Effect of the lytic enzyme PeiR on M1 growth <i>in vitro</i>. by Sinead C. Leahy (244590)

“…Addition of higher concentrations of PeiR (7.5 and 22.5 mg per litre) resulted in a lasting effect, with (A) no subsequent recovery of growth and (B) a reduced methane yield. …”

Reelin is secreted by GABAergic neurons. by Cecilia Gonzalez Campo (264260)

“…Values were 100.0±0.0% and 91.1±4.5% (n = 3 and 3) in BFA-treated conditions, 97.2±1.3% and 93.6±5.2% (n = 4 and 5) in vehicle conditions.…”

Quantifying the Human Cost of Global Warming (Code) by Timothy M. Lenton (15312245)

“…Reducing global warming from 2.7 to 1.5 °C results in a ~5-fold decrease in the population exposed to unprecedented heat (MAT ≥29 °C). …”

Arrangement of hop experimental plot and comparisons of the growth of infected plants. by Yoko Kawaguchi-Ito (255385)

“…Mean vine length was only 54% that of healthy controls even in the 2^nd season, and further decreased to less than half by the 5^th season. …”

<i>F. novicida</i> deletion mutants of a putative transglutaminase are severely attenuated in virulence and growth. by Madeleine G. Moule (243057)

“…The difference between the mean number of CFUs of wild-type and FTN_0869 has decreased at every timepoint, with only a 2.9-fold increase in wild-type bacteria compared to FTN_0869 bacteria at 24 hours, 6-fold more bacteria in U112 infected flies at 48 hours, and only 4-fold more U112 bacteria than FTN_0869 bacteria at 72 hours. …”

A Randomized, Placebo Controlled, Double Masked Phase IB Study Evaluating the Safety and Antiviral Activity of Aprepitant, a Neurokinin-1 Receptor Antagonist in HIV-1 Infected Adul... by Pablo Tebas (27720)

“…<div><h3>Background</h3><p>Neurokinin-1 receptor (NK1R) antagonists have anti-HIV activity in monocyte-derived macrophages, decrease CCR5 expression and improve natural killer cell function <em>ex vivo</em>. …”

Flow cytometric analysis of putative cancer stem cell pools in control and Syndecan-1-silenced MDA-MB-231 breast cancer cells. by Sherif A. Ibrahim (504852)

“…Syndecan-1 siRNA knockdown results in a significant decrease of the SP and ALDH activity. Data are expressed as mean percentage +/- SEM relative to the controls (set to 100%). …”

Down-regulation of the <i>cwp</i> genes in cells expressing the <i>luciferase</i> gene with a nonsense mutation. by Yi-Hsiu Chen (375991)

“…(B) Nonsense mutation leads to a decrease of luciferase activity. After stable transfection with the pPT5 and pPT5m constructs, luciferase activity was measured in vegetative cells. …”

IP3Rs localization and function. by Ilanit Itzhaki (225708)

“…(<b>E–F</b>) Dose-response curves displaying the effects of 2-APB (0.1, 0.5, 1, 2, 5 and 10 µM) (E) and U73122 (0.5, 1, 2 and 3 µM) (F) on whole-cell [Ca²⁺]_i transients amplitude (displayed as the relative decrease (%) versus baseline values). …”

Subcutaneous transplantation of L23 cells in the ear induce fast rejection and reduced proliferative response of draining lymph node cells. A: by Lilli Kraus (302769)

“…Lymphocytes were (re-)stimulated with 2×10³ irradiated L23 cells for 5 days. Comparison of proliferative response showed a decrease of ³H thymidin incorporation in draining lymph nodes. …”

Assessment of oscillatory potential (OP) amplitude profiles. by Jake Bedore (777372)

“…Quantification of summed OP amplitude for the four OPs measured over the four largest stimulus strengths (0.63–25 cd˖s /m²) under scotopic conditions measured shows a significant decrease in VAChT^{Six3-Cre-flox/flox} retinas (open circles) relative to littermate controls (VAChT^flox/flox, closed squares) at (I) 5 (n = 7 VAChT^{Six3-Cre-flox/flox} and n = 12 littermate control) and (J) 12 months of age (n = 5 VAChT^{Six3-Cre-flox/flox} and n = 5 littermate control). …”

