Diaporaustalides A–L, Austalide Meroterpenoids from a Plant Endophytic <i>Diaporthe</i> sp. by Jin-Ling Chang (8752320)

“…Compounds <b>2</b> and <b>5</b> decreased the secretion of IL-6 in LPS-induced B cells in a dose-dependent manner.…”

Diaporaustalides A–L, Austalide Meroterpenoids from a Plant Endophytic <i>Diaporthe</i> sp. by Jin-Ling Chang (8752320)

“…Compounds <b>2</b> and <b>5</b> decreased the secretion of IL-6 in LPS-induced B cells in a dose-dependent manner.…”

Diaporaustalides A–L, Austalide Meroterpenoids from a Plant Endophytic <i>Diaporthe</i> sp. by Jin-Ling Chang (8752320)

“…Compounds <b>2</b> and <b>5</b> decreased the secretion of IL-6 in LPS-induced B cells in a dose-dependent manner.…”

<i>L. monocytogenes</i> causes LLO-mediated downregulation of CD117 but not FcεRI on BMMC and decreases chemotaxis. by Catherine E. Jobbings (382681)

Therapeutic administration of mMSCs failed to decrease pulmonary inflammation or modify BAL inflammatory cell counts in experimental severe influenza. by Ilyse Darwish (446378)

M1-37T protein is degraded in a lysosome-independent manner, and its ubiquitination is not through K48 linkage. by Chenxi Wang (284364)

Subjects:

M1 protein harboring T37 is susceptible to ubiquitination at K187. by Chenxi Wang (284364)

Subjects:

T37A mutation protects M1 protein of BJ/3/99 virus from degradation directed by PKG and increases the viral replication. by Chenxi Wang (284364)

Subjects:

Stability of the H9N2 M1 protein of BJ/3/99 virus is increased by the T37A mutation. by Chenxi Wang (284364)

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The stability of H9N2 M1 protein is increased by the replacement of T37 with A37. by Chenxi Wang (284364)

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CXCL10 production is enhanced in the setting of HIV and HBV co-infection in vitro and decreased with the addition of antiretroviral agents efavirenz or raltegravir. by Kasha P. Singh (9354307)

APB5, but not APA5, decreases apoptosis in alveolar epithelial cells in lungs of BLM-treated mice. by Masami Kishi (6167105)

“…The administration of APA5 did not change the number of TUNEL-positive cells from that in BLM-treated mice, whereas that of APB5 significantly decreased them. …”

HC-070 decreases anxiety after CCK-4 treatment in an EPM. by Stefan Just (4811358)

Over-expression of DN VPS4 in HEK293T cells leads to increased extracellular α-synuclein and parallel decrease in lysosome. by Takafumi Hasegawa (18204)

“…As shown in the blot, marked increase of extracellular αSYN monomer and multimers (<i>white arrow</i>) concomitant with slightly decreased lysosomal αSYN-immunopositive smear (<i>open triangle</i>) were observed by over-expression of DN VPS4A. …”

TrpA1 activation fails to enhance the increase in synaptic bouton number and axon branching conferred by <i>atl</i> loss. by Saurabh Srivastav (9585817)

<i>Cdkl5</i> -/Y mice show an increased freezing time and a decreased distance traveled during the pretone period in the altered context. by Kosuke Okuda (5150393)

“…<i>Cdkl5</i> -/Y mice show a significantly decreased distance traveled in response to the first footshock (p = 0.0158) compared with control mice. …”

a-c: Proximal tibia (PT) EPO receptor (EPO-R) decreases in uremic rats, as shown by Western blot (Fig. 5a) and immunohistochemistry (Fig. 5b). by Daniel Landau (440830)

“…Animals received a single bolus of IV rhEPO (25 U/kg) or saline, 5 minutes prior to sacrifice. …”

5-HT supplementation inhibits mitophagy. by Li Gao (131516)

Pharmacological inhibition of EGFR decreases early fungal burden and reduces the inflammatory response. by Marc Swidergall (185453)

Mitochondrial damage is a key event in the mechanism of oncosis in skeletal muscle cells. by Chengcheng Li (2591632)