Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Effect of Molecular Structure on the B3LYP-Computed HOMO–LUMO Gap: A Structure −Property Relationship Using Atomic Signatures by Ahmed Mohamed (628889)

“…The atomic fragments containing π-bonds in various aromatic compounds were found to be the most significant atomic Signatures, explaining nearly 50% of the variance in the data, with regression coefficients that decreased <i>E</i>_gap. …”

Assessment of indicators of vitamin A status in non-cirrhotic chronic hepatitis C patients by R.C. Santana (6516497)

Contrast sensitivity is transiently reduced at 5 hr post-sildenafil. by Bruce A. Berkowitz (8282913)

“…<p>Compared to uninjected 5 hr light adapted mice (white bar), sildenafil + saline (green bars) A) decreased contrast sensitivity only under SDL conditions but B) did not change spatial frequency threshold (SFT). …”

Supplementary Material for: Association of platelet count and mean platelet volume with fish intake frequency: Implication for the cardioprotective effect of fish intake by figshare admin karger (2628495)

“…Introduction: Mean platelet volume (MPV) measures platelet activity, and high values indicate increased atherosclerotic cardiovascular disease (ASCVD) risk. …”

IFA disarmed capsule-mediated immune evasion. by Tingting Wang (123983)

pI7L suppresses the IFN-γ-triggered JAK-STAT signaling pathway. by Meilin Li (1832905)

Reduction of L O-ag production and antigenic shift to O2-antigen in by Fermin E. Guerra (6084545)

“…<p><b><i>S.</i> Paratyphi A decreases IgM binding. (</b>A) and (B) Restored <i>S.…”

Trust levels before and after the COVID-19 pandemic (n = 10,000). by Alain Abi-Rizk (8549358)

Effect of RYGB on distribution of GLP-2 positive cells. by Ananyaa Sridhar (13844261)

Effect of RYGB on distribution of PYY positive cells. by Ananyaa Sridhar (13844261)

Effect of RYGB on distribution of GIP positive cells. by Ananyaa Sridhar (13844261)

Effect of RYGB on distribution of GLP-1 positive cells. by Ananyaa Sridhar (13844261)

The technical route of the study. by Hongliang Zou (20707270)

“…The highest root-mean-square error recorded was 2.72m in five sequences from a multi-modal multi-scene ground robot dataset, which was significantly lower than competing approaches. …”

Point cloud fusion instance effect. by Hongliang Zou (20707270)

“…The highest root-mean-square error recorded was 2.72m in five sequences from a multi-modal multi-scene ground robot dataset, which was significantly lower than competing approaches. …”

Experimental results in the SubT-MRS dataset. by Hongliang Zou (20707270)

“…The highest root-mean-square error recorded was 2.72m in five sequences from a multi-modal multi-scene ground robot dataset, which was significantly lower than competing approaches. …”

Gating properties of <i>CACNA1I</i> variants with pooled WT data. by Yousra El Ghaleb (22075892)

The mean annual TSS and TN load and concentration and area normalized (AN) load at the watershed outlet for the BASE20 and future scenarios. AN load includes the contribution of po... by Elly T. Gay (21170097)

Table 1_Trends and forecasts of vitamin A deficiency burden in China, 1990–2035.docx by Zhongming Ye (21865547)

“…However, DALYs rebounded among those aged 50–74 years. Significant age and sex disparities exist. …”