Influence of the methanol supply on DNase1 expression. by Jan-Ole Krischek (21213122)

“…<p>(A) Raising MeOH above 0.5% (v/v) in the expression medium increases preαMF-mDNase1 production with an optimum at 5% MeOH and 24 °C (p =  0.0059) and even more at 2.5% and 28 °C (p =  0.0441) as determined by HCA of SN. …”

Relation between Intramolecular NH···S Hydrogen Bonds and Coordination Number in Mercury(II) Complexes with Carbamoylbenzenethiol Derivatives by Masahiro Kato (55602)

“…Conversely, the ¹⁹⁹Hg NMR spectra in <b>5</b> show a high-field shift with a decrease in the flow of electrons to mercury(II) from the sulfur atom due to the intramolecular NH···S hydrogen bond.…”

Relation between Intramolecular NH···S Hydrogen Bonds and Coordination Number in Mercury(II) Complexes with Carbamoylbenzenethiol Derivatives by Masahiro Kato (55602)

“…Conversely, the ¹⁹⁹Hg NMR spectra in <b>5</b> show a high-field shift with a decrease in the flow of electrons to mercury(II) from the sulfur atom due to the intramolecular NH···S hydrogen bond.…”

Modulation of gamma oscillations by speed in CA1 is rapid. by Caleb Kemere (452950)

“…Periods of decreasing speed are marked by an increase in slow gamma power (blue bars) and a concomitant decrease in fast gamma power (red bars). …”

Cell stress, the UPR and <i>headcase</i>. by Panagiotis Giannios (10113763)

“…Synchronous overexpression of a <i>UAS-hdc</i> with an RNAi against Xbp1 <b>(F)</b> and PEK <b>(J)</b> results in the decrease in the observed apoptotic death, compared to the UPR disruption after knockdown of its mediators (<i>Xbp1</i> <b>(D)</b> and <i>PERK</i> <b>(H)</b>) alone. …”

Image1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Table1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.docx by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Image3_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Image2_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Long-term use of cover crops and no-till shift soil microbial community life strategies in agricultural soil by Radomir Schmidt (1956940)

“…In long-term experimental plots at the West Side Research and Extension Center in California’s Central Valley, we characterized soil microbial communities in the presence or absence of physical disturbance due to tillage, in the presence or absence of cover crops, and at three depths: 0–5, 5–15 and 15–30 cm. …”

Over-expression of NF-Y or USF increases <i>Miwi</i>-luciferase activity. by Yu Hou (164094)

“…All transfection experiments were repeated at least three times and the data are shown as the fold increase or decrease over the luciferase activity of pGL3-5M4. …”

Dose effect on response frequencies and latencies. by Dominique Martinez (229854)

“…The grey bar indicates the stimulus (pheromone blend of 200 ms at 5 different doses, from 0.001 to 10 ng). The dotted line represents the baseline activity (mean frequency). …”

CYP dosing conditions differentially altered PLCβ2 expression in circumvallate taste buds. by Eugene R. Delay (405477)

“…<p>(A). PLCβ2+ cells (magenta) in taste buds after saline injections (Saline, top row), a single injection of 75 mg/kg CYP (1CYP, middle row), or five injections of 15 mg/kg CYP (5CYP, bottom row) at 2 days (left column), 6 days (middle column), and 10 days (right column) post injection. …”

Table_1_Validation and analysis of expression, prognosis and immune infiltration of WNT gene family in non-small cell lung cancer.docx by Jianglin Wang (1569508)

“…Compared with that of normal tissues, WNT2/2B/3A/4/7A/9A/9B/11 expressions decreased, while WNT3/5B/6/7B/8B/10A/10B/16 expressions increased in lung adenocarcinoma (LUAD); WNT2/3A/7A/11 expressions were lessened, while WNT2B/3/5A/5B/6/7B/10A/10B/16 expressions were enhanced in squamous cell lung cancer (LUSC). …”

McDonald versus Shirodkar cervical cerclage for the prevention of preterm birth: impact of body mass index by Reinaldo Figueroa (5432579)

“…</p> <p><b>Results:</b> Of 95 women, 47 (49.5%) received a Shirodkar, and 48 (50.5%) a McDonald cerclage. 16 women (16.8%) were categorized as normal weight, 35 (36.8%) as overweight, and 44 (46.3%) as obese. …”

Table_2_Validation and analysis of expression, prognosis and immune infiltration of WNT gene family in non-small cell lung cancer.docx by Jianglin Wang (1569508)

“…Compared with that of normal tissues, WNT2/2B/3A/4/7A/9A/9B/11 expressions decreased, while WNT3/5B/6/7B/8B/10A/10B/16 expressions increased in lung adenocarcinoma (LUAD); WNT2/3A/7A/11 expressions were lessened, while WNT2B/3/5A/5B/6/7B/10A/10B/16 expressions were enhanced in squamous cell lung cancer (LUSC). …”

NHERF1 protein levels are reduced by both high and low-risk E6 proteins. by Camille M. Drews (4721175)

“…Titrations of the indicated E6 proteins were co-transfected with FLAG_E6AP_WT (1 ug), HA_GFP (0.02 ug), and either HA_NHERF1 (0.5 ug) or p53 (0.5 ug) in murine 8B9 cells. With increased E6 expression, NHERF1 decreased for each E6 protein parallel with p53. …”

Data_Sheet_1_Identification of Valerate as Carrying Capacity Modulator by Analyzing Lactiplantibacillus plantarum Colonization of Colonic Microbiota in vitro.docx by Julia Isenring (3533741)

“…However, extensive knowledge about host-independent microbe-microbe interactions is lacking. Here, we investigated such colonization process using a derivative of the model probiotic Lactiplantibacillus plantarum WCFS1 into continuously cultivated gut microbiota in the intestinal PolyFermS fermentation model inoculated with five independently immobilized human adult fecal microbiota. …”

Regulation of Cyclin E by transcription factors of the naïve pluripotency network in mouse embryonic stem cells by Fabrice Gonnot (7323194)

“…We observed that mESCs express a low level of miR-15a and that transfection of a miR-15a mimic decreases <i>Cyclin E</i> mRNA level. …”

S1 Dataset - by Chenyi Xia (11283023)

“…Our results showed elevated H₂O₂ levels and monoamine oxidase (MAO) activity, and conversely, a decrease in the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the hippocampus of AD rats. …”