Empagliflozin Improves Insulin Sensitivity of the Hypothalamus in Humans With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial by Stephanie Kullmann (341793)

“…<p><b>Research Design and Methods:</b> In this randomized, double-blind, placebo-controlled clinical trial, 40 patients (mean ± SD; age: 60 ± 9 years; BMI: 31.5 ± 3.8 kg/m²) with prediabetes were randomized to receive 25 mg empagliflozin qd or placebo. …”

Presentation_1_Using Process Based Snow Modeling and Lidar to Predict the Effects of Forest Thinning on the Northern Sierra Nevada Snowpack.PDF by Sebastian A. Krogh (8601549)

“…At the 30-m forest stand scale, existing forest structure controls the efficacy of thinning, where forest stands with mean leaf area index (LAI) >3 m²/m² and 5–15-m tall show the largest increases in snow accumulation (up to 450 mm) and melt volume (up to 650 mm). …”

Image 4_Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study.tiff by Owen Griffith (20516501)

“…</p>Results<p>66 players were included (mean age 20.6 years; 100% male; 34 (51.5%) non-speed position players). …”

Image 2_Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study.tiff by Owen Griffith (20516501)

“…</p>Results<p>66 players were included (mean age 20.6 years; 100% male; 34 (51.5%) non-speed position players). …”

Viral Infection of Human Lung Macrophages Increases PDL1 Expression via IFNβ by Karl J. Staples (457228)

“…Knockdown of IFNβ by siRNA, resulted in a 37.5% reduction in IFNβ gene expression in response to infection, and a significant decrease in PDL1 mRNA. …”

Glibenclamide reduces the apoptosis and the loss of CVx36 in MIN6 cells exposed to Th1 cytokines. by Smaragda Lamprianou (3599570)

“…<p><b>a)</b> Apoptosis of MIN6 cells was evaluated by the proportion of Annexin V-stained cells (green) out of the total number of cells screened (identified by the blue DAPI staining of nuclei). …”

Abnormal Circadian Blood Pressure Variation is Associated with SYNTAX Scores in Hospitalized Patients with Acute Coronary Syndrome by Turhan Turan (13032107)

“…After the exclusion criteria, 141 patients (34 female and 107 male; mean age 61 ± 11 years) were included. Non-dipper hypertension has been defined as a 0% to 10% decrease in average systolic BP at nighttime compared to daytime, measured at hourly intervals using the same automatic BP measuring device on bedside monitors (Vismo PVM-2701; Nihon Kohden Corp., Tokyo, Japan). …”

Data_Sheet_1_Overall Dynamic Body Acceleration in Straw-Colored Fruit Bats Increases in Headwinds but Not With Airspeed.csv by M. Teague O'Mara (6760028)

“…There was a small, but negative, relationship between airspeed and ODBA, and bats decreased ODBA with increasing tailwind. Bats flew at ground speeds of 9.6 ± 2.4 ms⁻¹ (Mean ± SD, range: 4.3–23.9 ms⁻¹) and airspeeds of 10.2 ± 2.5 ms⁻¹, and did not modify their wingbeat frequency with speed. …”

Image_1_Treatment of Traumatic Intracranial Pseudoaneurysms: A Single-Center Experience.TIF by Yingwu Shi (9960683)

“…</p><p>Results: 20 patients were included in the present study with 17 males, and the mean of age on 27 years (IQR: 22, 44 years). Eight patients presented with epistaxis, followed by 5 patients with coma, 3 patients with visual defects and 2 patients with CSF leakage. …”

Data_Sheet_1_Deep Convolutional Neural Network Based Interictal-Preictal Electroencephalography Prediction: Application to Focal Cortical Dysplasia Type-II.docx by Yoon Gi Chung (9604061)

“…Intracranial EEG recordings of nine epilepsy patients with FCD type-II (four female, five male; mean age: 10.7 years) were analyzed. Seizure onset and channel ranking were annotated by two epileptologists. …”

