Effects of “before and after injection” of tachykinin, octopamine receptors, tachykinin receptors on olfactory responses (EAG) in antennae and quantitative real-time PCR after dsRN... by Je Won Jung (121755)

“…(<b>B</b>) Tachykinin-7 (TK-7) injection produced a significant decrease in olfactory responses phase II and phase III after injection compared to before injection (phase I) (N=5, *=p<0.001). …”

Rational Design of Copper(II)–Uracil Nanoprocessed Coordination Polymers to Improve Their Cytotoxic Activity in Biological Media by Verónica G. Vegas (11217840)

“…Indeed, the release during the hydrolysis of species containing the 5-fluorouracil moiety provokes a remarkable increase in cellular toxicity and a significant increase in ROS species formation.…”

Data acquired from testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function by Janet Storm (8266991)

“…</div><div><br></div><div>The files are as follows:</div><div><div><b>-Combined analysis data for fig 2_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig5_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig6_TEER_includes normalisation.csv</b></div><div><b>-Data for fig2A+B+C_TEER_EA cells+inhibitors+thrombin_3.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_1.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_2.csv</b></div><div><b>-Data for fig3_flow cytometry HBMEC.csv</b></div><div><b>-Data for fig4A_TEER_aPC+thrombin_all time points shown.csv</b></div><div><b>-Data for fig4B_TEER_RBC+IE+lysate_all time points shown.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#04-2+#91-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#91-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-1+#04-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-1.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-3.csv</b></div></div><div><br></div><div>The related publication investigated the hypothesis that the Thrombin-PAR1 coagulation/inflammation axis plays a significant role in barrier loss in cerebral malaria (CM), and that adjunct treatments targeting this might alleviate mortality or post-CM neurological sequelae in CM. …”

Anti-TNF therapy can reverse the age-associated increase in circulating Ly6C^high monocytes. by Alicja Puchta (845752)

“…<p>(A-B) Young mice were give 200 ng/ml of TNF intraperitoneally every other day for 3 weeks. …”

microRNA 126 Inhibits the Transition of Endothelial Progenitor Cells to Mesenchymal Cells via the PIK3R2-PI3K/Akt Signalling Pathway by Junfeng Zhang (13013)

“…</p> <p>Methods and Results</p><p>EndMT of rat bone marrow-derived EPCs was induced by TGFβ1 (5 ng/mL) for 7 days. miR-126 expression was depressed in the process of EPC EndMT. …”

Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols by Yuh Shiwa (512008)

“…We then considered cell-type composition as a possible cause of the observed bias in DNA methylation profiles and found that the bias associated with the cold storage condition was largely decreased (λ_adjusted = 1.14) by taking into account a cell-type composition variable. …”

Profiling Plasma Peptides for the Identification of Potential Ageing Biomarkers in Chinese Han Adults by Jiapeng Lu (153024)

“…In particular, apolipoprotein A-I (ApoA1) concentration gradually increased between 18 to 50 years of age, the levels of fibrinogen alpha (FGA) decreased over the same age span, while albumin (ALB) was significantly degraded in middle-aged individuals. …”

Ca²⁺-induced inhibition of ferrocytochrome <i>c</i> oxidase activity in mitochondria. by Tatiana Vygodina (456671)

“…(<b>C</b>) Concentration dependences of the Ca²⁺-induced inhibition of COX and spectral shift of heme <i>a</i> in rat liver mitochondria. Cytochrome <i>c</i>²⁺ oxidation was measured as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074436#pone-0074436-g007" target="_blank"><b>Figure 7B</b></a>, trace <i>1</i> at different concentrations of free calcium buffered with 5 mM HEDTA or 5 mM NTA. …”

Image 2_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg by Caressa Hui (19676509)

“…For the entire VMAT-TBI cohort, lung Dmean, kidney Dmean, and lens Dmax were spared to 60.6% ± 5.0%, 71.0% ± 8.5%, and 90.1% ± 3.5% of prescription, respectively. …”

Image 1_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg by Caressa Hui (19676509)

