed that the optimal cut-off values of early diastolic SR <0.8 s⁻¹ and indexed RA area > 8.8 cm²/BSA had the best accuracy in identifying patients with RV diastolic dysfunction, with 87% sensitivity and 82% specificity. During a mean follow-up of 25.2 months after pulmonary endarterectomy, the preoperative indexed RA area was shown as an independent risk factor of the decreased 6MWT distance.…”

Image_6_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Table_1_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.doc by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Image_4_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

PBMC reduces cold hypersensitivity in CFA and CCI but not oxaliplatin pain models. by Wendy M. Knowlton (342969)

“…<b>B</b>) PBMC (10 mg/kg) administered to wildtype mice on day two post-CFA-injection resulted in a significant decrease in scores to 2.5±0.2 (Student's t-test, **p<0.01). …”

Image_3_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Table_2_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.doc by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Image_2_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Image_1_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Datasheet1_Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury.docx by Viviana Delgado-Betancourt (16719402)

“…Consistently, heart rate reduction in Ca_v1.3^+/− or by the f-channel blocker ivabradine was associated with significant decrease in infarct size (−27% and −32%, respectively) in comparison to WT mice.…”

HCMV-Induced Changes in Glycolytic Metabolites by Joshua Munger (66985)

“…Transcriptional data are depicted graphically at the relevant enzymatic step by the following symbols (shown in red): +, increased and −, decreased ≥1.5-fold in HCMV infection versus mock infection and <i>p</i> < 0.05 based on ANOVA analysis; NC, no change, either not significant by ANOVA or effect of HCMV < 1.5-fold. …”

Association between HDACs and pro-inflammatory cytokine gene expressions in obesity by Mehrnoosh Shanaki (3391955)

“…Our findings showed decreased HDAC5 expression in SAT and elevated HDAC4 expression in VAT from the obese group compared with the non-obese group. …”

Figure 4 from Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients by Lauren Polyakov (21672045)

“…<p>Continued use of corticosteroids during anti–PD-L1 therapy correlates with decreased survival in a preclinical model. <b>A,</b> Experimental set-up. …”

Rat splenocytes control intramacrophage <i>Francisella</i> growth that is accompanied by IFN-γ and NO production. by Roberto De Pascalis (187305)

“…<p>BMMΦ from Fischer 344 rats were infected with LVS (Macs), and co-cultured with naïve splenocytes or with immune splenocytes derived from LVS-vaccinated rats. Decreasing numbers of splenocytes were added to a constant number of confluent LVS-infected macrophages, where 1 = 5 x 10⁶, 1/2 = 2.5 x 10⁶, 1/4 = 1.25 x 10⁶, 1/8 = 0.625 x 10⁶, 1/16 = 0.312 x 10⁶, 1/32 = 0.156 x 10⁶ splenocytes. …”

Knockdown of endogenous Miz1 attenuates Hh signaling. by Jiuyi Lu (409742)

“…Stable NIH 3T3 cells infected with either a scrambled shRNA (Scr) or Miz1 shRNA lentiviruses (#3 and #5) were transfected with the Hh-responsive reporter and treated with DMSO or SAG. …”

Battery discharge performance of the µBAR. by Frank B. Myers (440644)

“…Photoamplifier output shows a slight time dependant drift in both cases (7.5 mV/min for wall power and 2.5 mV/min for battery power), but this drift is significantly lower than the signal amplitudes which we see in a typical LAMP assay (∼250 mV, see fig. 6), so we consider it acceptable.…”

EFFECTS OF RENAL DYSFUNCTION ON HEALING OF COLONIC ANASTOMOSIS: EXPERIMENTAL STUDY IN WISTAR RATS by Carlos Eduardo da SILVA (6073667)

“…Decrease of granulation tissue formation (border reepithelialization p=0,0196, angiofibroblast proliferation p=0.0379), mean collagen I (p=0,0009) and collagen III (p=0,016), microvascular density (p=0,0074), cell proliferation nuclear antigen (p<0,0000) and myofibroblasts (p<0,0001). …”

Firing rate propagation through networks of gain-scaling and nongain-scaling neurons. by Julijana Gjorgjieva (255641)

“…Bottom: The network mean firing rates for a range of mean input currents (to layer 1) as a function of layer number, with a clear convergence to the fixed point by layer 5. …”

Data_Sheet_1_Effect of Sublethal Prenatal Endotoxaemia on Murine Placental Transport Systems and Lipid Homeostasis.PDF by Mila W. Reginatto (5297048)

“…At the protein level, breast cancer-related protein (Bcrp) and ABC sub-family G member 1 (Abcg1) levels were decreased in the placental labyrinth zone (Lz) at GD15.5, whereas P-glycoprotein (P-gp) and Bcrp Lz-immunostaining was decreased at GD18.5. …”