Video5_Magnetospheric responses to solar wind Pc5 density fluctuations: Results from 2D hybrid Vlasov simulation.MP4 by Hongyang Zhou (2352637)

“…With the new time-varying boundary setup, we introduce a monochromatic Pc5 range periodic density variation in the solar wind. …”

DAS and Y27632 down-regulated the mRNA and protein expression of CK8-RhoA/ROCK1 pathway and up-regulated TJs expression in intestines of infected mice. by Wen Wen Zheng (17721404)

Parkinson’s and age-matched control results. by Adam M. Roth (19845864)

Reducing SIRT1 activity increases, and increasing SIRT1 expression decreases, mitochondrial enzymes in C₂C₁₂ myotubes and rat skeletal muscle. by Kazuhiko Higashida (351645)

“…Values are means ± SE for 6–10 experiments per group. <i>p</i><0.5 versus control. (B) Suppression of SIRT1 activity by expression of dominant-negative SIRT1 H355A in rat triceps muscle by electroporation resulted in increases in mitochondrial proteins. …”

Peroxidase immunohistochemistry illustrating the changes in distribution pattern of SSTR1-5 in striatum of R6/2 and SSTR1/5^−/− mice. by Padmesh S. Rajput (206935)

“…<p>SSTR1(53 kDa) like immunoreactivity increased in striatum of R6/2 mice and abolished completely in SSTR1/5^−/− mice (<b>a</b>). SSTR2 (57 kDa) like immunoreactivity was increased in R6/2 and SSTR1/5^−/− mice (<b>b</b>). …”

Loss of FAM83A expression induces apoptosis and inhibits PI3K/Akt signaling. by Courtney A. Bartel (3993173)

“…(C) Live cells were stained with an antibody detecting the early apoptosis marker Annexin V. Knockdown of FAM83A resulted in elevated expression of Annexin V. …”

SRSF5 expression in primary ex-vivo erythroid precursors. by Osman Breig (388133)

“…After 2 days of maturation, these cells display a cell size decrease (low FSC), and cell surface phenotype changes, including Kit decrease and higher levels of CD71 and Ter119.B. …”

HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer by Yan Gao (93649)

“…This results in decreased ATG5 levels, inhibiting autophagy and thus reducing 5-FU resistance in colorectal cancer cells both <i>in vitro</i> and <i>in vivo</i>. …”

Role of the −5 bp in <i>sodB</i> regulation. by Beth M. Carpenter (373215)

“…<p>WT G27, WT 26695, and the “−5 bp swap” strain were grown as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005369#s2" target="_blank">Materials and Methods</a>, and RNA was isolated under iron replete and iron-depletion shock conditions. …”

<i>In vitro</i> characterization of key marker proteins AQP5, ANO1, α-SMA, and CEACAM5 in cultures of the SG by immunofluorescence staining. by Patricia Klaka (4347595)

“…<p>(A) Stained secretory coil (sc) and duct (du) sections of native human sweat glands were analyzed in axillary skin tissue (a,d,g,j) compared to <i>in situ</i> glands (dashed lines) with outgrowing cells in 2D cultures (b,e,h,k) and 3D models (c,f,i,l). …”

Table_5_Alteration of mRNA 5-Methylcytosine Modification in Neurons After OGD/R and Potential Roles in Cell Stress Response and Apoptosis.XLSX by Huan Jian (10077037)

“…<p>Epigenetic modifications play an important role in central nervous system disorders. As a widespread posttranscriptional RNA modification, the role of the m⁵C modification in cerebral ischemia-reperfusion injury (IRI) remains poorly defined. …”

Experimental design. by Xueyan Lin (448667)

“…The MHE model rats were given subcutaneous injections of 3 mL/kg of CCl4 solution (a mixture of CCl₄ and olive oil at a ratio of 1:1 v/v) twice a week and were fed 5% alcohol in drinking water for 9 consecutive weeks. …”

Effects of AP-5 application on EPSCs in control and hyperglycemic mice. by Eva C. Bach (709723)

“…Arrows point to expanded sections of traces indicated in <b>A</b> and <b>B</b>. <b>C.</b> Mean percent decrease in sEPSC frequency following application of AP-5 in control (n = 5) and hyperglycemic (n = 6) mice (asterisk indicates significant difference from control mice; p<0.05, Mann-Whitney U test). …”

Overexpression of DJ-1 full length prior to oxidative stress leads to decreased levels of H₂O₂-induced ROS generation by RPE cells. by Karen G. Shadrach (429721)

ASO-miR-129-5p down-regulates miR-129-5p and reduces proliferation and migration of Hep-2 cells by MingHua Li (3522803)

“…<p>. (A) miR-129-5p expression was significantly decreased after ASO-miR-129-5p transfection compared to GFP transfection (control) or untreated Hep-2 cells (Hep-2 cell) measured by real-time RT-PCR. (* <i>P</i><0.05). …”

Image_5_5-Methylcytosine Related LncRNAs Reveal Immune Characteristics, Predict Prognosis and Oncology Treatment Outcome in Lower-Grade Gliomas.tif by Jiheng Zhang (11953919)

“…Consequently, we identified four lncRNAs, including LINC00265, CIRBP-AS1, GDNF-AS1, and ZBTB20-AS4, and established a novel m5C-related lncRNAs signature (m5CrLS) that was effective in predicting prognosis. …”

Pathway analysis of genes differentially expressed upon RBM10KD in GLC20 cells. by Julie J. Loiselle (4183750)

“…(B) MSigDB Hallmark gene sets enriched at a false discovery rate of below 5% upon RBM10KD in GLC20 cells. …”

Example of cross-section of mouse skin. by Igor Sokolov (361571)

HbA1c Reduction in Dulaglutide-Treated Patients Irrespective of Duration of Diabetes, Microvascular Disease, and BMI: A Post Hoc Analysis From the REWIND Trial by Anita Y.M. Kwan (11868016)

“…</p> <p><b>Conclusions:</b> Dulaglutide 1.5 mg treatment was statistically associated with a long-lasting decrease in HbA1c over 72 months, irrespective of baseline duration of diabetes, microvascular disease, and BMI.…”

Change in the cell size. by Igor Sokolov (361571)