Involvement of calcium influx and intracellular stores in NH₄⁺/NH₃-induced calcium changes. by Nicole Haack (621328)

“…<b>(A)</b>, <b>(B)</b> The grey bars indicate the average amplitude of the sustained calcium increase evoked under control conditions in the absence of blockers (∼50 nM) <b>(C)</b> Histogram showing the mean peak amplitude ± S. E. M. of sustained calcium changes in response to NH₄⁺/NH₃ in the control, in the nominal absence of extracellular calcium, in the absence of extracellular calcium combined DLAP5, in the presence of CPA and in the combined presence of CPA and DLAP5. …”

Effects of site-specific sustained photostimulation of inhibitory neurons within the pre-Bötzinger complex <i>in situ</i>. by Jessica Ausborn (5147210)

“…(<b>D</b>) Summary data (n = 10, mean ± SEM, **p<0.01, *p<0.05) of bilateral pre-BötC photostimulation shows that relatively weak (0.5–2.0 mW) stimulation significantly increased respiratory frequency in a laser power-dependent manner, and stronger (4.0–5.0 mW) stimulation caused a decrease of inspiratory frequency with complete termination of inspiratory activity for the stimulus duration at the maximum laser power (5.0 mW).…”

LPO substrate specificity and susceptibility map of influenza strains. by Urmi Patel (5558513)

“…The X axis shows susceptibility against OSCN^- while the Y axis shows susceptibility towards OI^-. Mean+/-S.E.M. for both, X and Y axes, n = 2–5. The indicated diagonal crossing on the map from the lower left corner to the upper right corner indicates no substrate preference, irrespective of susceptibility. …”

Effect of convergence criterion on overall solution accuracy. by Christian Schlinkmann (9585315)

“…At 6% error a value of 1.0×10⁻⁵ already gives a good approximation of the final solution, with the overall error stabilizing at 3.7% for a value of 1.0×10⁻⁷. b) Mean relative error of the displacements as a function of simulation time, using no additional levels of detail and 1.0×10⁻⁷ as convergence criterion. c) Relative error of the maximum displacement in an analytical example consisting of a steel beam with a compressive load applied parallel to the longest axis. …”

Quantification of ICAM-1 adhesion. by Jaap D. van Buul (5650009)

“…Experiment is done three times in duplicate. Data are mean ± SEM. *p<0.01.</p>…”

Strong interdependence generates communities that are robust to variation in initial conditions. by Sylvie Estrela (156401)

“…An increment in initial segregation of 0.1 means a 5% increase (or decrease) in the number of cells of species A (or species B) inoculated in each microcolony. …”

DP-b99 diminishes neurodegenerative effect of kainate in hippocampal slice cultures. by Marine Yeghiazaryan (576485)

“…<p><b>A</b> – Representative fluorescence photomicrographs of organotypic hippocampal slices (16 DIV) showing uptake of PI 24 h after various treatments: CTRL (untreated cultures); DP-b99 20 µM and 0.12 µM; KA (5 µM); KA+DP-b99 20 µM or 0.12 µM. <b>B -</b> Quantification done by ImageJ software and represented in arbitrary units of fluorescence shows a significant decrease in neuronal death in all groups treated with DP-b99 (n = 3, mean ± SE; * - p<0.05). …”

Proliferation of HBO-treated cells. by Jennifer Schulze (2502799)

“…Both NIH3T3 and NIH3T3/BDNF fibroblasts show a highly significantly increased cell number compared to the control cells (normoxic and normobaric conditions (NOR), green inverted triangle and line) after five consecutive HBO treatments. By contrast, the proliferation of MSCs started to decrease after five consecutive HBO treatments with 2.0 bar until the end of ten treatments in comparison to NOR. …”

Oligodendrocyte depletion with DT results in axonal damage but does not affect cortical neuronal density. by Aniket Ghosh (212168)

“…Quantifications represent mean and SEM (n = 8 MOGi-Cre/iDTR mice treated with DT, 5 DT-treated MOGi-Cre animals as control (middle panel) and 3 MOGi-Cre/iDTR animals treated with PBS, ns: not significant).…”