Metabolic and hemodynamic evaluation of two long term sedation protocols in dogs by D. Regalin (8143476)

“…CaO2, CmvO2, DO2 and VO2 decreased in GCM (5%, 16%, 31% and 7% respectively) and GMF (4%, 19%, 26% and 15% respectively). …”

Image_3_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_4_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIFF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_3_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

DataSheet_1_Clinical evaluation of bacterial DNA using an improved droplet digital PCR for spontaneous bacterial peritonitis diagnosis.docx by Hao-Xin Wu (13263747)

“…</p>Results<p>After the removal of free DNA, the bactDNA detected by ddPCR was generally decreased (1.75 vs. 1.5 log copies/µl, P < 0.001). …”

Dynamics of the Ca²⁺ depletion waves. by Mitra Esfandiarei (280455)

“…As the distance from the point of origin increases, the wave velocity decreases asymptotically to zero. <b>C)</b> Average values for <i>R/R₀</i> and [Ca²⁺]_SR at the rim of the depletion wave also decreases as the wave expands over time (ROI = 5, n = 5 independent experiments, mean ± SEM, <i>P</i><0.005).…”

High-resolution SEM analysis of tip links. by Kateri J. Spinelli (293686)

“…(e, f) Bundles treated with 5 mM EGTA for 5 min showed a marked decrease in bundle Fluo-4 fluorescence and a significant reduction in the number of tip links (g, h). …”

Diffusive dynamics of white player’s advantage. by Haroldo V. Ribeiro (277883)

The <i>I</i>_K1/Kir2.1 channel agonist zacopride prevents and cures acute ischemic arrhythmias in the rat by Xu-Wen Zhai (4033601)

“…However, clinical anti-arrhythmic agents that primarily act on RMP by enhancing the <i>I</i>_K1 channel are not currently available. We hypothesized that zacopride, a selective and moderate agonist of the <i>I</i>_K1/Kir2.1 channels, prevents and cures acute ischemic arrhythmias. …”

<i>Self-stimulation driven by VTA dopamine neurons is attenuated by intra-NAc D1 and D2 receptor antagonists.</i> by Elizabeth E. Steinberg (551612)

“…Note that responding from saline sessions remains close to the baseline value while responding after drug treatment steadily decreases. Data represent the mean of all rats (n = 5), SEM not shown. …”

Plasmin mediated cleavage of C3 is enhanced by Sbi and Efb. by Tina K. Koch (303277)

“…<p>(A) In the presence of Sbi and Efb (lane 1 and 2) the C3 α-chain decreased and C3 cleavage products (indicated by arrows) appeared. …”

OVA-induced airway inflammation is attenuated by oral administration of SH-2251. by Junpei Suzuki (403143)

“…<p><b>(A)</b>, Decreased infiltration of eosinophils in the BAL fluid of asthmatic SH-2251-administered mice. …”

HS/heparin GAGs inhibit the development of NV in OIR. by Koji M. Nishiguchi (147632)

“…<p>(A) Breakdown of HS GAGs by heparinase III (HIII). …”

Dose response inhibition of IP6K1 by TNP in the presence of different concentrations of ATP and IP6. by Michael Wormald (4631122)

“…(B) IC₅₀ values decreased slightly from 24±1.5μM to 9.5±1.5μM as IP6 concentrations were increased from 50μM to 400μM. …”

Quantitative disruption of ER-PM contacts in Δ-s-tether cells. by Evan Quon (5244278)

“…It interacts with the PM via its C-terminal PI(4,5)P₂-binding polybasic region (++) [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2003864#pbio.2003864.ref034" target="_blank">34</a>]. …”

Properties of the optimal force selection model. by Nicolas Borderies (9510718)

“…<b>C2</b>: increase of K_e (sensitivity to effort) leads to decrease of optimal value and decrease of optimal force with a collapse to zero-force when the optimal value becomes negative. …”