RANKL and RANK Protects Mouse Podocytes from Apoptosis. by Shuangxin Liu (314178)

“…(J) Exogenous RANKL protected podocytes from PA induction apoptosis. RANKL (40 ng/ml) decreased PA-induced apoptosis (15.5±2.2%). …”

DataSheet_1_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.docx by Jacob MacWilliams (5040044)

“…This suggests that other cannabinoids and/or metabolites such as terpenes are causing the observed decrease in aphid performance in the whole plant assays. …”

Image_1_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.jpeg by Jacob MacWilliams (5040044)

“…This suggests that other cannabinoids and/or metabolites such as terpenes are causing the observed decrease in aphid performance in the whole plant assays. …”

Image_2_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.jpeg by Jacob MacWilliams (5040044)

“…This suggests that other cannabinoids and/or metabolites such as terpenes are causing the observed decrease in aphid performance in the whole plant assays. …”

Regulation of HBV replication by agarose gel analysis in cells treated with miRNA. by Sun O. Park (319202)

“…<p>For these studies, 2.2.15 cells were transfected with miRNA mimics or miRNA antagonists followed by administration to transduced cells of either 20 ng/ml TGF-β or 100 µM iron for 48 h. (A) Changes in iron-treated cells are shown after expression of miR-125a-5p or -151-5p mimics. …”

Cell death delay sensitivity to the change in ProCasp6 concentration and Casp3 degradation kinetics in the clustering scenario. by Anna Matveeva (7430492)

“…<p>(A) Dramatic increase in the cell death delay upon the increased Casp3 degradation rate constant (kcat) by XIAP mediated ubiquitination which is a function of proteasomal protein degradation capacity as well as Casp3 self-cleavage for the cells stimulated with lower DL doses (5, 7.5 ng/mL). (B) High sensitivity to the minor decrease in XIAP concentration from its mean estimated concentration in HeLa cell 63 nM will lead to dramatic decrease in cell death delay for the cells stimulated with lower DL doses.…”

Characterization of the hESC differentiation model. by Sri Kripa Balakrishnan (71670)

“…<p>A. 10X Phase contrast images of H9 pluripotent hESCs and H9 hESCs induced to differentiate with BMP4 for 5 days. 200 ng/ml BMP4 in TeSR was used in all panels. …”

Results of morpholino knockdown and RNA rescue experiments by Brian E. Walter (47936)

“…Note the smaller size of the eye and severe reduction in the ventral region of the optic cup, denoted by the arrow in . : The corresponding fluorescence image shows the distribution of the lissamine-tagged morpholino for the embryo shown in . -: The typical result is observed following the co-injection of 4.5 ng morpholino and 1000 pg synthetic altPsf2 RNA. : The normal control, uninjected side of the embryo shown in - is displayed. : Normal morphological development is observed following the co-injection of Psf2MO (equivalent to 4.5 ng/blastomere at the eight-cell stage) and 1000 pg rescue RNA (altPsf2 RNA). : The corresponding fluorescence image to that shown in shows the distribution of the lissamine-tagged morpholino. -: Typical severe eye defect is observed following unilateral injection of lissamine-tagged Psf2MO into single blastomeres at the two-cell and four-cell stages (equivalent to 6 ng/blastomere at the eight-cell stage). : The normal control, uninjected side of the embryo shown in and is shown. : The typical severe eye defect phenotype is displayed following Psf2MO injection. …”

Data_Sheet_1_Elevated concentrations of macrophage migration inhibitory factor in serum and cerebral microdialysate are associated with delayed cerebral ischemia after aneurysmal s... by Felix Neumaier (4391794)

“…Subgroup analyses revealed significantly higher serum levels in patients with aneurysms located in the anterior vs. posterior circulation during CP_d5−15 (17.3 [15.1–21.1] vs. 10.0 [8.4–11.5] ng/ml, p = 0.009) and in patients with DCI vs. no DCI during CP_d5−15 (17.9 [15.1–22.7] vs. 11.9 [8.9–15.9] ng/ml, p = 0.026) and LP_d16−21 (17.4 [11.7–27.9] vs. 11.3 [9.2–12.2] ng/ml, p = 0.021). …”

