Transitioning of people with T1D from Multiple Daily Injections (MDI) and Self-Monitoring of Blood Glucose (BGM) directly to MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system... by Bartłomiej Matejko (13180606)

“…</p> <p>Results: 41 participants were recruited and randomized to either the AHCL (20) or the MDI+BGM (21) group. 37 participants (age 40.3±8.0 years; duration of diabetes 17.3 ± 12.1 years; BMI 25.1±3.1 kg/m2; HbA1c 7.2% ± 1.0) completed the study. Time spent in target (TIR) increased from 69.3±12.3% at baseline to 85.0±6.3% at 3 months in the AHCL group, while remaining unchanged in the control group: treatment effect 21.5% [95% CI 15.7, 27.3%]; p < 0.001. …”

Targeting hTERT Promoter G‑Quadruplex DNA Structures with Small-Molecule Ligand to Downregulate hTERT Expression for Triple-Negative Breast Cancer Therapy by Wei Long (411482)

“…Ligand <b>5</b> showed high affinity toward hTERT G4 (<i>K</i>_d = 1.1 μM) and potent activity against triple-negative breast cancer cells (MDA-MB-231, IC₅₀ = 1 μM). …”

Data_Sheet_1_Mental Health in German Paralympic Athletes During the 1st Year of the COVID-19 Pandemic Compared to a General Population Sample.docx by Aglaja Busch (9922233)

“…In para-athletes, no significant and a weak positive correlation was found between decreased training load and PHQ-4 values and a stress level, respectively. …”

After the injection of PAM, the level of PPARγ increases, and the expression of TGFβ1/SMAD3 decreases, thereby inhibiting EMT and improving intestinal fibrosis. (A) Changes in the mRNA expression level of E-cadherin. (B) Changes in the mRNA expression level of N-cadherin. (C) Changes in the mRNA expression level of V-cadherin. (D) Changes in the mRNA expression level of COL1A1.... by Yi You (2567890)

“…(C) Changes in the mRNA expression level of V-cadherin. (D) Changes in the mRNA expression level of COL1A1. …”

IL-1Ra ASO treatment in HFD-fed obese mice results in decreased body weight (A) despite similar food intake (B) (food intake measured weekly and presented as average food intake ov... by Niclas Franck (632562)

Supplementary Material for: Downregulation of N-Acetylglucosaminyltransferase GCNT3 by miR-302b-3p Decreases Non-Small Cell Lung Cancer (NSCLC) Cell Proliferation, Migration and In... by Li Q. (2850350)

Immunofluorescence staining patterns for 5-mC and 5-hmC in CIN3 lesions with overlying columnar epithelium, showing extensive heterogeneity for methylation and hydroxymethylation. by Jobran M. Moshi (18405149)

“…In <b>C</b> and <b>E</b> +: indicates areas with an increased 5-hmC immunostaining as compared to * indicating areas with a decrease of 5-hmC immunostaining.…”

Flow diagram of participant selection. by Prajwal Paudel (7359209)

“…Lack of exposure to ACS was associated with higher odds of prolonged hospital stay (aOR: 3.321, 95% CI: 1.957–5.638) and mortality (aOR: 5.731, 95% CI: 3.199–10.266).…”

Supplementary file ACS. by Prajwal Paudel (7359209)

“…Lack of exposure to ACS was associated with higher odds of prolonged hospital stay (aOR: 3.321, 95% CI: 1.957–5.638) and mortality (aOR: 5.731, 95% CI: 3.199–10.266).…”

Decreasing <i>VCP</i> function increases the activation of the Ire1/Xbp1 UPR pathway in <i>Rh1^P37H</i>-expressing flies. by Ana Griciuc (243073)

Cancer cells internalized efficiently hESCs-Exo. by Shufeng Zhou (398572)

pGenesil-siSurvivin and pGenesil-shiHBV4 have synergistic effects in decreasing the survivin protein level and inducing apoptosis of HepG2.2.15 cells. by Jingwei Ma (125700)

Dataset_Plos_weighting_def - by Jesús Martín-Fernández (406234)

“…The probability of reporting a “very good” health condition decreased with a diagnosis of hypertension (6.2%; CI 95%: 3.1–9.3%) and hypertensive medication (4.5%; CI 95%: 1.8–7.3%). …”

Targeting of Alpha-V Integrins Reduces Malignancy of Bladder Carcinoma by Geertje van der Horst (458926)

“…<div><p>Low survival rates of metastatic cancers emphasize the need for a drug that can prevent and/or treat metastatic cancer. αv integrins are involved in essential processes for tumor growth and metastasis and targeting of αv integrins has been shown to decrease angiogenesis, tumor growth and metastasis. …”

Loss of cytoplasmic incompatibility in <i>Wolbachia</i>-infected <i>Aedes aegypti</i> under field conditions by Perran A. Ross (844275)

“…We reared <i>w</i>Mel-infected <i>Ae</i>. <i>aegypti</i> larvae in the field during the wet season in Cairns, North Queensland. …”

Supplemental Figure S2 from Evolutionary Action Score of <i>TP53</i> Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and... by David M. Neskey (14920268)

Supplemental Figure S1 from Evolutionary Action Score of <i>TP53</i> Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and... by David M. Neskey (14920268)

Supplemental Figure S3 from Evolutionary Action Score of <i>TP53</i> Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and... by David M. Neskey (14920268)

Supplemental Figure S4 from Evolutionary Action Score of <i>TP53</i> Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and... by David M. Neskey (14920268)

<i>SU-like sensitive</i> and <i>SU-like VRC26 early escape</i> viruses are differently neutralized post CD4 attachment. by Lucia Reh (546554)