γδ T cells have similar TCR threshold but enhanced ERK1/2 phosphorylation comparing to αβ T cells. by Hsin-Yuan Cheng (414160)

“…Results were averaged from 5 mice, and shown in mean ± SEM. Lower: Log scaling of αCD3 concentration against % of maximum response was used to calculate EC₅₀. …”

Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx by Chunyu Yao (13559263)

“…</p>Results and discussion<p>We established three dosage groups (2.5 × 10⁸, 5 × 10⁸, and 1.5 × 10⁹ CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …”

Intense NHS-driven cell-lysis is detected by DNA-content of cell supernatants. by Zoltán Attila Nagy (8163048)

“…In several samples, where cells were treated with above 4% NHS, the C5b-9 MFI values of the C5b-9/PI positive cells topped or even decreased (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008232#ppat.1008232.g009" target="_blank">Fig 9C and 9F</a>) indicating some artefacts. …”

The anchoring mechanism of CaMKII for electrical remodeling in heart failure by rui Feng (11948444)

“…The expressions of CACNA1C (CaV1.2), SCN5A (NaV1.5), and KCNH2 (hERG) were down-regulated, ,and we confirmed that the three genes were closely related to native CaMKⅡ and CaM by protein-protein interaction network analysis. …”

TB-HIV co-infection: spatial and temporal distribution in the largest Brazilian metropolis by Roberta Figueiredo Cavalin (10434051)

“…Incidence rates decreased by 3.6% per year (95%CI -4.4% – -2.7%), declining from 7.0 to 5.3 per 100,000 inhabitants/year. …”

Lactating <i>Igfbp7^−/−</i> glands exhibit accelerated involution. by Sumanta Chatterjee (519822)

“…As shown, lactating KO LD3 glands show elevated Stat3, pSTat3, and Igfbp5, along with decreased Stat5a, IGF-1R, and pAKT; indicating that <i>Igbp7</i>^−/− glands are undergoing involution. …”

RNAi-based DtSER-1 deorphanization. by Mostafa Zamanian (315563)

“…<i>DtSER-1</i> knockdown corresponds to significantly decreased cAMP stimulation (∼32%) in response to 5-HT. …”

Effect of DNA methylation or de-methylation on <i>Pax6</i> gene expression. by Jie Gao (10266)

“…<p><b><i>(A)</i></b> Effect of decreasing DNA methylation on <i>Pax6</i> gene expression in ES cells. …”

DataSheet_1_Palmatine treats urticaria by reducing inflammation and increasing autophagy.docx by Tian Xiao (2601859)

“…Compared with the OVA group, the levels of immune and inflammatory factors were significantly reduced, neutrophil recruitment was alleviated, suggesting a reduced inflammatory response. The autophagy results showed that PAL further increased the expression of LC3, Beclin-1 and p-LKB1, p-AMPK, Atg5, Atg12 and Atg5-Atg12, while P62 and p-p70S6K1 expression decreased. …”

Inhibition of Uterine Sarcoma Cell Growth through Suppression of Endogenous Tyrosine Kinase B Signaling by Kenichi Makino (149077)

“…In <em>in vivo</em> studies in athymic nude mice bearing multidrug-resistant uterine sarcoma cell tumors, we demonstrate suppression of tumor growth by treatment with K252a, but not K252b, as reflected by decreased cell proliferation and increased levels of apoptosis and caspase-3/7 activities without obvious side effects. …”

Image_1_Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling.pdf by Xinghua Qin (6721004)

“…We found that GDL (5 mg/kg, i.p.) attenuated myocardial I/R injury as evidenced by decreased infarct size, release of cardiac injury markers and apoptosis. …”

Table_1_Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling.pdf by Xinghua Qin (6721004)

“…We found that GDL (5 mg/kg, i.p.) attenuated myocardial I/R injury as evidenced by decreased infarct size, release of cardiac injury markers and apoptosis. …”

<b><i>Original data for "High risk of soil available silicon deficiency in bamboo forest: Insights from bamboo afforestation chronosequences in the karst region of southwest China"... by Kangning Yan (22751487)

“…By comparing the variation of five soil ASi proxies, we found that 0.01 M CaCl2 extractable Si (CaCl2-Si, 5.05–26.72 mg kg–1) and water extractable Si (H2O-Si, 4.20–19.89mg kg–1) were the only two proxies that exhibited a consistent declining trend with increasing stand age across all soil layers. …”

Supplementary Material for: Local recurrence in choroidal melanomas following Robotic assisted Radiosurgery (CyberKnife) by Schmelter V. (14069160)

“…Local recurrence occurred after 42.1 months post CyberKnife treatment (mean; range: 5 – 100 months). 14 out of 74 patients (18.9%) died during follow-up. …”

Effects of tiger17 on the MAPKs signal pathway. by Jing Tang (33607)

“…<p>(A) Raw 264.7 cells were treated with the indicated concentrations of tiger17 (2.5, 5, 10, 20 μg/ml) or vehicle; Western blotted for total or phospho-JNK, Erk or P38 was performed. β-Actin was used as the internal control. …”

DataSheet_1_Appropriate pre-transplant strategy for patients with myelodysplastic syndromes receiving allogeneic haematopoietic stem cell transplantation after myeloablative condit... by Hong Wang (13528)

“…However, compared with patients who received HMA, those who received chemotherapy-based therapy had a lower 5-year OS rate (56% vs. 69%, P=0.020) and a slightly higher 5-year NRM rate (28% vs. 18%, P=0.067). …”

Impact of recBCL-XL (ΔTM) microinjection on early embryo development. by Xinyu Liu (34266)

“…In addition, total cell number (TCN) per embryo was significantly increased and cell death index (CDI) was decreased (n = 71 for buffer injection; n = 110 for protein injection). …”

Image 2_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb... by Jiayao Qu (11309880)

“…In fecal samples, a significant reduction in the Ct value of phages was observed following both phases of bacteriophage treatment, with values decreasing from 35.5 to 22.5 and from 32.6 to 22.7, respectively. …”

Image 1_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb... by Jiayao Qu (11309880)

“…In fecal samples, a significant reduction in the Ct value of phages was observed following both phases of bacteriophage treatment, with values decreasing from 35.5 to 22.5 and from 32.6 to 22.7, respectively. …”

Geographic Analysis of Urologist Density and Prostate Cancer Mortality in the United States by Nengliang Yao (760915)

“…</p><p>Findings</p><p>The ordinary least squares (OLS) regression found that, on average, increasing urologist density by 1 urologist per 100,000 people resulted in an expected decrease in prostate cancer mortality of -0.499 deaths per 100,000 men (95% CI -0.709 to -0.289, p-value < 0.001), or a 1.5% decrease. …”