DataSheet_1_Gut Microbiota Dysbiosis Induced by Decreasing Endogenous Melatonin Mediates the Pathogenesis of Alzheimer’s Disease and Obesity.docx by Boqi Zhang (8717811)

“…Correlation analysis revealed that systemic inflammation may be related to the increase of Ruminiclostridium_5 relative abundance. 8-month-old EMR mice had AD-like phenotypes, including Iba-1 activation, A β protein deposition and decreased spatial memory ability. …”

MAVS deficient mice display decreased polyclonal CD8⁺ T cell responses and increased viral loads in the lungs. by Matheswaran Kandasamy (105167)

Phylogenetic analysis does not reveal differences in SARS-CoV-2 sequences from vaccinated and unvaccinated individuals. by Ludy R. Carmola (20978107)

Data_Sheet_1_Secondhand Smoke Decreased Excitability and Altered Action Potential Characteristics of Cardiac Vagal Neurons in Mice.PDF by Junqing Sun (4688998)

“…Perfusion with apamin (20 nM) magnified these SHS-induced effects, suggesting reduced SK channel activity may serve to minimize the SHS-induced decreases in CVNs excitability. Medium afterhyperpolarization (a measurement of SK channel activity) was smaller in the SHS group, further supporting a lower SK channel activity. …”

Image_5_MiR-451a and let-7i-5p loaded extracellular vesicles attenuate heme-induced inflammation in hiPSC-derived endothelial cells.jpeg by Justin J. Thomas (14292593)

“…This inflammatory response was attenuated by exposure with miR-451a or let-7i-5p-loaded EVs. We also found a decrease in transcription of ICAM1 and P-Selectin, as well as the secretion of key inflammatory cytokines (e.g., CXCL10, TNF-α, and IFN-γ). …”

Changes in net primary PM_2.5 emissions are impacted substantially more by changes in vehicle emissions in comparison to changes in emissions from electric generating uni... by Jaye Mejía-Duwan (15401425)

Downregulation of <i>TcPiezo1</i> expression decreases Ca²⁺ entry in <i>T. cruzi.</i> by Guozhong Huang (673424)

“…<p>Intracellular Ca²⁺ concentrations of 5 × 10⁷ <i>TcPiezo1 Tet-OFF</i> epimastigotes (A-C) or 2 x 10⁷ trypomastigotes (D) expressing jGCaMP7s were measured by jGCaMP7s signal fluorescence in arbitrary units of fluorescence (AU). …”

Sumoylation of Sp1 repressed <i>LEDGF/p75</i> gene transcription by decreasing the abundance of Sp1 to DNA. by Dhirendra P. Singh (164293)

Primary human KIR2DL5⁺ NK cells are inhibited by CD155-expressing target cells. by Pia Fittje (12936621)

ISA27 induces the stabilisation of p53 protein levels by decreasing the interaction of p53 with MDM2 in GBM cells. by Barbara Costa (447711)

Enhanced Nrf2 activity decreases fatty acid transport and results in increased fatty acids content in white adipose tissue. by Jialin Xu (40952)

Decreased expression of the γ-glutamylcysteine ligase and increased hepatic oxidant generation and protein oxidative damage at Day+4 in Allo BMT. by Jung H. Suh (523844)

Data Sheet 1_Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection.docx by Ping-Chang Lin (2848379)

“…We performed a cell viability assay, median tissue culture infection dose (TCID₅₀) assay, and qRT‒PCR, and calculated the virus titers using the Reed-Muench method to evaluate the inhibitory effects of aqueous and alcohol HSEs on SARS‒CoV‒2 and explore the possible underlying mechanisms.…”

Fig3-5 by Yuki Iwachido (12079661)

Data Sheet 2_Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE.pdf by Mi-Ae Lyu (20413646)

“…</p>Results<p>In a dose-dependent manner, ruxolitinib addition synergizes with UCB-Tregs to suppress SLE-PBMC proliferation, inhibit CD8⁺ T cells, and reduce phosphorylation of STAT3/STAT5/AKT in CD8⁺ T cells. …”

Data Sheet 3_Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE.pdf by Mi-Ae Lyu (20413646)

“…</p>Results<p>In a dose-dependent manner, ruxolitinib addition synergizes with UCB-Tregs to suppress SLE-PBMC proliferation, inhibit CD8⁺ T cells, and reduce phosphorylation of STAT3/STAT5/AKT in CD8⁺ T cells. …”

Data Sheet 1_Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE.pdf by Mi-Ae Lyu (20413646)

“…</p>Results<p>In a dose-dependent manner, ruxolitinib addition synergizes with UCB-Tregs to suppress SLE-PBMC proliferation, inhibit CD8⁺ T cells, and reduce phosphorylation of STAT3/STAT5/AKT in CD8⁺ T cells. …”

Impaired glucose metabolism and decreased insulin sensitivity in isolated adipocytes of Nscl-2−/−, Nscl-2−/−×ob/ob mice and controls. by Karen Ruschke (372824)

<i>ogt-1; eel-1 +</i> Pan-neuronal OGT-1 have decreased sensitivity to electroshock and improved locomotion. by Nirthieca Suthakaran (11731101)

“…<p>Shown are each genotype ran through the electroconvulsive seizure assay for 3 seconds at 47V in saline control group. (A) Average time of recovery was significantly decreased in <i>ogt-1; eel-1</i> + Pan-neuronal OGT-1 worms, <i>Ogt-1(ok430) III; eel-1(bgg1) IV; bggSi2[Prab-3</i>::<i>ogt-1a] II</i> (n = 33), in comparison to <i>ogt-1;eel-1</i> double mutants (n = 30) but not significantly different from <i>eel-1</i> null mutants (n = 26). …”

<i>Cin85</i>-Deficiency results in defective clearance of LCMV-c13 and is correlated with decreased neutralizing antibody titer. by Saravanan Raju (5181014)