Table_1_Clinical study on endovascular recanalization of non-acute symptomatic middle cerebral artery occlusion.XLSX by Jinchao Xia (14211707)

“…From the low- to high-risk groups, the recanalization rate gradually decreased (100.0, 91.7, and 16.7%, respectively, P = 0.020), the perioperative complication rate gradually increased (0, 13.9, and 83.3%, respectively, P < 0.001), the proportion of the modified Rankin scale scores >2 at 90 days increased (0, 11.7, and 50.0%, P < 0.001), and the restenosis/reocclusion rates in the 73 cases of successful recanalization increased (0, 16.1, and 100%, P = 0.012) during follow-up.…”

DataSheet_1_The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice.docx by Ye Qiu (363315)

“…</p>Methods<p>Eight-week-old db/db mice were treated with metformin (Met) (100 mg/kg) and CR (50 mg/kg) for eight weeks.</p>Results<p>CR treatment showed hypoglycemic functions indicated by reduced bodyweight, food and water intake, plasma glucose, and serum levels of glycated hemoglobin A1c. …”

Video_3_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

Table_1_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.docx by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

DataSheet_1_Changing trends in the disease burden of uterine cancer globally from 1990 to 2019 and its predicted level in 25 years.docx by Shuang Song (457799)

“…</p>Conclusions<p>UC has significantly impacted global health negatively, with its influence stemming from a range of factors including geographical location, age-related and racial disparities, and SDI.…”

Table_2_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Characteristics of included studies. by Jiaxuan Wen (12531339)

“…Dexmedetomidine as opposed to midazolam achieved a shorter length of stay in ICU (MD = -2.25, 95%CI = -2.94, -1.57, p<0.0001), lower risk of delirium (RR = 0.63, 95%CI = 0.50, 0.81, p = 0.0002), and shorter duration of mechanical ventilation (MD = -0.83, 95%CI = -1.24, -0.43, p<0.0001). …”

Table_4_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Subgroup analysis. by Jiaxuan Wen (12531339)

“…Dexmedetomidine as opposed to midazolam achieved a shorter length of stay in ICU (MD = -2.25, 95%CI = -2.94, -1.57, p<0.0001), lower risk of delirium (RR = 0.63, 95%CI = 0.50, 0.81, p = 0.0002), and shorter duration of mechanical ventilation (MD = -0.83, 95%CI = -1.24, -0.43, p<0.0001). …”

Data Sheet 1_Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats.docx by Baocang Yin (20689031)

“…Ethnopharmacological relevance<p>Eucommia ulmoides, recognized as a traditional Chinese medicinal herb, can tonify liver and kidney and strengthen bones and muscles. …”

Chlorogenic Acid Combined with <i>Lactobacillus plantarum</i> 2142 Reduced LPS-Induced Intestinal Inflammation and Oxidative Stress in IPEC-J2 Cells by Orsolya Palócz (3353603)

“…Treatment with chlorogenic acid (25–50 μM) significantly decreased gene expression and concentration of proinflammatory cytokines IL-6 and IL-8 compared to LPS-treated cells. …”

Flow chart of the study selection process. by Jiaxuan Wen (12531339)

“…Dexmedetomidine as opposed to midazolam achieved a shorter length of stay in ICU (MD = -2.25, 95%CI = -2.94, -1.57, p<0.0001), lower risk of delirium (RR = 0.63, 95%CI = 0.50, 0.81, p = 0.0002), and shorter duration of mechanical ventilation (MD = -0.83, 95%CI = -1.24, -0.43, p<0.0001). …”

Functional and Structural Succession of Soil Microbial Communities below Decomposing Human Cadavers by Kelly L. Cobaugh (753944)

“…During active decay (7 - 12 days postmortem), respiration and biomass production rates were high: the community was dominated by Proteobacteria (increased from 15.0 to 26.1% relative abundance) and Firmicutes (increased from 1.0 to 29.0%), with reduced Acidobacteria abundances (decreased from 30.4 to 9.8%). Once decay rates slowed (10 - 23 d postmortem), respiration was elevated, but biomass production rates dropped dramatically; this community with low growth efficiency was dominated by Firmicutes (increased to 50.9%) and other anaerobic taxa. …”

Video_2_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

DataSheet_1_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.docx by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

Image 7_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.tif by Joachim Müller (265589)

“…Interestingly, differentially abundant proteins were clearly linked to phenotypic changes associated to in vitro adaptation: loss of ability to spontaneously form cysts at high passages and decreased expression of cyst and bradyzoite markers (BAG1, Enolase 1, and SRS35A), while culture adaptation was associated with increased abundance of recognized virulence factors such as GRA15, GRA16, TEEGR and NSM.…”

Determination of the ΔCt cutoff. by Takashi Hirama (345079)

“…<p>(A) Selection of purulent sputum. Sputum was classified by its gross appearance, with 50 samples studied for each classification. …”

MiR-185 and 342 induce caspase-dependent apoptotic death. by Xiangyan Li (443886)

“…<p><b>A,</b> An Annexin V-FITC/PI staining apoptotic assay and flow cytometry were performed in LNCaP and C4-2B cells transfected with miRNAs. …”

Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near <i>CDKN2B-AS1</i>, <i>SIX6</i> and <i>GAS7</i> by Yukihiro Shiga (724428)

“…In addition, nominal correlation was observed between <i>CDKN2B-AS1</i> (rs2157719) and optic nerve head blood flow (β = -0.54 and -0.67 arbitrary units (AU), <i>P</i> = 2.00E-02 and 1.39E-02), between <i>SIX6</i> (rs33912345) and decreased total peripapillary retinal nerve fiber layer thickness (β = -2.16 and -2.82 μm, <i>P</i> = 4.68E-02 and 2.40E-02, additive and recessive model, respectively) and increased optic nerve head blood flow (β = 0.44 AU, <i>P</i> = 2.20E-02; additive model) and between <i>GAS7</i> (rs9913911) and increased cup volume (β = 0.03 mm³, <i>P</i> = 4.60E-02) and mean cup depth (β = 0.03 mm³, <i>P</i> = 4.11E-02; additive model) and decreased pattern standard deviation (β = -0.87 dB, <i>P</i> = 2.44E-02; dominant model).…”

Data Sheet 1_Pre-sowing grain treatment with bio-AgNPs stimulates plant growth and affects redox homeostasis in maize.docx by Joanna Trzcińska-Wencel (21405185)

“…Zeta potential revealed that NPs were negatively charged [-19.5 mV (61.3%) and −2.93 mV (38.6%)]. The diffractogram of AgNPs confirmed the presence of a face-centered cubic structure of crystalline AgNPs, while FTIR spectra showed the presence of biomolecules on their surface. …”