CSF/plasma levels, transthyretin stabilisation and safety of multiple doses of tolcapone in subjects with hereditary ATTR amyloidosis by Yusuke Takahashi (19844)

Image1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.tif by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”

Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”

Supplementary Material for: No short term effect of low dose nicotine on inflammation after global hypoxia in newborn piglets by Volstad K.B. (19515523)

Exposure to particle debris generated from passenger and truck tires induces different genotoxicity and inflammatory responses in the RAW 264.7 cell line by Anna Poma (835467)

“…In MTS assay, after 24 hours, it was found that PP induced a 30% decrease in metabolic activity at a concentration of 10 μg/ml, while TP caused reductions of 20% and 10% at concentrations of 10 μg/ml and 50 μg/ml, respectively. …”

Table_2_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Niamh Phelan (10450682)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Table_2_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Phelan Niamh (10342460)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Table_1_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Niamh Phelan (10450682)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Table_1_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Phelan Niamh (10342460)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Table_2_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.XLSX by Tatiana E. Deniskova (5527175)

“…Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Data_Sheet_4_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.PDF by Tatiana E. Deniskova (5527175)

“…Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Table_1_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.XLSX by Tatiana E. Deniskova (5527175)

“…Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Data_Sheet_3_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.PDF by Tatiana E. Deniskova (5527175)

“…Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Data_Sheet_6_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.PDF by Tatiana E. Deniskova (5527175)

“…Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Data_Sheet_1_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.PDF by Tatiana E. Deniskova (5527175)

“…Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Data_Sheet_2_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.PDF by Tatiana E. Deniskova (5527175)

“…Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

The contributions of the saturable and non-saturable components to total flux of [³H]-ADMA into the capillary depletion samples are plotted against the unlabelled ADMA c... by Mehmet Fidanboylu (343341)

“…<p>The measured values are the mean ±SEM for 4-5 mice (homogenate), 4-5 mice (supernatant) and 5 mice (pellet except at 100 μM where it was 1 mouse) at each of the 6 ADMA concentrations and has been [¹⁴C]-sucrose corrected. …”

Image_1_Immune Protective Evaluation Elicited by DNA Vaccination With Neospora caninum Dense Granules Proteins in Mice.TIF by Guili Yu (10201136)

“…The immune protective efficacy revealed that pcNcGRA4, pcNcGRA14, and pcNcGRA17 DNA vaccines could individually increase the survival rate to 50, 37.5, and 25% in comparison with 0% in the control group; prolong the survival time more than 20.88 ± 11.12, 18.88 ± 10.83, and 16.63 ± 10.66 days compared with the control group of 4 ± 1.31 days; and decrease parasite burden in the brains to 297.63 ± 83.77, 471.5 ± 110.74, and 592.13 ± 102.2 parasites/100 ng comparing with 1221.36 ± 269.59 parasites/100 ng in the control group. …”

Dose planning study of proton versus photon radiotherapy for head and neck squamous cell carcinoma of unknown primary in the primary and recurrent setting by Anne Ivalu Sander Holm (3996290)

“…However, using protons for re-irradiation only leads to a decrease in the tissue volume receiving a specific dose outside the target overlapping region, e.g., V90Gy_mean was 31, 25, and 22 cm³ for photons-photons, photons-protons, and protons-protons, respectively. …”

Figure S6 from Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma <i>In Vitro</i> and Patient-Derived Xenografts <i>In Vivo</i> by Mengqiu Song (8858807)

“…Tumor volume was measured twice a week. The asterisk (* p < 0.05) indicates a significant decrease in volume of tumors from oridonin-treated mice compared to vehicle-treated mice. …”