Efficacy of Neonatal HBV Vaccination on Liver Cancer and Other Liver Diseases over 30-Year Follow-up of the Qidong Hepatitis B Intervention Study: A Cluster Randomized Controlled T... by Chunfeng Qu (114656)

“…The participation rates of the two surveys were 57.5% (21,770) and 50.7% (17,204) in the vaccination group and 36.3% (12,184) and 58.6% (17,395) in the control group, respectively. …”

Interaction between NP fragment 146–185 and PB2 involves PB2 amino acids 601 to 607. by Ho-Pan Hsia (4768638)

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice by Guillaume P. Dugué (620333)

“…<i>In vivo</i>, the photoactivation of dorsal raphe serotonergic neurons gave rise to a prominent light-evoked field response that displayed some sensitivity to a 5-HT1A agonist, consistent with autoreceptor inhibition of raphe neurons. …”

Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

“…K562 and K562-R cells were treated with 9nM bortezomib and 8nM BI 2536 for 60h, followed by the detection of Bcr-Abl and phosphorylated STAT5. The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”

RNF5 loss decreases ERK and Akt activation, CDK1 and Smo expression and KSHV lytic replication in PEL cells. by Xiaojuan Li (351842)

TachypleginA treatment causes a decrease in the motor activity of the TgMyoA motor complex. by Aoife T. Heaslip (207534)

Establishment of HIV latency correlates with elevated amounts of AcH4 and Brd4 but drastically decreased AcH3 content on viral LTR. by Zichong Li (5131241)

The <i>P[syt^P-L]</i> mutation decreases the Ca²⁺ affinity of release and vesicular release probability, but the readily releasable pool is unchanged. by Mallory C. Shields (4474210)

“…<p>(A) Mean EJP amplitudes from <i>+/-;P[syt^WT]/+</i> (filled black circles) and <i>+/-;P[syt^P-L]/+</i> (filled red circles) larvae at Ca²⁺ levels ranging from 0.05 mM—5.0 mM. …”

Loss of RBM-26 function causes a reduction in the density of mitochondria in the PLM axon. by Tamjid A. Chowdhury (14149846)

PB + PER exposure decreased SYP staining in the hippocampi and cerebral cortices of exposed mice. by Zuchra Zakirova (431614)

Heterogeneity of HASM membrane potential responses evoked by procontractile agonists co-treated with TAS2R agonists. by Blanca Camoretti-Mercado (762326)

Simulated regional mean wetland seasons. by Nic Gedney (19762301)

Rotenone exposure decreases GSH level in porcine oocytes. by Geun Heo (14185618)

SQFZ reverses constitutive and PI3K pathway-induced cisplatin resistance. by Bin Yan (32980)

20E repressed ILP-mediated cell membrane translocation of HaP60 and HaP110, dephosphorylated HaP60 and HaP110, and decreased their interaction. by Yu-Qin Di (8752317)

“…Green, HaP60 or HaP110; red, cell membrane stained with WGA; blue, nuclei stained with DAPI; merge, overlapped green, blue, and red fluorescence. Bar, 50 μm. <b>C.</b> Co-IP assay showed that 20E decreased the HaP60–HaP110 interaction and induced dephosphorylation in cells. …”

Comparison of mean daily IAA intake quantity before and after digestibility adjustments. by Bi Xue Patricia Soh (21100364)

Subjects:

Omega-3 enriched oils dose-dependently decrease macrophage lipid uptake. by Agua Sobrino (368634)

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

TNFAIP9 expression was increased in mice with chronic kidney disease (CKD) induced by 5/6 nephrectomy (Nx). by Ying Chen (9697)