Knockouts of <i>gpr-3</i> lack cAMP signaling response to melatonin. by Cathryn S. D. Maienza (20629929)

“…<p>Difference in relative cAMP concentration between <i>gpr-3</i>^<i>+</i> (N380-1, n = 6), <i>gpr-3</i>^{<i>-</i> (}N380-2, n = 6), and <i>gna-1</i>^<i>-</i>(n = 6) strains after 10-minute treatment with 5ng/mL melatonin in sterile water. Untreated group was treated only with water. …”

Celastrol has an inhibitory effect on TNFα-induced NF-κB signaling in MDA-MB-231 cells. by Laura Mezzanotte (223692)

“…<p>(3.A) Graph representing the decrease in fold NF-κB induction in MDA-MB-231 cells using celastrol by the multicolor assay (* p value <0.05; ** p value <0.01). (3.B) Composite image of the unmixed spectrum of luciferases: green signals represent CBG99 emission, red signals represent PpyRE9 emission spectrum and blue signals represent ExtGluc expression in control cells (first column) and cells treated with TNFα in combination with increasing concentrations of celastrol (0.1–3 µM). (3.C) Left: graph reporting the relative band intensity of p65 protein from the nuclear extract of control sample and samples treated with TNFα (10 ng/ml) or TNFα + celastrol (0.1 µM; 0.5 µM and 1 µM). …”

Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition - Fig 9 by Himakarnika Alluri (2735689)

“…Animals were divided into sham (n = 6), vehicle + sham (n = 6), vehicle + TBI (n = 5) and melatonin + TBI (n = 6). Data are expressed as ng/brain cortex ± SEM. ‘*’ indicates statistical significance. …”

TGF-β₁ dependent effects on AP activity by SB431542 are depending on time. by Sabrina Ehnert (359631)

“…<p>Primary human osteoblasts stimulated with 5 ng/ml hra TGF-β₁ in the presence or absence of 20 nM SB431542. …”

Phenotypes of ovary cultures treated with FST288. by Zhengpin Wang (147664)

“…<p>Ovaries at 17.5 dpc were cultured for 7 days without treatment (as a control) or with 500 ng/mL FST288. …”

Serum brain-derived neurotrophic factor reflects the lower inflammation, lipid level, and major adverse cardiac and cerebrovascular events risk in maintenance hemodialysis patients by Hui Du (639270)

“…Our study shows that BDNF was notably (more than two folds) decreased in MHD patients compared with that in HCs (median (interquartile range) value: 5.5 (3.1–9.4) vs. 13.2 (9.4–19.1) ng/mL). …”

Data Sheet 1_Thermodynamic integration in combined fuel and power plants producing low carbon hydrogen and power with CCUS.docx by Daniel Mullen (5681870)

“…A first of a kind techno economic analysis concludes that the improvements present in a CO₂ abated CFP plant results in a 15.1%–17.3% and 7.6%–8.0% decrease in capital and operational expenditure respectively for the CO₂ capture cases. …”

Temporal trends in Human T-Lymphotropic virus 1 (HTLV-1) associated myelopathy/tropical spastic paraparesis (HAM/TSP) incidence in Martinique over 25 years (1986-2010) by Stephane Olindo (4976189)

“…Between 1996–2000 and 2011–2015 study periods, the HTLV-1 seroprevalence significantly decreased by 63%.</p><p>Conclusion</p><p>Martinique faces a sudden and rapid decline of HAM/TSP incidence from 2001 in comparison to 1986–2000 periods. …”

Peptide membrane interaction. by Mônica S. Freitas (357825)

“…<p>(A) Living Vero cells were incubated with wtEBO₁₆ at 25 (circles) or 37°C (square). …”

Supplementary Material for: Diagnostic value of sST2, VCAM-1 and adiponectin in patients with breast cancer to predict anti-tumor treatment-related cardiac events: A pilot study by Rosenkaimer S.L. (12968150)

Expression of specific MSN markers. by E. M. André (4911670)

“…(D) Striatal GAD67 -positive neuron number also decreased progressively with a 30% decrease at day 4, 45% at day 7 and 100% at day 30, compared to day 0 representing 100%. …”

The Impact of Varying the Target Population for HPV 16 Vaccination by Ruanne V Barnabas (16126)

“…Vaccination at age 20 y produced a 63% decrease and at age 25 y, a 41% decrease, in cancer incidence.…”

data_share by Qi Zhu (9428795)

“…In the present study, by calculating the electron bounce-averaged pitch angle diffusion coefficients with kappa plasma dispersion relations, we investigate the sensitivity of hiss-induced cyclotron-resonant electron scattering loss to the spectral index <i>κ</i> under a variety of superthermal plasma conditions. Our results demonstrate that, with increasing <i>κ</i>, the diffusion coefficients of ∼20 - 100 keV radiation belt electrons significantly decrease at lower pitch angles and increase at higher pitch angles. …”

HMGB1 induces Src activation. by Mengchen Zou (725646)

“…Representative immunoblots showing that PP2 (C) and CGP77675 (D) decreased HMGB1-induced Src phosphorylation. Cells were preincubated with 1, 2.5, 5, or 10μM PP2 or 0.5, 1, 2.5 or 10 μM CGP77675 for 1 h, respectively. 200 ng/ml HMGB1 was then added and cells were incubated for an additional 24h. …”

Data Sheet 1_Dietary intake in healthy older individuals is associated with lipopolysaccharide binding protein a biomarker of gut function: an exploratory cross-sectional study.doc... by Debra Jones (18813)

“…When further adjusted for C-reactive protein (CRP), a marker of inflammation, LBP decreased by an additional 6.9 ng/mL for fibre, increased by an additional 4.0 ng/mL for fat and decreased by an additional 3.7 ng/mL for carbohydrate. …”

Morphologic and epithelial mesenchymal transition (EMT) marker changes in human lung cancer cells with opioids, growth factors and signal transduction pathway inhibitors. by Frances E. Lennon (541593)

“…<p><b>Panel A</b>: H358 human NSCLC cells were either untreated (control), treated with 100 nm morphine or 100 ng/ml insulin growth factor (IGF) for 96 hours and brightfield images were obtained (20×). …”

Data_Sheet_1_Effect of early administration of dexamethasone in patients with COVID-19 pneumonia without acute hypoxemic respiratory failure and risk of development of acute respir... by Anabel Franco-Moreno (19164412)

“…The risk of ARDS was determined based on specific criteria: elevated lactate dehydrogenase levels over 245 U/L, C-reactive protein levels exceeding 100 mg/L, and a lymphocyte count below 0.80 × 10⁹/L. …”

Fig 1 - by Can Yang (337581)

“…As shown in Fig 1, the upper bound exhibits a clear decreasing trend with the n and k increase.…”

Effect of HSL on cell viability. by Ashwath S. Kumar (625580)

“…At 48 h, cell viability decrease was significant at O-DDHSL concentration at or above 100 µM (P≤0.02; n = 3). …”

The Expression of NFκB and Downstream Angiogenic Proteins in rho/VEGF Mouse Model. by Michael DeNiro (297385)

“…YC-1-treated retinas exhibited a significant decrease in the protein expression levels as compared with DMSO-treated retinas. …”