Heat-killed <i>A</i>. <i>persici</i> shortens lifespan and increases the host defence but does not enhance paraquat resistance. by Taro Onuma (15195377)

Mechanistic Insights on the Inhibition of C5 DNA Methyltransferases by Zebularine by Christine Champion (243238)

“…First, we observe an increase in the DNA binding when zebularine is incorporated into the DNA, compared to deoxycytidine and 5-fluorodeoxycytidine, together with a strong decrease in the dissociation rate. …”

Replacement of intra- and extracellular chloride for D-gluconate eliminated statistically significant decreases in GLT-1 stoichiometric current and the current/flux ratio in 100–30... by Anatoli Y. Kabakov (729047)

UCH-L5 regulates inflammasome activity in chicken macrophages. by Evangel Kummari (719636)

“…<p><b>(A-B). UCH-L5 overexpression leads to reduced cell viability in infected as well as uninfected HD11 macrophages, which depends on its catalytic activity.…”

CD43^-/- septic mice exhibit decreased frequencies of apoptotic CD4⁺ and CD8⁺ naïve T cells as compared to WT septic mice. by Katherine T. Fay (2576998)

“…B) CD43^-/- septic mice exhibited a decreased frequency of apoptotic naïve CD4⁺ T cells, defined as 7-AAD⁺ Annexin V⁺ CD44^LO CD62L^HI CD4⁺ cells, compared to WT septic mice (11.8±1.6 vs 18.8±1.3, p = 0.002. …”

Results of the fitting process of the basic epidemiological model (i.e., without vaccinations). by Matthias Horn (78815)

CBD (30 mg/kg, n = 7–9 animals/group) and HU-101 (10 mg/kg, n = 9–10 animals/group) decreased the number of buried marbles in the MBT. by Aviva Breuer (3153021)

Inflammation Regulates TMPRSS6 Expression via STAT5 by Delphine Meynard (87311)

“…The downregulation of Tmprss6 by inflammation in mice is not dependent on the Bmp-Smad pathway but occurs through a decrease in Stat5 phosphorylation. Moreover, Stat5 positively regulates Tmprss6 expression directly by binding to a Stat5 element located on the Tmprss6 promoter. …”

Supplementary Material for: Waning of SARS-CoV-2 Vaccine-Induced Immune Response over 6 Months in Peritoneal Dialysis Patients and the Role of a Booster Dose in Maintaining Seropos... by Murt A. (9984845)

“…Humoral immune responses were measured by a commercial test that detects antibodies toward the receptor-binding domain of the spike protein of SARS-CoV-2. …”

Image5_Spinel harzburgite–derived silicate melts forming sulfide-bearing orthopyroxenite in the lithosphere. Part 2: Sulfide compositions and their chalcophile and highly siderophi... by A. Bénard (13030182)

S1 data_Hazen Main and Blister 2017 absolute diatom counts from Contrasting the ecological effects of decreasing ice cover versus accelerated glacial melt on the High Arctic's larg... by Neal Michelutti (688828)

“…Increased glacial meltwater can alter the ecological functioning of recipient aquatic ecosystems via changes to nutrient budgets, turbidity and thermal regimes. Here, we examine a rare set of five high-resolution sediment cores collected in Lake Hazen between 1990 and 2017 CE to investigate the influence of increased glacial meltwater versus alterations to lake ice phenology on ecological change. …”

Transitioning of people with T1D from Multiple Daily Injections (MDI) and Self-Monitoring of Blood Glucose (BGM) directly to MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system... by Bartłomiej Matejko (13180606)

“…</p> <p>Results: 41 participants were recruited and randomized to either the AHCL (20) or the MDI+BGM (21) group. 37 participants (age 40.3±8.0 years; duration of diabetes 17.3 ± 12.1 years; BMI 25.1±3.1 kg/m2; HbA1c 7.2% ± 1.0) completed the study. Time spent in target (TIR) increased from 69.3±12.3% at baseline to 85.0±6.3% at 3 months in the AHCL group, while remaining unchanged in the control group: treatment effect 21.5% [95% CI 15.7, 27.3%]; p < 0.001. …”

UCH-L5 regulates inflammasome activity in human macrophages. by Evangel Kummari (719636)

“…<p><b>(A). Exposure of THP-1 macrophages to b-AP15 inhibitor leads to decrease in IL-1β upon inflammasome activation.…”

Adjusted Hazard Ratios (HRs) for death risks according to handgrip strength. by Kaihong Xie (13955203)

Data_Sheet_1_rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels.docx by Munal B. Kandel (18526539)

“…This study tested the hypothesis that novel JDNI8 replication-defective herpes simplex-1 viral vectors (rdHSV) carrying a CA8 transgene (vHCA8) reduce primary afferent neuronal excitability. …”

Table_1_Decreased circulating dipeptidyl peptidase-4 activity after short-term intensive insulin therapy predicts clinical outcomes in patients with newly diagnosed type 2 diabetes... by Jie Chen (5892)

“…After three months post-SIIT, DPP-4 activity remained stable in the remission group (39.63 ± 8.53 nmol/L) but increased in the non-remission group (42.34 ± 6.64 nmol/L). This resulted in a more pronounced decrease in DPP-4 activity from baseline in the remission group (-3.39 ± 8.90 vs. -1.10 ± 8.95, P = 0.035). …”

Stacked bar plots of predicted absolute IPD cases per year from 2006 to 2031 in Germany for three different age groups (<2y, 16-59y, ≥60y). by Matthias Horn (78815)

Prediction of absolute IPD cases per year from 2006 to 2031 in Germany for three different vaccine serotype groups (PCV13, PCV15, PCV20; rows) and three age groups (<2y, 16-59y, ≥6... by Matthias Horn (78815)

Aβ₄₂–induced increase in phosphorylated tau is attenuated by PADK. by Karen L. G. Farizatto (4348537)

Expression of grapevine expansins in the V. vinifera cv Corvina atlas. by Silvia Dal Santo (268493)