Showing 4,061 - 4,080 results of 106,627 for search '(( 5 ((ng decrease) OR (a decrease)) ) OR ( 50 ((we decrease) OR (mean decrease)) ))', query time: 1.67s Refine Results
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    Image1_Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models.jpg by Karthikeyan Selvarasu (14004867)

    Published 2022
    “…Here, we reported that the kinesin-I heavy chain (KIF5B), a key molecular motor protein, is involved in tau homeostasis in AD cells and animal models. …”
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    GluN2A(D731N) enhances sensitivity to endogenous proton and zinc ions. by Kai Gao (120150)

    Published 2017
    “…Di-heteromeric (h2A-D731N), one-copy and two-copy mutant tri-heteromeric (D731N/2A and D731N/D731N) receptors show a decreased current ratio, indicating enhanced proton sensitivity. …”
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    GluN2A(D731N) reduces the agonist potency. by Kai Gao (120150)

    Published 2017
    “…<p>(<b>A,B</b>) Representative TEVC recordings obtained from oocytes expressing WT GluN1/GluN2A (WT 2A) receptors (<b>A</b>) and GluN1/GluN2A(D731N) (2A-D731N) receptors (<b>B</b>) in which the currents were evoked by increasing concentrations (μM) of glutamate (in the presence of 100 μM glycine) at the holding potential of -40 mV. …”
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    <i>WDR5</i> Expression Is Prognostic of Breast Cancer Outcome by Xiaofeng Dai (793874)

    Published 2015
    “…<div><p>WDR5 is a core component of the human mixed lineage leukemia-2 complex, which plays central roles in ER positive tumour cells and is a major driver of androgen-dependent prostate cancer cell proliferation. …”
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    FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia by Xiaofeng Wang (119575)

    Published 2018
    “…Furthermore, we found that FGFR3 interacted with ATG12–ATG5 conjugate by binding to ATG5. More intriguingly, FGFR3 signaling was found to decrease the protein level of ATG12–ATG5 conjugate. …”
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