DataSheet1_Intensive oral prophylaxis does not alter the tongue microbiome in young patients with chronic kidney disease: longitudinal, randomized, controlled study.pdf by Karolin C. Hoefer (19440076)

“…</p>Methods<p>Thirty patients with CKD (mean age 14.2 ± 5.2 years) and generalized gingivitis were included. …”

Allopregnanolone reduced expression of Aβ oligomers in 9- and 12-month-old male 3xTgAD mice. by Shuhua Chen (11649)

“…APα treatment significantly reduced Aβ 56 kD oligomer in the pre-pathology treatment (25±4%, <i>n</i> = 5, <i>P</i><0.01) and the post-pathology treatment (15±4%, <i>n</i> = 3–4, <i>P</i> = 0.05) groups. …”

Supplementary Material for: Early Physiological and Adrenal Effects of Budesonide Mixed with Surfactant in Large Observational Preterm Cohort Study by Becker S.A. (12572254)

“…<b><i>Background:</i></b> The combination of surfactant and budesonide has been shown to decrease BPD rates and severity. Budesonide may be released systemically from lungs, and the effects on the immature adrenal glands are not known. …”

Only Low Frequency Event-Related EEG Activity Is Compromised in Multiple Sclerosis: Insights from an Independent Component Clustering Analysis by Hanni Kiiski (133537)

“…Data were recorded from 128-scalp EEG channels and 4 IC clusters in the visual, and 5 IC clusters in the auditory, modality were identified. …”

Feeling the heat: Elevated temperature affects male display activity of a lekking grassland bird by Mishal Gudka (7387952)

“…<div><p>Most species-climate models relate range margins to long-term mean climate but lack mechanistic understanding of the ecological or demographic processes underlying the climate response. …”

Effects of p27^kip1 loss of function on MG activation in retinal explants. by Carolina Beltrame Del Debbio (243080)

“…<p><b>(A)</b> Adult rat retinal explants were transduced overnight with <i>p27</i>^<i>Kip1</i> shRNA or control lentivirus and cultured for 5 days in retinal culture medium. Immunohistochemical analysis of retinal explants revealed a decrease in immunoreactivities corresponding to p27^Kip1 in the p27^Kip1 LOF group. …”

Hypoglycemia caused a change in MDA-MB-231BR cell morphology. by Sirin A. I. Adham (662525)

“…There was a significant decrease in the reduced Alamarblue when the cells were grown in hypoglycemia for 24 hrs (MDA-MB-231P, MDA-MB-231BO, and MDA-MB-231BR) Results are shown as mean ± SD and were statistically analyzed by a two-tailed student’s t test (n = 3).…”

Table 1_Efficacy and safety of live combined Bacillus subtilis and Enterococcus faecium in patients with constipation: a meta-analysis of randomized controlled trials.docx by Wenwen Li (735004)

“…The experimental group showed a higher total effective rate [odds ratio (OR) (95% confidence interval (CI)) = 5.789 (4.598–7.288); p < 0.001], Bristol Stool Scale score [standardized mean difference (SMD) (95% CI) = 2.532 (1.274–3.790); p < 0.001], defecation frequency per week [SMD (95% CI) = 1.937 (1.252–2.623); p < 0.001], and defecation rate within 24 h [OR (95% CI) = 2.545 (1.377–4.705); p = 0.003] than the control group. …”

Data_Sheet_1_Acupuncture for insomnia symptoms in hypertensive patients: a systematic review and meta-analysis.DOCX by Jieying Zhang (4848082)

“…The evidence was synthesized by calculating the difference between mean differences (MD) in symptom change. The quality of the evidence was determined using the Cochrane Risk of Bias tool. …”

Table_3_High Betaine and Dynamic Increase of Betaine Levels Are Both Associated With Poor Prognosis of Patients With Pulmonary Hypertension.docx by Yicheng Yang (12319574)

“…The primary endpoint was defined as composite outcome events and the mean duration was 14.3 (6.9, 21.3) months. The associations of betaine and changes of betaine (Δbetaine) with disease severity and prognosis were explored.…”