Mapping changes in patterning after inhibition of Notch activity. by Matthew French (13007466)

“…Note the statistically significant decrease in the CLE and NSB like regions TBX6. Data for Fig 7 (D–F): Data file 3, <a href="https://doi.org/10.5281/zenodo.15802710" target="_blank">https://doi.org/10.5281/zenodo.15802710</a>.…”

Inhibition controls levels of pattern separation in granule cells through different neural codes. by Antoine D. Madar (6619286)

“…<p><b>(A)</b> Single GCs were recorded twice in response to the same input set (P10Hz, R = 0.76 at τ_w = 10 ms, shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006932#pcbi.1006932.g001" target="_blank">Fig 1B</a>): First in normal aCSF, then under conditions of partial inhibitory block (aCSF + 100 nM gabazine, gzn), without changing any other parameter (i.e. same stimulation location and intensity). …”

MAGLi 432 treatment after LPS challenge does not reduce BBB permeability and inflammatory cytokine expression in the cortex. by Alicia M. Kemble (8555517)

“…<p><b>(A)</b> Immunofluorescence micrographs of 100-μm cortical sections from mice (n = 6) injected with 70-kDa FITC-dextran following LPS challenge and treatment (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0268590#pone.0268590.g003" target="_blank">Fig 3A</a></b>) stained with an anti-CD31 (PECAM-1) antibody (orange) to label blood vessels and DAPI as a nuclear stain (blue). …”

Burst stimulation. by Damian M. Herz (16007088)

“…In all patients, DBS was given in bursts of varying duration (mean 250 ms). Between stimulation bursts was an approximately 500-ms long pause (mean 150 ms interval + ramping up and down each lasting ca. 175 ms on average = 500 ms, see also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002140#pbio.3002140.s008" target="_blank">S1 Table</a>). …”

Effect of pazopanib on primary tumor growth of breast cancer and melanoma cell lines. by Brunilde Gril (202357)

“…P values are shown for the tumors in which the decrease in tumor size achieved significance (p<0.01) at a given dose of pazopanib. …”

Infectivity of <i>LdASS</i> mutants in the murine model. by Abul Hasan Sardar (573177)

“…In the <i>LdASS</i>^-/-/+ parasites, the IL-12 and IFN-γ were increased whereas IL-10 and TGF-β were decreased compared to WT parasites. Each measurement was performed in triplicate and data are expressed as the mean. …”

Effect of conversion from calcineurin inhibitors to everolimus on hepatitis C viremia in adult kidney transplant recipients by Larissa Sgaria Pacheco (5221397)

“…The mean eGFR was similar in both groups. Conclusion: Our study did not show viral load decrease after conversion to EVR with maintenance of antiproliferative therapy.…”

Effect of conversion from calcineurin inhibitors to everolimus on hepatitis C viremia in adult kidney transplant recipients by Larissa Sgaria Pacheco (5221397)

“…The mean eGFR was similar in both groups. Conclusion: Our study did not show viral load decrease after conversion to EVR with maintenance of antiproliferative therapy.…”

Impact of community mask adherence and attitudes. by Dhaval Adjodah (11014160)

“…<p>Using a novel survey-based dataset of 847 thousand online Facebook survey respondents in 51 languages from 69 countries, we estimate that a 1% increase in community mask adherence is associated with a decrease of -0.61 [-0.82,-0.39] cases per 100K and a decrease of -0.035 [-0.040,-0.029] deaths per 100K. …”

HDAC inhibition blocks Glyc-Alb induced activation of HDACs. by Danielle Desjardins (735474)

“…<p>(A) ARPE19 cells showed a significant decrease in Ac-α-tubulin at 6 h post treatment of Glyc-alb (100 μg/mL) compared to administration of the same concentration of Alb. …”

Biochemical analysis of manganese-induced changes in the tissue level of monoamines. by Safa Bouabid (572715)

“…<p>Manganese-induced a decrease in the tissue level of NE and 5-HT in the frontal cortex and increase of DA metabolism in the striatum. …”

Collective behavior in experimental data for validating model. by Giovanna De Palo (476510)

“…Note that the height of peaks increases and that the corresponding rescaled NN distance decreases with the number of cells, as it does for simulations. …”

Assessment of cell viability using quantification of lactate dehydrogenase (LDH) released by lesioned retinas treated with GJ blockers and openers. by Vera Paschon (306542)

“…On the other hand, we observed changes in LDH release when retinas were treated with the same drugs with a higher concentration (100 µM). (E) After incubating with CBX 100 µM for 4 h, we detected a significant decrease in the LDH release (−22%, <i>P</i><0.01). …”

Development and validation of liquid chromatography-tandem mass spectrometry method to quantify dasatinib in plasma and its application to a pharmacokinetic study by Edlaine Rijo Costa (5153600)

“…Cmax = 164.5 ng/mL. The described analytical method was successfully employed in pharmacokinetic study of DAS in mice.…”

Bcl-xL regulation of NF-κB RNAs: by Chi Zhang (9857)

“…<p>A: RNA was extracted from eggs and embryos at various stages and analyzed by RT-PCR (28 cycles); levels of RelA, Rel2, Rel3, RelB and Xp100 RNAs drop between stage 7 and 9 and, except for RelB, increase following gastrulation (stage 12/13). …”

FCF affects HIF-1α expression on the posttranslational level. by Dikla Vardi-Oknin (447319)

“…Quantitative real-time PCR analysis was done using primers for HIF-1α and cyclophilin B as control<i>. Columns</i>, means (n = 2); <i>bars</i>, SD. (<b>B</b>) PC-3 cells were treated with vehicle (control) and 100 μM FCF for 4 h under normoxia, and then CHX was added at a final concentration of 10 μg/ml for the indicated times. …”

The inhibition of mitochondrial respiratory chain complex activity by longer chain TPP⁺ compounds is dose dependent. by Jan Trnka (441288)

“…<p>Samples of rat skeletal muscle homogenate were incubated with various concentrations of decylTPP⁺ and dodecylTPP⁺ prior to the assay. <b>A, B, and C.</b> Complexes I, II, and III show a gradual decrease in activity proportionate with the dose of the TPP⁺ compounds. …”

<i>Mll2^Gdf9</i> cKO oocytes show loss of bulk H3K4me2 and H3K4me3 as well as H4 hyperacetylation. by Claudia V. Andreu-Vieyra (243666)

“…In contrast, a decrease in H3K4me2 (B) and H3K4me3 (C) levels was observed in <i>Mll2^Gdf9</i> cKO oocytes (B and C, lower panels) compared to controls (B and C, upper panels). …”

Supplementary Material for: Carpal Tunnel Surgery as Proxy for Dialysis-Related Amyloidosis: Results from the Japanese Society for Dialysis Therapy by Hoshino J. (4145806)

“…<b><i>Methods:</i></b> The cohort consisted of 166,237 patients on dialysis (mean age 66.1 ± 12.4 years; mean dialysis vintage 7.2 ± 6.4 years) who could be followed for a year between 2010 and 2011. …”

TGF-β₁ mediated changes in primary human osteoblasts are Smad2/3-dependent. by Sabrina Ehnert (359631)

“…<p>(A) Primary human osteoblasts (N = 4, n = 3) infected with Ad5-CAGA₉-MLP-Luc reporter constructs (Smad2/4 reporter) were stimulated with 5 ng/ml hra TGF-β₁ in the presence or absence of the Alk5 inhibitor SB431542 (5, 10, 20 and 40 nM). …”