5-HT-induced cardiomyocyte injury required the presence GC or NE <i>in vitro</i>. by Wang Xinxing (523139)

“…</b> The cell viability of cardiomyocytes treated with 10⁻⁸ M 5-HT and 10⁻⁶ M GC decreased significantly compared with the control. …”

The Ca²⁺/PKC/p115 signaling axis enables persistent RhoA signaling. by Jason Z. Zhang (9339291)

“…<p>(<b>A</b>) HeLa cells expressing various proteins and treated with various drugs to increase or decrease flux into the Ca²⁺/PKC/p115 signaling axis. …”

Levels of circulating heparan sulfate-fragments in murine sepsis. by Lukas Martin (747245)

Reply to Jüni and colleagues regarding “Converting standardized mean differences to dichotomous outcomes: A comment on the Cochrane review ‘Intra-articular corticosteroid for knee... by Martin Mayer (6509486)

“…Jüni and colleagues specify interest in patients reaching C or lower for both pain and function: For their specified response outcomes of achieving ≥50% improvement in pain and function, they specify control group probabilities of 31% and 22%, respectively (I use 22% here given their acknowledgment that 26% is incorrect), and these probabilities are based on achieving decreases of at least 1.2 standard deviation (SD) units (C = -1.2 SD units or lower) and at least 1.35 SD units (C = -1.35 SD units or lower), respectively.[3,5–7] </p> <p> </p> <p>Because of this, it is incorrect for Jüni and colleagues to use π/√3 (≈ 1.81) for the conversion factor, and I show this in my previous correspondence (the correct conversion factor is –π/√3 ≈ –1.81).[2,4] Consequently, their statement that using π/√3 is technically or formally correct for the outcome of preventing one additional non-response is also incorrect. …”

RipE1 undergoes phosphorylation in <i>N. benthamiana</i>, which contributes to protein stability. by Wenjia Yu (9422059)

Properties of acetylcholine-induced [Ca²⁺]i elevation in SH-SY5Y cells. by Tamayo Takahashi (9706873)

“…Compared with the outcome of acetylcholine treatment alone, the [Ca²⁺]i was steeply elevated but was quickly decreased. In both (A) and (B), a representative of 5 independent trials is shown. …”

Cell surface sialic acid is not required for SARS-CoV-2 spike glycoprotein binding. by Kimberley C. Siwak (20378620)

Role of NOS isoforms in VEGF overexpressed lung on the vascular markers CD31 and vWF. by Mansoor A. Syed (847484)

“…Similarly another vascular marker vWF showed decreased staining VEGF-TG+/ NOS2^−/− (<b>E</b> and <b>F</b>) and VEGF-TG/ NOS3^+/− (<b>G</b> and <b>H</b>) mice lungs as compared to VEGF TG+ lungs. …”

Relative mRNA expression of heparanase. by Lukas Martin (747245)

HS induces a rapid degeneration of the nuclei of the MB neurons in the absence of dPGAM5. by Yosuke Ishida (185168)

“…<p>The number of cell bodies of the KCs decreases in HS-treated <i>PGAM5¹</i> flies. …”

Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation-5 by Tae Hyeon Koo (77248)

“…D. Expression of EFA6 decreases the interaction between Arf6 and Kalirin5. …”

<i>osm-5</i> acts in ASH to regulate neuronal response of ASH to 2-nonanone. by Wenxing Yang (1491607)

“…<p><b>(A—D)</b> Exposure to 2-nonanone (Nona) increases GCaMP signal of ASH (ON response) and removal of 2-nonanone decreases it (OFF response). The <i>osm-5(p813)</i> mutation disrupts both the ON and OFF responses and expressing <i>osm-5</i> in ASH rescues the defects. …”

Cdk5 Gain- or Loss-of-Function Does Not Affect the Proliferation and Differentiation Capacity of Adult NPCs by Sebastian Jessberger (269496)

“…<div><p>(A–E) Stable transduced cell lines expressing a control virus (A), <i>cdk5</i> (B), <i>cdk5</i> plus coelectroporation with <i>p35</i> (red in [C]), and <i>DNcdk5</i> (D) showed no statistically significant differences in BrdU (red in [A, B, and D], blue in [C]) uptake after a 1-h pulse (E). …”

Image 5_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…The study population comprised 79.5% females and 20.5% males, with a mean age of 63 years and an average disease duration of 15.2 years.…”

PXT3003 therapy acting on Pmp22 overexpression and downstream signalling in long-term at 12 weeks. by Thomas Prukop (6236186)

“…At the end of long-term observation, PXT3003 early short-term treatment restored the decreased p-AKT/AKT signalling in CMT1A rats (H; WT controls 1.00±0.17, CMT1A controls 0.38±0.08, CMT PXT3003-3 0.93±0.21) and dose-dependently corrected the disrupted ratio of p-AKT/AKT to p-MAPK/MAPK signalling towards the wildtype situation (I; CMT1A controls 0.30±0.08, CMT PXT3003-1 0.56±0.15, CMT PXT3003-2 0.85±0.13, CMT PXT3003-3 1.36±0.52), which is characterized by a higher relative amount of p-AKT versus p-MAPK. …”

Characterisation of the effect of diet composition on C57BL/6 mice. by Tara Jois (3592874)

Effect of CA on glucose uptake. by Lucia Natarelli (823310)

ROC analysis for differentiating bladder cancer patients from controls using the ucfDNA concentration before and after normalization by creatinine concentration in those samples wi... by Meihui Chen (1670020)

Factors associated with stunting in healthy children aged 5 years and less living in Bangui (RCA) by Pascale Vonaesch (149522)

“…Although its global prevalence is slowly decreasing, the actual number of affected children is still rising in Sub-Saharan Africa. …”

Coral juvenile abundance of the most abundant taxa across locations and years. by Anna Koester (11805572)