Data Sheet 1_Global assessment of terrestrial precipitation and evapotranspiration in CMIP6 simulations using observation-based estimates.docx by Shanshan Sun (275585)

“…We assess these variables using observation-based estimates from three Pr datasets (CRU4.0, GPCP v2.3, ERA5) and four land surface flux datasets (GLEAM v3.3a, GLDAS v2.0, ERA5-Land, MERRA-Land). …”

Image_2_A Phase 1 Dose-Escalation Study of PF-06671008, a Bispecific T-Cell-Engaging Therapy Targeting P-Cadherin in Patients With Advanced Solid Tumors.tif by James J. Harding (12415627)

“…Adult patients with treatment-refractory solid tumors received PF-06671008 (1.5–400 ng/kg) as a weekly intravenous (IV) infusion on a 21-day/3-week cycle. …”

Variations of <em>CHI3L1</em>, Levels of the Encoded Glycoprotein YKL-40 and Prediction of Fatal and Non-fatal Ischemic Stroke by Camilla Noelle Rathcke (139771)

“…Both continuous YKL-40 levels and 4^th quartile YKL-40 values (>85 ng/ml) were associated with all-cause mortality (HRs 1.22 (95% CI, 1.10–1.35), p<0.0001, and 1.40 (1.15–1.71), p<0.0001), an increased risk of first-time stroke (HR 1.16 (1.01–1.33), p = 0.04, and 1.63 (1.23–2.16), p = 0.001) and a decreased risk of incidence of IHD (HR 0.77 (0.65–0.91), p = 0.002, and 0.61 (0.44–0.85), p = 0.003).…”

Nanoliter-Scale Droplet–Droplet Microfluidic Microextraction Coupled with MALDI-TOF Mass Spectrometry for Metabolite Analysis of Cell Droplets by Wen-Hua Sun (1392202)

“…A linear relationship (<i>y</i> = 0.0305<i>x</i> + 0.376, <i>R</i>² = 0.984) was obtained in the range of 4–100 ng/mL, with the limits of detection and quantitation being 2.2 and 4.5 ng/mL for SN-38, respectively.…”

Data_Sheet_1_Dynamic Changes of Endogenic or Exogenic β-Carboline Alkaloid Harmine in Different Mammals and Human in vivo at Developmental and Physiological States.pdf by Ning Cao (158319)

“…The concentration of harmine in rat plasma showed a decreasing trend similar to the exposure levels of neurotransmitters such as 5-hydroxytryptamine, acetylcholine chloride, glutamic acid, tyrosine, and phenylalanine during the growth period of 18 months. …”

Table_1_Mucopolysaccharidosis Type IVA: Extracellular Matrix Biomarkers in Cardiovascular Disease.pdf by Brittany Montavon (12520978)

“…Plasma/urine keratan sulfate (KS), and urinary glycosaminoglycan (GAG) levels were significantly higher in Morquio A patients (p < 0.001) which decreased with age of patients. CTSS levels did not correlate with patients’ phenotypic severity but differed significantly between patients (median range 5.45–8.52 ng/mL) and normal controls (median range 9.61–15.9 ng/mL; p < 0.001). …”

Data Sheet 1_Associations of per- and polyfluoroalkyl substances in follicular fluid with polycystic ovarian syndrome in infertile women may be mediated by sex hormones.docx by Zhizhen Pan (13104271)

“…</p>Results<p>The study showed that perfluoro-n-octanoic acid (PFOA) and potassium perfluoro-1-octanesulfonate (PFOS) were the dominant PFAS in the follicular fluid samples, with the median concentration of 4.35 ng/mL and 5.22 ng/mL, respectively. Perfluoro-n-hexanoic acid (PFHxA) were correlated with increased incidences of PCOS (medium vs. low tertile: OR = 1.78, 95% CI: 0.18, 17.19). …”

Data_Sheet_1_Associations of Serum Uromodulin and Its Genetic Variants With Blood Pressure and Hypertension in Chinese Adults.docx by Yang Wang (5921)

“…Furthermore, serum uromodulin levels in the hypertensive subjects were lower than in the normotensive subjects (25.5 ± 1.1 vs. 34.7 ± 0.7 ng/mL). Serum uromodulin levels decreased gradually as BP levels increased (34.6, 33.2, 27.8, and 25.0 ng/mL for subjects with normotension, high-normal, grade 1 hypertension, and grade 2 hypertension, respectively). …”

