Gramine Derivatives Targeting Ca²⁺ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases by Rocío Lajarín-Cuesta (1530580)

“…Hence, we propose this multitarget approach as a new and promising strategy for the treatment of neurodegenerative diseases.…”

Data_Sheet_1_Risk of psychological distress by decrease in economic activity, gender, and age due to COVID-19: A multinational study.PDF by Minji Kim (1722313)

“…Moreover, countries with lower HDI showed a higher prevalence of decrease in economic activity, especially at lower education levels.…”

Loss of neuronal Pol III transcription does not affect lifespan, and gut 5S rRNA or brain <i>dMaf1</i> levels do not change during aging, with decreased Pol III subunits levels wit... by Bowen Xu (5903801)

Quantitative PCR of RNA from lung cells demonstrates a decrease in negative regulators of Th1 immunity in Mtb challenged vaccinated rats. by Amit Singhal (193686)

Weighted odds ratios reflecting the impact of a genetically determined 10 mg/dL decrease in LDL-C on safety and efficacy endpoints. by Aeron M. Small (9617751)

“…<p>Odds ratio and 95% confidence interval is displayed for the effect of a genetically determined 10 mg/dL decrease in LDL-C on safety and efficacy endpoints for White individuals, Black individuals, Hispanic individuals, and inverse variance weighted meta-analysis of White, Black, and Hispanic populations (IVWMA). …”

<i>Entamoeba histolytica</i> promotes the degradation of the cullin-1/5 from BMDM in a time and dose-dependent manner. by Attinder Chadha (11414273)

Subjects:

Administration of BL-7010 (Polymers A and B) at a gluten: BL-7010 ratio of 1∶3 decreased gluten-associated histological pathology in the small intestine of sensitized mice. by Justin L. McCarville (432593)

Dvl2-Dependent Activation of Daam1 and RhoA Regulates Wnt5a-Induced Breast Cancer Cell Migration by Yichao Zhu (3666262)

“…Dominant negative Dvl2 mutants or Dvl2 siRNA significantly decreased Wnt5a-induced Daam1/RhoA activation and cell migration. …”

Agonist of A3 receptors (IB-MECA) enhanced elastase release of fMLP-stimulated PMN, while A1 receptor agonist (CPA) decreased PMN degranulation by admin admin (96369)

Appendix A. Table A1. Distribution of the decreased susceptibility-to-DDAC phenotype in the panel for genomic characterization (n = 41), according to the year of strain isolation,... by Marine Pottier (14099133)

Berberine inhibits 4-AP-induced glutamate release from rat cerebrocortical nerve terminals; this effect is due to a decrease in vesicular exocytosis. by Tzu-Yu Lin (423761)

“…<p>Glutamate release (+Ca²⁺; A) and Ca²⁺-independent glutamate release (-Ca²⁺; C) was measured under control conditions or in the presence of 10 µM berberine added 10 min prior to the addition of 4-AP. …”

FK866 treatment causes a time dependent decrease in cellular NAD⁺/NADH and NADP⁺/NADPH content. by Gerda Venter (559404)

Elderly population have a decreased aneurysmal subarachnoid hemorrhage incidence rate than Middle aged population: a descriptive analysis of 8,144 cases in mainland China by Yì Xiáng J. Wáng (4774266)

SH-SY5Y cells are responsive to acute insulin stimulation and altered insulin signaling impacts choline uptake by CHT. by Katherine J. Fishwick (768451)

Table_1_Decrease in Admissions and Change in the Diagnostic Landscape in a Newborn Care Unit in Northern Ghana During the COVID-19 Pandemic.DOC by Alhassan Abdul-Mumin (5986151)

“…</p><p>Conclusion: We observed a marked decrease in admissions and change in the diagnosis landscape and related mortality during the pandemic. …”

<i>PGRP-LC</i> knockdown in gut mitigates the decrease in lifespan caused by heat-killed <i>A</i>. <i>persici</i>. by Taro Onuma (15195377)

Lumen diameter (77.9±5.6 vs 120.6±5.5 µm at 75 mmHg, <i>p</i><0.001), external diameter (110.4±6.4 vs 153.1±5.2 µm at 75 mmHg, <i>p</i><0.001) and media cross-sectional area (4860.4±464.7 vs 6972.4±272.1 µm² at 75 mmHg, <i>p</i><0.001) were increased in 16 wk-old db/db MRAs while wall:lumen ratio (21.3±1.2 vs 13.7±0.8 at 75 mmHg, <i>p</i><0.01) was decreased when compared to Db/db mice under physiological pressures of 50, 75 and 100 mmHg: a.... by Flavia M. Souza-Smith (346803)

Image_5_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOTCH1, MKI67, OCT4, and MUC5AC via HIF1A Upregulation in Human Bronchial Epithelial Cells.TIF by Yung-Yu Yang (9343376)

“…Inhibition of HIF1A or NKX2-1 expression by siRNA transfection respectively decreased BMP4/NOTCH1/MKI67/OCT4/MUC5AC and NOTCH3/HEY1/CC10/FOXJ1 expression in the HBE cells cultured under intermittent H/R to the same levels under normoxia. …”

RavZ_LLO decreases the association of polyubiquitinated species with the LCV harboring <i>L</i>. <i>longbeachae</i>. by Yunjia Shi (14593468)

A-C: Postoperative transverse plane computed tomography images at the level of the cervical articular process joints obtained 3.4 years after cervical interbody fusion at C5-6 (Hor... by Devon England (21262225)