TbCDC34 activity is modulated by compound CC0651. by Federico Rojas (480253)

“…Samples treated with CC0651 showed a decrease of cells with 1N1K and an increase of cells with 2N2K. …”

Effect of IL-17A, IL-17F or IL-22 on TER of cultured ARPE-19 monolayer. by Ying Chen (9697)

“…Incubation of ARPE-19 monolayers with 50 ng/ml IL-17A or IL-17F induced a gradual decrease of TER, and a significant effect occurred 5 days (p = 0.019, p = 0.045) after stimulation. …”

Effects of (a) AG-490 and (b) WHI-P154 on IFN-γ-induced nitric oxide (NO) generation in J774 macrophages by Outi Sareila (66176)

“…</p><p></p> After 24-hour incubation with IFN-γ (5 ng/mL), the supernatants were collected and nitrite was measured in the culture medium as an indicator of NO production by Griess reaction. …”

IL-1β treatment does not induce cell death. by Himakarnika Alluri (2735689)

“…<p>IL-1β (10 ng/mL; 2 hours) treatment had no effect on cell viability (n = 5). …”

(S)-2 induced apoptosis in LNCaP cells. by Anna Laurenzana (296271)

“…Mitochondrial depolarization is indicated by a decrease in the red/green (R/G) fluorescence intensity ratio <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058267#pone.0058267-Salvioli1" target="_blank">[32]</a>. …”

HO-1 deficiency leads to poor bacterial clearance <i>in vivo</i> and <i>in vitro</i>. by Satindra Gahlot (3615662)

“…Data are means ±SD of 3 independent experiments. Statistical significance *p<0.001 a significant decrease compared to MRSA alone exposed cultures; and #p<0.001 a significant increase compared to MRSA +CoPP treated cultures. …”

Supplementary Material for: Nomograms of Fetal Right Ventricular Fractional Area Change by 2D Echocardiography by Guirado L. (6174176)

“…In contrast, RV FAC showed a slight quadratic decrease throughout gestation (mean RV FAC ranged from 36% at 18 weeks of gestation [10–90th centiles: 25–47%, respectively] to 29% at 41 weeks [10–90th centiles: 18–40%, respectively]). …”

The <i>casy-1</i> isoforms functions in GABAergic neurons to regulate synaptic transmission. by Shruti Thapliyal (4951993)

“…Cholinergic synapses are largely normal in <i>casy-1</i> mutants, while GABAergic synapses showed a subtle but significant decrease in fluorescent intensity when compared to WT animals. …”

Syntheses, Crystal Structures, and Physical Properties of La₅Cu₆O₄S₇ and La₅Cu_6.33O₄S₇ by George H. Chan (2419864)

“…In going from La₅Cu₆O₄S₇ to La₅Cu_6.33O₄S₇, the disruption of the ²_∞[Cu₆S₆⁵⁻] layer and the decrease in the overall Cu²⁺ (3d⁹) concentration lead to a significant decrease in the electrical conductivity.…”

Syntheses, Crystal Structures, and Physical Properties of La₅Cu₆O₄S₇ and La₅Cu_6.33O₄S₇ by George H. Chan (2419864)

“…In going from La₅Cu₆O₄S₇ to La₅Cu_6.33O₄S₇, the disruption of the ²_∞[Cu₆S₆⁵⁻] layer and the decrease in the overall Cu²⁺ (3d⁹) concentration lead to a significant decrease in the electrical conductivity.…”

UTX-1 is required for VPA action in <i>C. elegans</i> embryos and in human cells. by Rakel Brendsdal Forthun (121022)

“…Numbers shown are arbitrary units compared to negative control siRNA. The blot shows a 60% decrease in UTX by siRNA treatment, confirming the efficacy of transfection. …”

EGFR inhibitor differentially modulates the expression of antigen presenting molecules and PD-L1 on HaCaT cells. by Jin S. Im (234975)

“…(B) HaCaT cells were treated with IFNγ at different concentrations ranging 1 pg/ml to 1000 pg/ml in the presence or absence of erlotinib at concentration of 10 μM for 24 hours, and assessed for surface expression of MHC-I, MHC-II, and PD-L1 in Mean Fluorescence Intensity (MFI). While the expression of MHC-I and MHC-II on HaCaT cells was further up-regulated in the presence of erlotinib and IFNγ at all dose range tested for MHC-I and at a greater than 1pg/ml for MHC-II compared to IFNγ alone, IFNγ induced overexpression of PD-L1 was abrogated by the addition of erlotinib to IFNγ at a greater than 100 pg/ml. …”

BPLF1 deubiquitinates TOP2 and stabilizes TOP2ccs. by Jinlin Li (2267896)

“…Clearance was calculated as 1- (intensity of the smears after treatment for 4 h/intensity of the smears after treatment for 30 min) x100. Treatment with MG132 reduced the clearance of TOP2ccs in BPLF1 negative cells and a similar reduction was achieved by expression of BPLF1 in Dox treated cells. …”

Blunted excitability of aortic baroreceptor neurons in diabetic rats: involvement of hyperpolarizationactivated channel by Yu-Long Li (311230)

“…Furthermore, HCN channel blockers (5 mM cesium chloride and 100 mM ZD-7288) significantly reduced HCN currents and increased action potential frequency of the AB neurons in sham and T1D rats. …”

Activation of the NF-κB, JAK-STAT and TRAF pathways. by Sven Brandau (70736)

“…Values ≥ 2.0 are set as a significant increase of gene expression and values≤0.5 are set as a significant decrease of gene expression after LPS stimulation. 2^−ddCT = 2^{−(dCT Target – dCT Reference) LPS stimulated – (dCT Target – dCT Reference)}^unstimulated. …”

Data_Sheet_1_Genome-Wide Profiling of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Potato Response to DON Stress.PDF by Yan Shi (166398)

“…In particular, the 20 ng/ml treatment showed the largest decrease in all three contexts of methylation levels, especially CHH contexts in transposon regions. …”

Data_Sheet_2_Genome-Wide Profiling of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Potato Response to DON Stress.xlsx by Yan Shi (166398)

“…In particular, the 20 ng/ml treatment showed the largest decrease in all three contexts of methylation levels, especially CHH contexts in transposon regions. …”

VEGF reduces miR-30b expression in HUVECs. by Grant A. Howe (2558611)

“…(B) Cells were serum starved overnight in MCDB 131 with 0.5% FBS and stimulated with VEGF (50 ng/ml) for 24 hours. …”

Aging-related limit of exercise efficacy on motor decline - Fig 7 by Jennifer C. Arnold (4621795)

“…</b> TH standard was loaded from 0.5 to 4 ng. A non-exercise (NE) and exercise (E) result is shown representing the overall ~25% decrease in TH expression in the exercise group. …”

Knockdown of BMPRII did not affect BMP4 elevated basal [Ca²⁺]_i and SOCE in PASMCs. by Yi Zhang (9093)

“…(B) represting time course of quenching of Fura-2 AM fluorescence at 360 nm by 200 µM Mn²⁺ after perfusion with Ca²⁺ -free KRBS (0 Ca²⁺) containing Nifedipine (5 µM) and CPA (10 µM) in distal PASMCs treated with 50 ng/ml BMP4 (n = 4 experiments in 110 cells) or vehicle for 60 h, normalized to fluorescence at time 0 (F/F₀). …”