Unique challenges required reassessment and alterations to critical reagents to rescue a neutralizing antibody assay by Blake A Rowe (19589318)

“…</p> <p><b>Results & conclusion:</b> A larger dynamic range, high inhibition and higher drug tolerance were achieved by adding an acid dissociation step to the assay, performing atypical biotin labeling of Drug 1 and switching to a detection target that contained an Fc linker to increase steric hinderance and decrease its binding affinity to Drug 1.…”

The impact of fishing on a highly vulnerable ecosystem, the case of Juan Fernández Ridge ecosystem - Fig 7 by Javier Porobic (6392612)

“…Note that the y-axes is the ratio of change against the starting conditions—so a -0.5 result indicates a 50% decrease and a 0.5 result indicates a 50% increase -.…”

(A and B) Immunofluorescence analysis of tumors grown in WT or Sema4D KO animals by Jose Rafael Sierra (50652)

“…In A, staining with CD45 and F4/80 (specific for macrophages) reveals that most of the leukocytes in the tumor stroma are macrophages (∼90%; not depicted). …”

Effect of triple vaccine on airway hyperresponsiveness in mice sensitized to 3 allergens. by Mey-Fann Lee (539864)

Influence of dietary and physical activity restriction on pediatric adenotonsillectomy postoperative care in Brazil: a randomized clinical trial by Denise Manica (4702840)

“…Mean age in months (A = 79.5; SD = 33.9/B = 81.1; SD = 32.6) and sex (A = 58% male; B = 64.4% male) were equivalent between groups. …”

NF-κB p65 and phosphorylation of IκBα <i>in vitro</i>. by Naoki Takada (2728912)

“…<p>(A) The enzyme-linked immunosorbent assay (ELISA) results showed that p65 concentration in the radiation group was higher than that in the control group (NOZ: 2,398.4 ± 62.8 ng/mg protein vs. 923.5 ± 42.3 ng/mg protein, p < 0.01; OCUG-1: 2,609.3 ± 409.3 ng/mg protein vs. 1,899.5 ± 99.5 ng/mg protein, p < 0.05). p65 concentration in the combination group was lower than that in the radiation group (NOZ: 1,256.1 ± 13.0 ng/mg protein vs. 2,398.4 ± 62.8 ng/mg protein, p < 0.01; OCUG-1: 1,250.9 ± 117.8 ng/mg protein vs. 2,609.3 ± 409.3 ng/mg protein, p < 0.01). …”

Image_4_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Image_2_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Image_1_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Image_3_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Mitotic regeneration of IPhCs. by Tomokatsu Udagawa (11675636)

“…(O) Significantly more EdU⁺ Sox2⁺ cells were detected throughout the P7 IPhC regions of DT-treated <i>Lgr5</i>^<i>DTR/+</i> cochlea relative to controls, decreasing in an apical–basal gradient. …”

The correlation between external apical root resorption and electric pulp test responses: a prospective clinical trial by Farnaz YOUNESSIAN (12853367)

Simulating non-small cell lung cancer with a multiscale agent-based model-2 by Zhihui Wang (88248)

“…<p><b>Copyright information:</b></p><p>Taken from "Simulating non-small cell lung cancer with a multiscale agent-based model"</p><p>http://www.tbiomed.com/content/4/1/50</p><p>Theoretical Biology & Medical Modelling 2007;4():50-50.…”

Supplementary Material for: Surfactant Treatment of Late Preterm Infants during Emergency Transport: A Retrospective, Observational Study by Cavallin F. (11448277)

“…<b><i>Results:</i></b> Surfactant was administered to 155/303 neonates (51.1%) at 3 different time points: at a referring hospital (50 neonates), when the transport team arrived (25 neonates), or at a referral hospital (80 neonates). …”

Efficacy of SGLT2 inhibitors for anthracycline-induced cardiotoxicity: a meta-analysis in cancer patients by Sana Mohsin (19773969)

“…</p> <p><b>Results:</b> 3 cohort studies were identified, analyzing 2817 patients. Results display a significant reduction in overall mortality [RR = 0.52 (0.33–0.82); <i>p</i> = 0.005; I²= 32%], HF hospitalization [RR = 0.20 (0.04–1.02); <i>p</i> = 0.05; I²= 0%] and no significant reduction in HF incidence [RR = 0.50 (0.20–1.16); <i>p</i> = 0.11, I²= 0%].…”

The Efficacy of Hyperbaric Oxygen Therapy on Middle Cerebral Artery Occlusion in Animal Studies: A Meta-Analysis by Yang Xu (178421)

“…Subgroup analysis showed that a maximal neuro-protective effect was reached when HBO was administered immediately after MCAO with an absolute atmospheric pressure (ATA) of 2.0 (50% decrease; 95% CI, 43% -57% decrease; <i>p</i> < 0.0001) and more than 6 hours HBO treatment (53% decrease; 95% CI, 41% -64% decrease; <i>p</i> = 0.0005).…”

Data_Sheet_1_Mindfulness Training for Primary Care for Portuguese-Speaking Immigrants: A Pilot Study.docx by Marcelo Trombka (11411288)

“…All survey finishers would recommend the program to a friend, found the program helpful, and rated the overall program as “very good” or “excellent,” and 93% would participate again, with satisfaction mean scores between 4.6 and 5 (Likert scale 0–5). …”

Supplementary Material for: Effects of Low-Volume, High-Intensity Interval Training Compared with Continuous Training on Regional and Global Body Composition in Adults with Metabol... by Aristizabal J.C. (11527624)

“…<b><i>Methods:</i></b> This is a post hoc analysis of the randomized clinical trial Intraining-MET. …”

Neutralization of point mutants of B.1.351 and D614G spike-pseudotyped lentiviral particles by convalescent plasmas from B.1.351 and early 2020-infected individuals. by Allison J. Greaney (11046384)

“…<b>(B)</b> The fold-decrease in neutralization for samples shown in <b><a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010248#ppat.1010248.g005" target="_blank">Fig 5</a></b>, with the addition of previously measured neutralization by samples from 6 early 2020 convalescent individuals collected approximately 100 days post-symptom onset [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010248#ppat.1010248.ref038" target="_blank">38</a>]. …”

Quantitative image analysis metrics for the 3D gridded reconstruction (SIMBA) in red, the motion-resolved reconstruction (XD-SIMBA) in purple, the motion-resolved reconstruction wi... by Ludovica Romanin (18824043)