Image_1_A Phase 1 Dose-Escalation Study of PF-06671008, a Bispecific T-Cell-Engaging Therapy Targeting P-Cadherin in Patients With Advanced Solid Tumors.tif by James J. Harding (12415627)

“…Adult patients with treatment-refractory solid tumors received PF-06671008 (1.5–400 ng/kg) as a weekly intravenous (IV) infusion on a 21-day/3-week cycle. …”

Rearrangement of actin cytoskeleton in treated and untreated MDA-MB 435 breast cancer cells by Robert F. Klees (62686)

“…</p><p></p> Cells were plated on fibronectin for 4 hours in the presence of either compound 9 (panel (c)), compound A5 (panel (d)), or compound A8 (panel (e)) at a final concentration of 15.2 ng/μl and were compared to the positive control (panel (a)) and the ethanol vehicle (panel (b)).Cells were fixed and stained for F-actin using TRITC-phalloidin. …”

Tfh cells from HCC patients suppress the maturation of autologous B cells. by Yiqiong Jia (692871)

“…<p>(A) Circulating CXCR5+CD4+ Tfh cells from HCC patients (pTfh) or healthy controls (hTfh) and allogeneic CD19+ B cells from healthy controls (hB) are incubated at a ratio of 1:1 in the presence of SEB (100 ng/ml) in RPMI1640 complete medium; after 7–8 days of culture, the B cell subpopulations are examined by the surface phenotype. …”

Validation of primers via conventional PCRs. by Zhengqing Wan (8556198)

“…<p>(A, B, C) Conventional PCR amplification with 1 pg of HCF DNA as template in the background of 100 ng of human genomic DNA with each primer pair. Expected products were observed with the primer pairs Egs-1, Egs-2, Egs-3, mgs-1, mgs-4, mgs-5, mgs-6, mgs-7, mgs-9, mgs-10, mgs-12 and mgs-14. …”

The Effect of PLGA Conduit Loading Insulin-like Growth Factor 1 Modified by Collagen-Binding Domain on Peripheral Nerve Injury of Rats. by Jian`an Li (5221370)

“…Compared with the absorbance of 125ng / ml drug solution, there is a burst release of 82% (IGF-1) and 8% (CBD-IGF-1) of the total growth factors released from the PLGA/col conduits within 12 hours. …”

Results of the metabolomics analysis. by Guang-ping Ruan (3955208)

“…In the positive ion mode, the levels of three substances were significantly decreased in the induced cell treatment group compared with the model control group (mean±standard deviation, n = 5). * indicates p = 0.041 compared with the model group.…”

Increased susceptibility to DSS-induced colitis in <i>Oasis</i>−/− mice. by Kenta Hino (519150)

“…(F) HE (upper panels) and PAS (lower panels) staining of large intestines from WT and <i>Oasis</i>−/− mice exposed to 3.5% DSS for 5 days. Note that the <i>Oasis</i>−/− large intestine exhibited mucosal damage, degeneration of the mucosal epithelium, a decrease in the number of goblet cells, and an increase of crypt loss compared with those in WT large intestines. …”

Depleted pool of oNSCs and diminished neurogenesis in embryonic <i>BAF155</i>cKO OE. by Christina Bachmann (3111933)

“…(G–L) Statistical quantification of panels A–F is shown. Note the decrease in the number of Sox2⁺ oNSCs at both E10 and E13.5. …”

Downregulation of different classes of genes in cutaneous SCC cells by KGF as determined by DNA microarray analysis. by Mervi Toriseva (145888)

“…<p>Three KGFR-positive SCC cell lines were serum-starved and treated with rKGF (10 ng/ml) for 24 h. Total RNA was analyzed for differential gene expression by Affymetrix microarray. …”

Influences of Excluded Volume of Molecules on Signaling Processes on the Biomembrane by Masashi Fujii (409503)

Table_1_Delayed Initiation of ECMO Is Associated With Poor Outcomes in Patients With Severe COVID-19: A Multicenter Retrospective Cohort Study.DOCX by Xuyan Li (829442)

“…Early initiation of ECMO was associated with decreased 60-day mortality after ECMO (50 vs. 88%, P = 0.044) and an increased ECMO weaning rate (50 vs. 6%, P = 0.011).…”

Role of miR-150 in the effect of adenosine on CXCR4. by Magali Rolland-Turner (290098)

“…Ado increased CXCR4 expression (A) and decreased miR-150 expression (B). * P<0.05 vs control (n = 5). …”