Mechanical AVR With Y-Incision Aortic Annular Enlargement by Bo Yang (104813)

“…</p> <p><strong>Patient Selection</strong> </p> <p>The patient was a female with a body height of 155 cm (5’11”), a body weight of 126 kg (277 pounds), a BMI of 52.5 kg/m2, and a body surface area of 2.15 m2. …”

Salinomycin impairs HCC cell survival. by Johannes Klose (562050)

“…<p>HepG2 and Huh7 cells were exposed to increasing concentrations of Salinomycin (1, 2, 5 and 10 µM) for 24 hours. (<b>A</b>) Cell viability was assessed by MTS-assay; high concentrations of Salinomycin led to significantly decreased viability of both cell lines (n = 5). …”

Data_Sheet_1_Concerted suppressive effects of carisbamate, an anti-epileptic alkyl-carbamate drug, on voltage-gated Na+ and hyperpolarization-activated cation currents.docx by Te-Yu Hung (15861305)

“…However, CRS strongly decreased the strength (i.e., Δarea) of the nonlinear window component of I_Na (I_Na(W)), which was activated by a short ascending ramp voltage (V_ramp); the subsequent addition of deltamethrin (DLT, 10 μM) counteracted the ability of CRS (100 μM, continuous exposure) to suppress I_Na(W). …”

Mcl-1 plays critical roles in regulating the sensitivity of melanoma cells to apoptosis induced by EGb761. by Yufang Wang (105742)

“…<p>(A) Knockdown of Mcl-1by siRNA decreases the levels of Mcl-1expression. …”

Data_Sheet_1_Severe Disease in Patients With Recent-Onset Psoriatic Arthritis. Prediction Model Based on Machine Learning.docx by Rubén Queiro (8445777)

“…Objectives<p>To identify patient- and disease-related characteristics that make it possible to predict higher disease severity in recent-onset PsA.</p>Methods<p>We performed a multicenter observational prospective study (2-year follow-up, regular annual visits). …”

DataSheet2_Rejuvenation of Helicobacter pylori–Associated Atrophic Gastritis Through Concerted Actions of Placenta-Derived Mesenchymal Stem Cells Prevented Gastric Cancer.PDF by Jong Min Park (3387806)

“…Significant changes in various pathological parameters including inflammation, gastric atrophy, erosions/ulcers, and dysplastic changes were noted in the control group (p < 0.01), but these were all significantly reduced in the PD-MSC/CM-treated groups. Lgr5+, Ki-67, H⁺/K⁺-ATPase, and Musashi-1 expressions were all significantly increased in the treated animals, while inflammatory mediators, MMP, and apoptotic executors were significantly decreased in the PD-MSC group compared to the control group (p < 0.001). …”

DataSheet1_Rejuvenation of Helicobacter pylori–Associated Atrophic Gastritis Through Concerted Actions of Placenta-Derived Mesenchymal Stem Cells Prevented Gastric Cancer.DOCX by Jong Min Park (3387806)

“…Significant changes in various pathological parameters including inflammation, gastric atrophy, erosions/ulcers, and dysplastic changes were noted in the control group (p < 0.01), but these were all significantly reduced in the PD-MSC/CM-treated groups. Lgr5+, Ki-67, H⁺/K⁺-ATPase, and Musashi-1 expressions were all significantly increased in the treated animals, while inflammatory mediators, MMP, and apoptotic executors were significantly decreased in the PD-MSC group compared to the control group (p < 0.001). …”

MSC^hUCB1 express neural specific markers suggesting neural differentiation. by Murni Tio (197880)

“…The MAPK pathway is down-regulated as a consequence of differentiation as shown by decreasing levels of P-ERK1/2 correlated to increasing length of differentiation. …”

Reduction in DRG neuronal numbers following error correction. by Ayal Ben-Zvi (438134)

“…A significant decrease in neuron number is observed in the Sema3A^−/−:BAX^−/− embryos as compared to Sema3A^+/+: BAX^−/−, which correlates with error correction (P = 0.0169). …”

Demography of normoxic and hypoxic flies by Paul Vigne (373124)

“…</p> <p>(A) Survivorship analysis.</p> <p>Hypoxia decreased the mean life span from 33.6±0.8 days (n = 79) to 6.3±0.1 days (n = 282).…”

COMPARISON OF RESPONSE SURFACE METHODOLOGY (RSM) AND ARTIFICIAL NEURAL NETWORKS (ANN) TOWARDS EFFICIENT OPTIMIZATION OF FLEXURAL PROPERTIES OF GYPSUM-BONDED FIBERBOARDS by Morteza Nazerian (5256530)

