<i>vang-1(tm1422)</i> life span modulation depends on Insulin/IGF-1-like signaling and leads to higher DAF-16 activity. by Sebastian J. Honnen (183696)

“…In contrast, depletion of DAF-16 by RNAi in <i>tm1422</i> (rose spotted line) and WT (purple solid line) causes a decrease of mean life span to <b>12±0.3 d</b> (n = 247*) and <b>11.9±0.2 d</b> (n = 142*), respectively (p<0.96**). …”

Lovastatin in combination with VEGFR-2 TKIs inhibits ligand induced activation of AKT, S6K1 and 4EBP1. by Tong T. Zhao (361937)

“…<p>Control cells were serum starved for 24 hr followed by 2 hr treatments with either 10 µM KRN633, 10 nM rapamycin, 5 µM lovastatin or their combinations. All cells were then lysed after stimulation with 50 ng/ml VEGF₁₆₅ for 30 min. …”

Controlling the G-protein signaling of Rs1 by Wei Chun Chang (43479)

Expression of selected genes measured by microarray and qPCR in membrane cultured IPEC-J2 cells regulated in all DON treatments. by Anne-Kathrin Diesing (326868)

“…<p>Regulation of transcripts of (<b>A</b>) TRA1 and (<b>B</b>) CAV2 in response to apical and basolateral DON (200 and 2000 ng/mL) treatment. mRNA levels are given as fold increase or decrease over untreated control. …”

rhIL-17A stimulated alveolar macrophages show increased killing of opsonised pneumococci. by Adam K. A. Wright (173046)

“…<p>Human alveolar macrophages from non-colonised volunteers were exposed to opsonised D39 pneumococci in the presence of rhIL-17A or a vehicle control (v/v). Percentage changes in CFU following rhIL-17A (<i>y</i>-axis) treatment are shown as increase or decrease relative to vehicle, which was set at 0% for comparison (<i>x</i>-axis). * = <i>p</i><0.05, ** = <i>p</i><0.01 vs 12.5 ng/ml of rhIL-17A.…”

LMWHA inhibits IL-4 or IL-13-induced fibrocyte differentiation. by Anu S. Maharjan (342245)

“…Also, the combination of 300 µg/ml LMWHA and 1 ng/ml IL-4 significantly decreases the number of fibrocytes when compared to 1 ng/ml IL-4 with p<0.05. …”

Feijoa F3 activates autophagy and inhibits NF-κB activity in HCT15 cells. by Noha Ahmed Nasef (760610)

“…A percentage of greater than 100 shows increased inflammatory response in the presence of the ligand when compared to media (no treatment); and a percentage of less than one suggests a decrease in the inflammatory response in the presence of the ligand when compared to media (no treatment) meaning that a condition has inhibited NF-κB signaling. …”

Uniform downscaling of postsynaptic AMPA receptors across the dendritic tree in primary hippocampal cultures. by Mathieu Letellier (6803699)

“…(B) Representative EPSC trace evoked by a pair of brief depolarizations (+100 mV, 50-ms interval) of the presynaptic neuron. …”

<i>klf4</i> is required for the maintenance of the <i>egc</i>^<i>+</i><i>/meg-1</i>^<i>+</i><i>/zfp-1-1</i>^<i>+</i> TRL. by Lu Zhao (296389)

“…(F) FISH depicting a modest decrease in <i>tsp-2</i>⁺ cell number following <i>klf4</i> RNAi. …”

Effect of hypotonic stress and elevated K⁺ on the ECS diffusion parameters in α-syn +/+ and α-syn −/− mice <i>in vitro</i>. by Lesia Dmytrenko (431060)

“…The mean values of the maximum change during application correspond to the time-point of the maximum decrease of α (i.e., the 25^th min in H-50 and H-100 and the 30^th min in 10 mM K⁺); the values for washout correspond to the data point at the 90^th min. …”

Image5_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image1_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image2_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image4_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image6_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image3_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer by Xiaoxiao Sun (20589448)

“…Doxycycline (Dox, 100 ng/mL) was administered concurrently with targeted drugs to ensure PRMT1 knockdown. …”

Treatment Satisfaction and Well-Being in Patients with Myopic Choroidal Neovascularization Treated with Ranibizumab in the REPAIR Study by Winfried M. Amoaku (748780)

“…Treatment satisfaction significantly increased over the study period (<i>p</i> = 0.0001). Mean MacTSQ scores increased by 9.7 and 10.0 in patients treated in their WSE and BSE, respectively. …”

BV and GSK3β siRNA modulate the levels of cytokines in the supernatants of cultured splenocytes. by Ran Fu (434520)

“…<p>Both BV (100 μg/mL) and GSK3β siRNA (100 pmol/mL) were shown to significantly decrease the levels of IL-4, but increase the levels of IL-10 and TGF-β1 in the supernatants of cultured splenocytes. …”

Mechanosensitive response in <i>pain</i> loss of function individuals. by Sébastien Sénatore (80383)

“…In the three mutants and in the RNAi line, a significant decrease is observed following <i>painless</i> knock-down. …”