“…For the entire VMAT-TBI cohort, lung Dmean, kidney Dmean, and lens Dmax were spared to 60.6% ± 5.0%, 71.0% ± 8.5%, and 90.1% ± 3.5% of prescription, respectively. …”

Quantitative Comparison of Constitutive Promoters in Human ES cells by Karin Norrman (242990)

“…The ACTB promoter was superior by maintaining expression in 75–80% of the cells after 50 days in culture. During embryoid body (EB) differentiation, promoter activities of all five promoters decreased. …”

Data_Sheet_1_Interlimb Coordination Performance in Seated Position in Persons With Multiple Sclerosis: Reduced Amplitude Over 6 min and Higher Coordination Variability in Persons W... by Mieke Goetschalckx (11585116)

“…A significant group^∗time interaction effect was found for movement amplitude, represented by a significant decrease in movement amplitude in the WF group from minute 1 to the end of the task.…”

Reduced cholinergic Ca2+ response in differentiated myotubes from SMA patients. by Nicole Hellbach (5562965)

“…These ratios were normalized to maximal values within an experiment. Data represented as mean ± SEM (A, B) and mean ± SEM of n = 6–8 individual samples from two independent experiments. *: p < 0:05, **: p < 0:01, ***: p < 0:001, two-tailed unpaired Student's t-test.…”

Poly (A) Binding Protein Cytoplasmic 1 Is a Novel Co-Regulator of the Androgen Receptor by Kurtis Eisermann (95302)

“…The NTD of the AR plays a key role in AR transactivation including androgen-independent activation of the AR in castration-resistant prostate cancer (CRPC) cells. We recently reported that amino acids (a.a.) 50-250 of the NTD are capable of modulating AR nucleocytoplasmic trafficking. …”

Table1_Label-free multimodal nonlinear optical microscopy reveals features of bone composition in pathophysiological conditions.DOCX by Benedetta Talone (11984215)

Image_1_Myeloid-Derived Suppressor Cells in Lung Transplantation.JPEG by Tobias Heigl (6636725)

“…CD4 and CD8 cells proliferation decreased by 50 and 80% if co-cultured with MDSCs (1:6 and 1:2 MDSC:T-cell ratio, respectively). …”

Illustrations of different normalizations of single-trial cross projections. by Kai J. Miller (8846117)

“…<b>A</b>. Un-normalized projections <i>V</i>_<i>k</i>(<i>t</i>)<i>V</i>_<i>l</i>(<i>t</i>) are sub-optimal because trials with large amplitude are over-emphasized in comparison with trials of lower amplitude but more characteristic structure. …”

Homoleptic Cyclometalated Iridium Complexes with Highly Efficient Red Phosphorescence and Application to Organic Light-Emitting Diode by Akira Tsuboyama (1921528)

“…The complexes studied have the general structure Ir(III)(C−N)₃, where (C−N) is a monoanionic cyclometalating ligand:  2-(5-methylthiophen-2-yl)pyridinato, 2-(thiophen-2-yl)-5-trifluoromethylpyridinato, 2,5-di(thiophen-2-yl)pyridinato, 2,5-di(5-methylthiophen-2-yl)pyridinato, 2-(benzo[<i>b</i>]thiophen-2-yl)pyridinato, 2-(9,9-dimethyl-9<i>H</i>-fluoren-2-yl)pyridinato, 1-phenylisoquinolinato, 1-(thiophen-2-yl)isoquinolinato, or 1-(9,9-dimethyl-9<i>H</i>-fluoren-2-yl)isoquinolinato. …”

Comparison of the p-values of YAP N/C ratio on different stiffnesses of substrates during the first 10 hours of the spreading process. by Qin Luo (2182514)

“…<p>(<b>A</b>) The p-values of the YAP N/C ratio on 2-kPa substrates and 5-kPa substrates (red dots) increased from 0.1725 at 0^th hour to 0.9642 at 4^th hour and decreased to 0.3103 at 10^th hour. …”

Caddisfly biodiversity in Pernambuco state, Brazil: overcoming the biodiversity knowledge shortfall and insights into the effects of climate change by Rafael Pereira (6635264)