“…The weight ratios of fiberglass (at three levels 0, 3 and 6%), bagasse fiber (at three levels 0, 7.5 and 15%) and kenaf fiber (at three levels 0, 7.5 and 15%) to gypsum are used to make the gypsum-bonded fiberboard with the nominal density 1.10 g.cm-3 . …”

Altered membrane properties and reduced stability of RBC_VL after sensitization with anti-9-<i>O</i>-AcSGP IgG_VL antibodies. by Sajal Samanta (148083)

“…FCS was measured of RBC_N (upper left panel) and of RBC_VL without sensitization (upper right panel) or with sensitization with anti-9-<i>O</i>-AcSGP IgG_VL (2.5 µg/ml) (lower left panel) or treatment with A23187 (1.0 µM) (lower right panel). …”

LIG treatment reduced T98G single cell migration capacity. by Jun Yin (94374)

“…<b>B</b>) The mean square displacement (MSD) vs. time interval is shown as a log-log plot, demonstrating that LIG treatment significantly decreases the slope of the MSD of T98G cells as compared to control conditions. …”

Confirmation that ΔRE values reflect potential for escape from CTLs. by Aleksandr M. Gorin (4336666)

“…<p>Clonal HIV-1_NL4-3 with five SL9 epitope variants with increased (1.39–1.66 and 1.37–2.32 for CTL clones 3.23T and 10.11T respectively), one variant with decreased (-1.42 and -1.43 with CTL clones 3.23T and 10.11T respectively) ΔRE, and the subtype B consensus epitope were individually tested for susceptibility for suppression by CTLs. …”

The effect of the PI3K inhibitor LY294002 (LY) on the cell viability and the [Ca²⁺]_i of primary cultured SD rat retinal cells in H₂O₂ in... by Yan Feng (128912)

“…<p>A: Western blot results of the activation of the PI3K/Akt pathway after βE2 treatment for 0.5 hrs; B: Quantitative data of A; C, E, G, and I: Cell viability quantitative data; D, F, H, and J: [Ca²⁺]_i quantitative data; C and D: The effects of LY treatments for 24 hrs and 0.5 hrs on the cell viability and the resting [Ca²⁺]_i; E and F: The inhibitory effect of LY pretreatment for 0.5 hrs on the increased cell viability and [Ca²⁺]_i induced by 10 μM βE2 treatment for 0.5 hrs (10 μM LY in E, 10 μM and 20 μM LY in F); G and H: The effect of LY pretreatment for 0.5 hrs on the decreased cell viability and increased [Ca²⁺]_i induced by 100 μM H₂O₂ treatment for 2 hrs (10 μM LY in G, 10 μM and 20 μM LY in H); I and J: The dose-dependent attenuating impact of 20-50 μM LY pretreatment for 0.5 hrs on the βE2 retinal protective role against H₂O₂ injury, which is associated with the dose-dependent attenuation of the increased [Ca²⁺]_i (Protocol of drug application: LY for 0.5 hrs, E2 for 0.5 hrs and H₂O₂ for 2 hrs). …”

Image_1_Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis.JPEG by Gerjan J. Dekkema (7375049)

“…Overexpression of miR-142-3p significantly decreased cAMP levels (p = 0.02) and tended to decrease the mRNA levels of a predicted target gene, adenylate cyclase 9 (ADCY9; p = 0.06). …”

Table_4_Risk Factors and Nomogram for Predicting Relapse Risk in Pediatric Neuromyelitis Optica Spectrum Disorders.xlsx by Shanchao Zhang (500712)

“…A nomogram was generated to assess relapse attacks in 1-year follow-up. …”

Supplementary Material for: Age Dependency of Successful Recanalization in Anterior Circulation Stroke: The ENDOSTROKE Study by Singer O.C. (2884253)

Table_3_Risk Factors and Nomogram for Predicting Relapse Risk in Pediatric Neuromyelitis Optica Spectrum Disorders.xlsx by Shanchao Zhang (500712)

“…A nomogram was generated to assess relapse attacks in 1-year follow-up. …”

Table_1_Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis.pdf by Gerjan J. Dekkema (7375049)

“…Overexpression of miR-142-3p significantly decreased cAMP levels (p = 0.02) and tended to decrease the mRNA levels of a predicted target gene, adenylate cyclase 9 (ADCY9; p = 0.06). …”