Data_Sheet_1_Low-Dose Vitamin D Protects Hyperoxia-Induced Bronchopulmonary Dysplasia by Inhibiting Neutrophil Extracellular Traps.xlsx by Cuie Chen (2372758)

“…</p><p>Methods: Newborn rats were exposed to 90% oxygen continuously for 7 days to mimic BPD, and rats under hyperoxia were injected with 1,25(OH)2D3 at different doses (0.5 ng/g, 3 ng/g). Alveolarization, pulmonary vascular development, inflammatory cytokines and NETs were assessed.…”

Effect of inhibitors of p38 MAPK or PKC on stimulated shedding by ADAM17T735A and ADAM17ΔC. by Katherine C. Hall (180988)

“…C) <i>Adam17−/−</i> mEFs transfected with TGFα together with WT ADAM17 were stimulated with 5 ng/ml IL-1β, 1 µM anisomycin or 25 ng/ml PMA in the presence or absence of 4 µM BIM I. …”

Real-Time Cytotoxicity Assay for Rapid and Sensitive Detection of Ricin from Complex Matrices by Diana Pauly (170378)

“…For ricin, tested in concentrations of 0.06 ng/mL or above, a concentration-dependent decrease of cell index correlating with cytotoxicity was recorded between 3.5 h and 60 h. …”

Characterization of Tzb-refractory <i>HER2</i>-gene Amplified SKBR3 Breast Cancer Cells. by Alejandro Vazquez-Martin (75018)

“…Treatment with Tzb concentrations as high as 100 µg/mL Tzb failed to significantly decrease cell viability in TzbR POOLs whereas a 10 times lower concentration of Tzb drastically reduced cell viability (>50%) in SKBR3 parental cells. …”

Protein expression in response to insulin in palmitate treated myotubes from premenopausal and postmenopausal women. by Julie Abildgaard (593720)

“…Furthermore, one day of palmitate treatment led to a significant decrease in insulin stimulated phosphorylation of Akt in the myotubes from all the women, (C) Palmitate treatment decreased insulin stimulated p-AS160-Thr642 (160 kDa) in both pre-myotubes and post-myotubes. …”

DEP dissociate VEGF-R2 from adherens junction connection. by Chia-Yi Tseng (765451)

“…<p>(A) After 24 h DEP (1, 10 and 100 g/mL) exposure, the tube cells were lysed and harvested. …”

Q₁₀ values for resting oxygen consumption for the scincid lizards <i>Plestiodon fasciatus</i>, <i>Plestiodon inexpectatus</i>, and <i>Plestiodon laticeps</i>. by Charles M. Watson (2943942)

PaCDase and S1P activate NF-κB-dependent signal pathway. by Ami Oizumi (527413)

“…<p>(<i>A</i>) PaCDase and S1P significantly increase phosphorylated NF-κB p65 levels. …”

DataSheet1.docx by Katie M. O'Brien (250889)

“…The top hit was rs4588, a missense GC polymorphism associated with a 3.5 ng/mL decrease in 25(OH)D per copy of the minor allele (95% confidence interval [CI]: −4.1, −3.0; p = 4.5 × 10⁻³⁸). …”

Involvement of NO, prostacyclin and EDHFs on abacavir-induced relaxation of rat basilar arteries. by Rachel Wai Sum Li (422494)

“…Abacavir-induced relaxation of basilar arteries was then measured. (A) Changes in tension were expressed as the percentage decrease in response to contraction caused by endothelin-1 (ET-1; 1–10 nM). …”

Gradual increase in the extent of γ-secretase saturation with its substrate leads to gradual changes from the biphasic to the standard dose-response curves. by Željko M. Svedružić (105215)

“…Further increase in the substrate (i.e. cDNAwtC99 >250 ng/mL) leads to decrease in Aβ 1–40 secretion (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050759#pone-0050759-t002" target="_blank">Table 2B</a>), which indicates that the substrate can also bind to the inhibition site (i.e. antagonism between complex <b><u>5</u></b> and complex <b><u>6</u></b>).…”