Quantitative prediction of beneficial heteroplasmy variance generated by different cellular mechanisms. by David M. Edwards (10692265)

Loss of <i>FGR41</i> modestly delays hyphal development <i>in vitro</i>. by Andrew S. Wagner (11331477)

Synthetic Spike-in Standards Improve Run-Specific Systematic Error Analysis for DNA and RNA Sequencing by Justin M. Zook (146772)

“…Compared to conventional GATK recalibration that uses reads mapped to the genome, spike-ins improve the accuracy of Illumina base quality scores by a mean of 5 Phred-scaled quality score units, and by as much as 13 units at CpG sites. …”

Data_Sheet_1_Platelet Measurements and Type 2 Diabetes: Investigations in Two Population-Based Cohorts.docx by Benjamin A. T. Rodriguez (9107027)

“…Interestingly, sex-stratified analyses indicated the association of MPV with diabetes is markedly stronger in males (β = 0.1232; P = 1.00 × 10⁻³¹) than females (β = 0.0514; P = 7.37 × 10⁻⁵). Among diabetes medications increased MPV was associated with Insulin (β = 0.1341; P = 1.38 × 10⁻¹¹) and decreased MPV with both Metformin (β = 0.0763; P = 1.99 × 10⁻⁶) as well as the sulphonylureas (β = 0.0559; P = 0.0034). …”

Linear mixed model results: Effect of bar height and approach stride number on kinetics at take-off to a jump in agility dogs. by Leena Inkilä (20614460)

Protein expression analysis. by Archana Pandita (627056)

Attenuation of Quorum Sensing Regulated Virulence of <i>Pectobacterium carotovorum</i> subsp. <i>carotovorum</i> through an AHL Lactonase Produced by <i>Lysinibacillus</i> sp. Gs50 by Sneha S. Garge (3375242)

“…Our results demonstrate the potential of <i>Lysinibacillus</i> sp. Gs50 as a preventive and curative biocontrol agent.…”

Quality of life and Beck Depression Inventory baseline and post CRT+MRT, CRT and RUHB. by Sergio R. Thomaz (20308465)

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Cardiorespiratory variable measurement of the study population. by Sergio R. Thomaz (20308465)

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ΔQuality of life and ΔBeck Depression Inventory baseline and post CRT+MRT, CRT and RUHB. by Sergio R. Thomaz (20308465)

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Changes in maximal strength within each group after treatment. by Sergio R. Thomaz (20308465)

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ΔVO₂ (ml/min), ΔVO₂/HR and ΔVE/VCO₂ slope baseline and post CRT+MRT, CRT and RUHB. by Sergio R. Thomaz (20308465)

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Role of the ACB domain and linker region in NMT2 activity. by Eric Soupene (64584)

“…Human NMT2 enzyme was added at a concentration of 50nM in the presence of 5μM C₁₄-CoA. …”

Pre-diabetes is associated with increased risk of heart failure among patients with atrial fibrillation by Jia-Yi Huang (12733928)

“…</p> <p><strong>Results</strong>: Among 17,943 AF patients (mean age 75.5 years, 47% female), 3,711 (20.7%) had pre-diabetes and 10,127 (56.4%) had diabetes at baseline. …”

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

Knockdown of IFI27 impairs LCL survival <i>in vitro</i> and <i>in vivo</i>. by Ken Sagou (1945318)

Disruption of the viral cyclin has no effect on the frequency of viral genome positive cells yet results in a reduced frequency of LANA::βla+ cells. by Brian F. Niemeyer (11707995)

High-dose thiamine prevents brain lesions and prolongs survival of <i>Slc19a3</i>-deficient mice by Kaoru Suzuki (4217638)

“…To investigate the molecular mechanisms of neurodegeneration in SLC19A3 deficiency and whether administration of high-dose thiamine prevents neurodegeneration, we generated homozygous Slc19a3 E314Q knock-in (KI) mice harboring the mutation corresponding to the human SLC19A3 E320Q, which is associated with the severe form of THMD2. …”

Normalized diatom species abundance for all species (A) and mean Fisher Information (B) for Foy Lake. by Trisha L. Spanbauer (639221)

“…At ∼4.5 ka species evenness decreases, and the system begins a ∼2 kyr gradual decrease in mean FI. …”

PRMT5 regulates EMT and invasion under hypoxia. by Srinivas Abhishek Mutnuru (22513457)

“…<b>C)</b> Immunoblot showing decrease in histone marks HR38me2s and H4R3me2s upon vehicle (DMSO) vs. 5 µM GSK591 treatment in MCF7 cells under hypoxia. …”