Data Sheet 1_Understanding the long-term interplay of SARS-CoV-2 immune and inflammatory responses with proteases in COVID-19 recovery: a longitudinal study.pdf by Natalia Ćwilichowska-Puślecka (21515129)

“…</p>Results<p>Our comprehensive approach revealed significant changes in the immune system over time, highlighting the role of specific immune cells and proteases in the recovery process. Key findings include a decreasing deregulatory effect on immune responses exerted by subsequent SARS-CoV-2 variants Alpha, Delta, and Omicron.…”

Measurements of buffer viscosity as a function of shear rate in the absence and presence of polyethylene glycol (PEG). by Fatema Tuz Zohra (11378812)

Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome by Magnus Mathias Dötsch (806772)

“…<div><p>Inter-α-trypsin inhibitor heavy chain 5 (ITIH5) is supposed to be involved in extracellular matrix stability and thus may play a key role in the inhibition of tumor progression. …”

Two-parameter bifurcation diagrams of the DA neuron and the HH neuron in <i>v</i>_nh/<i>v</i>_hh/<i>v</i>_mh and <i>I</i>_app planes. by Andrey Dovzhenok (311885)

“…E) Hysteresis is removed in the HH neuron with an increase of <i>v</i>_hh. Parameters are from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042811#pone-0042811-g004" target="_blank">Figure 4D</a>. …”

Age-standardized rates of PUD in 204 countries globally by SDI in 2021. by Wende Hao (10315597)

Age-standardized rates of PUD globally and for 21 GBD regions by SDI, 1990–2021. by Wende Hao (10315597)

Sensitivity analysis. by Ying Zhao (16546)

Trends in the all-age numbers and age-standardized incidence, prevalence, mortality and DALYs rates of PUD by sex from 1990 to 2021. by Wende Hao (10315597)

Joinpoint regression analysis of the sex-specific ASRs for PUD globally from 1990 to 2021. by Wende Hao (10315597)

Age-specific numbers and rates of PUD globally in 2021 for both sexes. by Wende Hao (10315597)

Data_Sheet_5_Agroclimatic Metrics for the Main Stone Fruit Producing Areas in Spain in Current and Future Climate Change Scenarios: Implications From an Adaptive Point of View.PDF by Jose A. Egea (7314389)

“…Climate change is already producing an increase in average temperatures with special intensity in certain areas like the Mediterranean ones. These changes lead to a decrease in the accumulated chill, which can have a profound impact on the phenology of Prunus species like stone fruits due to, e.g., difficulties to cover the chilling requirements to break endodormancy, the occurrence of late frost events, or abnormal early high temperatures. …”

Summary of body deformations taking into account species, size, environment and their interaction. by Emmanuel Corse (402278)

Data Sheet 1_Polarization of Vδ2 T cells to a Th2-like phenotype promotes plasmablast differentiation and possesses pro-fibrotic properties in IgG4-related disease.docx by Jieqiong Li (327149)

“…</p>Results<p>Patients with IgG4-RD exhibited decreased peripheral Vδ2 T cells displaying a Th2-like phenotype characterized by elevated Th2 cytokine production and activated IL-21—STAT3—Blimp-1—GATA3 pathway. …”

Proportion of PUD DALYs and deaths attributable to smoking by gender, SDI quintile, and GBD region in 1990 and 2021. by Wende Hao (10315597)

Predicted trends in Age-standardized rates of PUD for both sexes globally over the next 19 years (2022-2040). by Wende Hao (10315597)

Image_6_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

Image_1_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

Image_7_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

Image_4_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

Image_8_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”